Prevalence of Principal Rh Blood Group Antigens in Blood Donors at the Blood Bank of a Tertiary Care Hospital in Southern India

Abstract Objective:To ascertain the frequency of markers of transfusion-transmitted infections. among blood donors in a blood bank at a tertiary care hospital Material and Methods:The study was a retrospective cross-sectional descriptive study, covering from 1stJanuary 2013- October 2018 and was conducted in the blood bank section, in the Department of Pathology at Dow University of HealthSciences, Hospital. All blood donors were screened for hepatitis B, hepatitis C, HIV (I & II), syphilis through electrochemiluminescence and malaria (immunochromatography).Data was entered and subsequently analyzed by statistical package for social sciences (SPSS) version 21. The frequency of infectious disease markers (HbsAg, Anti HCV, HIV, syphilis, and malaria) was calculated among blood donors. Results:The total number of donors in our study was 29732, out of which 2587 donors were positive for an infectious disease.Out of the total donors, 29712 were male and 20 were female. There were 12 volunteer donors and 29720 exchange donors. The mean prevalence of donors with positive infectious markers was as follows; Anti HCV was 3 %, HbsAg was 2.9%, Syphilis was 2.0%, HIV was 0.5% and Malaria was 0.02 %. Conclusion:HbsAg and Anti HCV were the most frequent infections (3%) found in our blood donors, followed by syphilis with a frequency of 2%. Keywords: Blood transfusion, transfusion-transmitted infections, blood donors.

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Distribution of Hepatitis B Virus Genotypes in Blood Donors and Chronically Infected Patients in a Tertiary Care Hospital in Southern India

Clinical Infectious Diseases ◽

10.1086/383144 ◽

2004 ◽

Vol 38 (9) ◽

pp. e81-e86 ◽

Cited By ~ 44

Author(s):

P. Vivekanandan ◽

P. Abraham ◽

G. Sridharan ◽

G. Chandy ◽

D. Daniel ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Blood Donors ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Southern India ◽

Care Hospital ◽

B Virus ◽

Virus Genotypes

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SEROPREVALENCE OF HIV, HBV, HCV AND SYPHILIS AMONG BLOOD DONORS IN KIMS BLOOD BANK HUBBALLI, KARNATAKA, A TERTIARY CARE HOSPITAL

International Journal of Microbiology Research ◽

10.9735/0975-5276.10.3.1020-1023 ◽

2018 ◽

Vol 10 (3) ◽

pp. 1020

Author(s):

S. S. GIRIYAN ◽

N. SINDHUSHREE

Keyword(s):

Blood Donors ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Blood Bank ◽

Care Hospital

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Seroprevalence of markers of transfusion transmissible infections among blood donors at a tertiary care hospital blood bank: a 5 year retrospective study

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20193380 ◽

2019 ◽

Vol 7 (8) ◽

pp. 2976

Author(s):

Irm Yasmeen ◽

Supinder Kour ◽

Imran Khurshid ◽

Aasifa Malik

Keyword(s):

Blood Donors ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Blood Bank ◽

Care Hospital ◽

Serum Samples ◽

Tertiary Care Centre ◽

Healthy Donors ◽

Hiv 1 ◽

Apparently Healthy

Background: Transfusion transmitted infections (TTIs) can be caused by various microorganisms present in the blood of apparently healthy donors. The recipient may get infected after being transfused with the unsafe blood. It is mandatory to screen the blood for HIV 1 and 2, HBV, HCV, Syphilis and Malaria. This study was undertaken to investigate the seroprevalance of Transfusion transmitted infections among blood donors at our tertiary care centre and to compare our study with other studies conducted at different hospitals of the country as well as outside.Methods: A retrospective review of blood donor records was made over a period of 5 years with effect from January 2014 to December 2018 at blood bank, department of Blood Transfusion and Immunohaematology, SKIMS, Soura, Srinagar. Both voluntary and replacement blood donors were selected after taking proper history and examination were included in the study. Serum samples were screened for HIV 1 & 2, HBV (HBsAg) and HCV using ELISA with 3rd generation kits.Results: A total of 56325 blood donors were screened. Out of total 55346 (98.2%) were males and 979 (1.73%) were females. Among them 38969 (69.1%) were replacement donors and 17356 (30.8%) were voluntary donors. The seroprevalance of HBV (HBsAg), HCV and HIV 1and 2 was 0.24%, 0.17% and 0.01% respectively and overall seroprevalance of TTIs was 0.43%.Conclusions: Continuous improvement and implementation of newer techniques like NAT and chemilumenescence for testing of blood for TTIs will reduce the risk of acquiring these infections.lance

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