scholarly journals Ischemic stroke: Observations and analysis of stroke patients admitted in a tertiary hospital of Kathmandu

2019 ◽  
Vol 8 (2) ◽  
pp. 66-71
Author(s):  
Dipesh Shakya ◽  
Rabindra Shrestha ◽  
Krishna Dhungana ◽  
Raisha Kafle ◽  
Sabnam Bhatta
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Carotid Artery ◽  
Public Awareness ◽  
Tertiary Care ◽  
Care Hospital ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Carotid Artery Atherosclerosis ◽  
Common Risk Factors

Background: Stroke is a disabling condition that has physical and mental impact on a patient’s life. Stroke is an important morbidity for low and middle income countries like Nepal. Hypertension, diabetes, smoking, and dyslipidemia are common risk factors in this regard and are inadequately controlled; mainly because of poor public awareness, inadequate infrastructure, lack of service and qualified manpower.Objectives: This study aims to provide insight into the epidemiology and risk factors in ischemic stroke patients.Methodology: A descriptive cross sectional study was conducted in 92 ischemic stroke patients at a tertiary care hospital Kathmandu Medical College and Teaching Hospital (KMCTH), Sinamangal, Nepal from December 2017 to June 2018. Consecutive sampling technique was used and data was collected from ischemic stroke patients above 14 years of age who were admitted in the Department of Neurology. Information regarding pre-morbid and morbid conditions, imaging findings as well as results was obtained from biochemical analysis of blood after taking consent from the patient or patient’s relative. Statistical Package for the Social Sciences Version 20 was used as a tool for statistical analysis.Results: Their mean age was 63.25 years with standard deviation of 16.45. Dyslipidemia was the most commonly found risk factor which was present in 77.2% of the subjects, followed by smoking (59.8%), presence of carotid artery atherosclerosis (59.8%), hypertension (50%), atrial fibrillation (26.1%) and diabetes mellitus(15.2%). Smoking was significant in males and heart disease was mostly seen in females.Conclusion: Dyslipidemia and smoking were the most common risk factors followed by carotid artery atherosclerosis. Patients with hypertension and dyslipidemia had higher incidence of stroke in both young and elderly group.

scholarly journals Study On Stroke In Young Patient Due To Cardiac Disease in Tertiary Care Hospital in Dhaka City

2016 ◽  
Vol 17 (2) ◽  
pp. 95-99
Author(s):  
Sanjoy Kumar Saha ◽  
Prodip Kumar Biswas ◽  
Meherunessa Mukta ◽  
Mohammed Shahadat Hossain ◽  
Mimal Kumar Basu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Ischemic Stroke ◽  
Cardiac Disease ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Care Hospital ◽  
Stroke Patients ◽  
Female Ratio ◽  
Valvular Heart Diseases

Objectives: Study of the risk factors associated with stoke due to cardiac disease in age group between 18 to 45 years of age,evaluate the risk factor of hospitalized stroke patients & to search for cardiac disease associated with stroke also appropriate preventive measure applicable for our country.Materials & Methods: Non randomized prospective observational study was carried out in the department of Neurology, Medicine & Cardiology unit of Dhaka Medical College Hospital between the periods of July 2009 to December 2009. Fifty (50) consecutive indoor patients more than 18 years of both sex admitted with suspicion of stroke. Diagnosis of stroke will be made from details clinical history clinical examination and confirmed by CT scan or MRI.Result: Fifty patients were randomly chosen for this study, of which 26 (52%) patients were male, 24 (48%) patients were female & male: female ratio was 1.08:1. Highest incidence of stroke was in between 3rd & 4th decade. The incidence of ischemic stroke 46 (92%) & hemorrhagic stroke 4(8%).Cardio embolism is the major (92%) risk factor for ischemic stroke. Among the cardiac risk factors, valvular disease (64%), MI (16%), &IHD (10%), Atrial fibrillation 8%, Patent foramen ovale 2%.Among the patients 33.33% of women with cerebral infarction were using OCP. Majority of the patients in this study were sedentary worker (45%). Among the stroke patients 8% & 10% had previous H/O stroke & TIA respectively.Conclusion: In this study a number of modifiable risk factors were identified, of which valvular heart disease & HTN are important risk factor next are DM & IHD smoking. Most of the valvular heart diseases are rheumatic in origin, which can be prevented through primary & secondary prevention of rheumatic fever.J MEDICINE July 2016; 17 (2) : 95-99

scholarly journals Incidence and Risk Factors of Acute Kidney Injury in Acute Stroke - in a Tertiary Care Hospital

2019 ◽  
Vol 8 (1) ◽  
pp. 12-18
Author(s):  
Nitai Chandra Ray ◽  
Md Ayub Ali Chowdhury ◽  
Md Abdul Muqeet ◽  
Mahmud Javed Hasan ◽  
Ashutosh Saha Roy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Acute Stroke ◽  
Tertiary Care ◽  
Kidney Injury ◽  
Care Hospital ◽  
Stroke Patients ◽  
College Hospital ◽  
Cross Sectional

Acute kidney injury (AKI) is a common complication after acute stroke. Multiple additional risk factors are also responsible for development of AKI during acute stroke. This cross sectional observational study was conducted with a total of 240 newly detected computed tomography (CT) confirmed acute stroke patients in Mymensingh Medical College Hospital with an aim to find out the incidence and risk factors of AKI in acute stroke. In this study, AKI developed in 15.42% of all types of acute stroke and more commonly in haemorrhagic stroke than in ischaemic stroke (23.44% vs. 12.50%, P<0.05). AKI was found more frequently (54.05%) in old >60 years age group and in male patients(17.93% vs. 11.58% & P>0.05). Again, AKI developed most commonly in chronic kidney disease (CKD) (33.33%, P<0.05) and then in diabetes mellitus (DM) (31.03%, P<0.05), in ischaemic heart disease (IHD) (28.11%, P<0.05), in hypertension (21.14%, P<0.05), in previous stroke (15.22%, P>0.05), in dyslipidaemia (13.33%, P>0.05), and in smoker (9.89%, P>0.05). Family history of (H/O) DM was present in 30.00% (P>0.05) and that of hypertension and kidney disease was present in 24.44% (P>0.05) and 25.00% (P>0.05) of stroke patients, respectively. Among the AKI patients, majority (70.27%) had hypertension and 37.84% had CKD, 29.73% had IHD. DM and smoker were 24.32%of each. Family H/O of hypertension, DM and kidney disease was present in 29.73%, 16.22% & 13.51 % of AKI patients, respectively. So, this study had identified several important risk factors of AKI, in particular age, sex, smoking, hypertension, DM, IHD, CKD and types of stroke. So, the risk score could be easily calculated to predict the risk of AKI in stroke patients. And thus to prevent the development of AKI is of utmost importance to reduce the related morbidity and mortality of acute stroke patients. A multicenter nationwide intensive research is needed to identify the precise mechanism, risk factors, their relation and actual outcome of AKI that develop in patients with acute stroke. CBMJ 2019 January: vol. 08 no. 01 P: 12-18

scholarly journals Clinical Profile of Stroke Patients Attended in a Tertiary Care Hospital- Study of 219 cases

2016 ◽  
Vol 32 (1) ◽  
pp. 16-20
Author(s):  
Nayeem Anwar ◽  
Md Rezaul Karim Khan ◽  
Nawreen Binte Anwar ◽  
Shamsun Nahar ◽  
- Md Shahidullah
Keyword(s):  
Risk Factors ◽  
Recurrent Stroke ◽  
Tertiary Care ◽  
The Body ◽  
Clinical Profile ◽  
Care Hospital ◽  
Age Group ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Study Results

Background: Stroke is serious pathology with a immense impact on the functional and vital prognosis. It is the leading cause of death worldwide. The objective of the study was to observe clinical profile of stroke patients and important risk factors. Methods: It was a cross-sectional descriptive study conducted in the department of Neurology, BangabandhuSheikh Mujib Medical Universiy(BSMMU), Shahbag, Dhaka from August 2014 to November2015. All patients above 18 years of age and both sexes attending the above mentioned department meeting all inclusion and exclusion criterias and confirmed CT/MRI scan of Brain were included in this study. Results: A total of 219 patients were studied. Maximum 93(42.5%) patients were in age group of 61-70 years followed by 51(23.3%) and 30(13.7%), in the age group of 51-60 years and 71-80 years respectively. Male 138(63%) were predominant than female 81(63%). 78(35.61%) patients had weakness in both sides of the body, 66(30.1%) had weakness in the left side and 36(16.4%) had weakness in the right side of the body. 190 (87.7) patients had ischemic stroke and 29(12.3%) had hemorrhagic stroke. Among risk factors dyslipidemia was in 185(84.5%) patients, hypertension, smoking habits, diabetes mellitus and ischemic heart disease were present in 165(75.3%), 120(54.8%), 105(47.9%) and 42 (19.2%) patients respectively. H/O recurrent stroke was present in 55(25%) cases. Conclusion: Stroke cases were male predominant where dyslipidaemia was the most common risk factor, most common type of stroke was ischemic, most common presentation was hemiplegia/monoplegia and commonest age of presentation was seventh decade. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 16-20

scholarly journals Hyperhomocysteinaemia among Acute Ischaemic Stroke Patients in a Tertiary Care Centre in Thiruvananthapuram, Kerala – A Cross-Sectional Study

2021 ◽  
Vol 8 (19) ◽  
pp. 1326-1331
Author(s):  
Deepa Gopalakrishna ◽  
Rupa Gopinathan ◽  
Saboora Beegum ◽  
Thomas Iype
Keyword(s):  
Risk Factors ◽  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Homocysteine Level ◽  
Statistical Tests ◽  
Tertiary Care ◽  
Care Hospital ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Total Homocysteine

BACKGROUND Over the last three decades, prevalence of stroke has been high in India, while the Western countries have witnessed a downward slide. Epidemiological studies suggest that hyperhomocysteinaemia might be a potentially modifiable nonlipid risk factor associated with stroke, in addition to the long-recognized factors like hypertension, diabetes mellitus, hyperlipidaemia and smoking. Hyperhomocysteinaemia occurs due to deviation in the metabolic pathway of methionine, attributed by deficiency of vitamins, enzymes and other factors. The present study was undertaken to assess the proportion of hyperhomocysteinaemia in patients with acute ischemic stroke. We also compared the risk factors associated with stroke and serum levels of homocysteine. METHODS This is a cross sectional observational study conducted in a tertiary care hospital. The sample size was 140. Both male and female consecutive patients of age more than 18 years, with first attack of acute ischaemic stroke admitted in the Department of Neurology were selected. Baseline fasting serum samples were obtained for testing serum homocysteine levels. Statistical tests used were proportion, chi square and logistic regression. RESULTS Among 140 acute ischaemic stroke patients, total homocysteine level was raised in 83.6 % cases. The prevalence of moderate hyperhomocysteinaemia in our study was 65.4 % and intermediate hyperhomocysteinaemia was 17.9 % among stroke patients. The mean (± SD) homocysteine level was 22.75 (± 8.19). CONCLUSIONS A strong association was found between hyperhomocysteinaemia and acute ischaemic stroke. We could not find any significant correlation between total homocysteine level and most risk factors of stroke. KEYWORDS Stroke, Homocysteine, Risk Factors, Endothelial Dysfunction, Atherosclerosis, B Vitamins

scholarly journals High Waist to Hip Ratio as a Risk Factor for Ischemic Stroke Patients Admitted in a Tertiary Care Hospital

1970 ◽  
Vol 9 (1) ◽  
pp. 30-34
Author(s):  
Md Habib Khan ◽  
Sanjoy Kumar Chakraborty ◽  
Rajat Sanker Roy Biswas
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Stroke Patient ◽  
Tertiary Care ◽  
Care Hospital ◽  
Ischemic Stroke Patient ◽  
College Hospital ◽  
Cross Sectional ◽  
Waist To Hip Ratio ◽  
Co Morbidity

Context: Stroke is a problem now days. The purpose of this study is to see the association of high waist-to-hip ratio with ischemic stroke and also to see the correlation with other risk factors of ischemic stroke. Study type: Hospital based cross sectional descriptive study Methods: It is a study conducted on purposively selected (non probability) hospitalized patients who had been admitted into neuromedicine ward of Chittagong Medical College Hospital (CMCH), Chittagong prooved during a period of 6 months extending from 1st January 2009 to 31st June 2009. 50 cases with CT scan prooved ischemic stroke of brain were interviewed and examined and had measurements of waist and hip circumference and waist to hip ratio (WHR) were calculated. Results: 64% of the ischemic stroke patient had abnormal WHR. The correlation with other risk factors showed that 90% of ischemic stroke patient had other co-morbidity. Among them 76% patient had hypertension, 38% patients had history of smoking, 16% patients had diabetes mellitus and 12% patients had dyslipidaemia. Conclusion: The results reveal that high waist to hip ratio might have an association with ischemic stroke. Key words: Ischemic stroke; Waist-to-Hip Ratio (WHR). DOI: http://dx.doi.org/ 10.3329/bja.v9i1.8145 Bangladesh Journal of Anatomy January 2011, Vol. 9 No. 1 pp 30-34

scholarly journals Seroprevalence ofChlamydia PneumoniaeAntibodies in Stroke in Young

2009 ◽  
Vol 36 (6) ◽  
pp. 725-730 ◽  
Author(s):  
V. C. S. Srinivasarao Bandaru ◽  
D. Babu Boddu ◽  
V. Laxmi ◽  
M. Neeraja ◽  
S. Kaul
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Magnetic Resonance ◽  
Acute Ischemic Stroke ◽  
Tertiary Care ◽  
Control Group ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Stroke Patients ◽  
Stroke In Young

Background:Younger patients, aged below 45 years, usually lack the conventional risk factors of stroke whereas infections, especially in developing countries, may play a role. There have been many reports in the last decade about the association ofChlamydia pneumoniae(C.pneumoniae) and atherosclerosis involving cerebral vessels.Objective:To investigate the seroprevalence ofC.pneumoniaeIgG and IgA antibodies in patients aged below 45 years with acute ischemic stroke.Methods:This study was done at a tertiary care hospital in South India between January 2004 and December 2006 where we recruited consecutive patients aged less than 45years with acute ischemic stroke. Age and sex matched controls were recruited from the outpatient department with non stroke diagnosis. All stroke patients underwent CT (Computerized Tomography), MRI (Magnetic Resonance Image), MRA (Magnetic Resonance Angiography), Transthoracic Echocardiography and Carotid Doppler for stroke sub group diagnosis. We measuredC.pneumoniaeantibodies IgG and IgA by microimmunofluorescence technique in all patients and controls.Results:A total of 120 patients and 120 controls were studied over a period of two years. We foundC.pneumoniaeantibodies in 29.1% (35/120) stroke patients and in 12.5% (15/120) control subjects (p=0.002).C.pneumoniaeIgG antibodies were found in 27.5 % (33/120) of stroke patients and 12.5% (15/120) of controls (p=0.006). IgAantibodies were observed in 5 % (6/120) of strokes and none in control group (p=0.03). After adjustment of all risk factorsC.pneumoniaeIgG seropositivity showed odds ratio of 2.6; 95% Confidence Interval 1.2-5.6.Conclusions:C.pneumoniaeIgG antibodies were found to be associated with ischemic stroke in young.

scholarly journals An observational study from a new tertiary care hospital in North Odisha: clinical and etiological profile of acute ischemic stroke patients

2019 ◽  
Vol 6 (5) ◽  
pp. 1605
Author(s):  
Bibhu P. Behera ◽  
Partha S. Mohanty
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Observational Study ◽  
Acute Ischemic Stroke ◽  
Hemorrhagic Stroke ◽  
Tertiary Care ◽  
Care Hospital ◽  
Stroke Patients ◽  
Middle Income ◽  
Stroke Subtypes

Background: Worldwide, cerebrovascular accidents (stroke) are the second leading cause of death and the third leading cause of disability. According to WHO estimation, by 2050 nearly 80% of stroke cases may occur in low and middle-income countries like China and India. It is critical that we understand the etiology causing the stroke so that appropriate treatment can be initiated in a timely fashion. Furthermore, understanding the risk factors associated with stroke is important before primary and secondary preventive measures can be prescribed to the patient.Methods: This observational study was carried out amongst 481 acute ischemic stroke patients that fulfils the inclusion and exclusion criteria and admitted in medicine ward of Pandit Raghunath Murmu Medical College and Hospital, Baripada, Dist. Mayurbhanj, Odisha, India from June 2018 to January 2019. Results: In our study, 481(60.43%) patients had ischemic stroke and 315 (39.57%) patients had hemorrhagic stroke. The incidence of stroke is maximum in 51-70 years of age group which comprises of 59.46% of total patients. The average age + SD were 61.4±13.1 in our study. The most common risk factor was hypertension with 69.85% followed by dyslipidemia 51.77%. Most common clinical presentation was hemiplegia (72.35%) followed by speech involvement (59.46%). Most common site of infarct was parietal (22.25%), followed by periventricular (12.68%).Conclusions: Most of the patients had ischemic stroke as compared to hemorrhagic stroke. It was more common in males. The study contributes to understanding of demographic characteristics, risk factors, and stroke subtypes in acute ischemic stroke. The importance of various risk factors among ischemic stroke subtypes should be stressed for prompt preventive strategies and treatment.

scholarly journals Impact of hyponatremia on outcome of acute ischemic stroke in a tertiary care hospital.

2019 ◽  
Vol 26 (10) ◽  
pp. 1789-1793
Author(s):  
Aneela Altaf Kidwai ◽  
Jamal Ara ◽  
Shumaila Abdul Rasheed ◽  
Najeebullah ◽  
Saleemullah Paracha
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Sodium ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Stroke Patients ◽  
Cerebral Salt Wasting ◽  
Cross Sectional ◽  
Salt Wasting

Objectives: To determine the frequency and impact of hyponatermia on outcome in patients of acute ischemic stroke admitted to a Tertiary Care Hospital, Karachi. Study Design: Prospective, cross-sectional, observational study. Setting: Department of Medicine, Abbasi Shaheed Hospital, Karachi. Period: January 2015 to May 2018. Material and Methods: A total of 110 patients of both gender presented with acute ischemic stroke and hyponatermia (2 consecutive serum sodium levels (< 135 mEq/L). Diagnosis of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) and cerebral salt wasting (CSW) was based on predefined criteria. Mortality was considered in terms of modified Rankin Scale with score of 6 within four weeks of admission. Data was analyzed by using SPSS Version 20. Result: Out of 110 acute ischemic stroke patients, 66 (60%) were male and 44 (40%) were female. The mean age was 61.45 ± 11.8 years. Mean serum sodium level was 128.4 ± 6.07. Older ages are associated with high mortality rate of 20%. Moderate (29%) and severe (11%) hyponatremia was associated with 21% and 33% mortality respectively. Overall mortality in patients with hyponatremia was 14.5%. Conclusion: Mortality rates are higher in acute ischemic stroke patients presented with moderate to severe hyponatremia.

scholarly journals Pattern of Stroke in Diabetic and Non-Diabetic Patients Admitted at a Tertiary Care Hospital, a Cross Sectional Study

2021 ◽  
Vol 2 (5) ◽  
pp. 01-05
Author(s):  
Mubashir Ahmed ◽  
Sohail Ahmed Siddiqui ◽  
Abdul Haq ◽  
Atif Ahmed ◽  
Pir Abdul Hayee ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Stroke ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Haemorrhagic Stroke ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Stroke Patients ◽  
Cross Sectional

Objective: To determine the frequency of diabetic among stroke patients and to compare the pattern of stroke in diabetic and non-diabetic stroke patients admitted at a tertiary care hospital in Hyderabad, Sindh. Methods: A cross sectional study enrolled 148 consecutive adult acute stroke patients admitted at Liaquat University Hospital, Hyderabad, during Sep 2014 to Feb 2015. Demographic, clinical, radio-imaging and laboratory data were collected on structured questionnaire to identify diabetes, type of stroke and different risk factors of stroke. Data was entered and analysed by using SPSS version 16. Association was seen by using Pearson’s Chi-square test and Independent t test. A P value of < 0.05 was considered statistically significant. Results: A total of 148 acute stroke cases were enrolled in the study. Males were 92 (62%). Mean age of study participants was 51.21 ± 10.19 years. Diabetes was found in 104 (70.3%) stroke patients. Ischemic stroke was seen in 101 (68.2%) and haemorrhagic stroke seen in 47 (31.8) stroke patients. Diabetes was more common in ischemic stroke 81 (80.2) as compared to haemorrhagic stroke 23 (48.9%) (P< 0.05). Hospital mortality of stroke patients was 37 (25%). No difference of mortality in diabetic and non-diabetic (P>0.05) stroke patients was recorded. Conclusion: Diabetes was found in majority of stroke patients. Ischemic stroke was more common than haemorrhagic stroke. Ischaemic stroke is more prevalent in diabetic whereas haemorrhagic stroke was more in non-diabetic stroke patients. Prognosis of stroke was bad in both diabetic and non-diabetic stroke patients.

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