scholarly journals Effects of Lactobacillus acidophilus on Biochemical Indices and Liver Histology in Streptozotocin-induced Diabetic Rats

2019 ◽  
Author(s):  
Yemisi Adesiji ◽  
Samsudeen Owolabi ◽  
Olubunmi Gloria Ayelagbe ◽  
Adekunle Olowe
Keyword(s):  
Lactobacillus Acidophilus ◽  
Diabetic Rats ◽  
Liver Histology ◽  
Biochemical Indices

scholarly journals Effects of methanol leaf extracts of Loranthus micranthus Linn from three host plants on some biochemical indices of diabetic rats

2018 ◽  
Vol 16 (12) ◽  
pp. 2919
Author(s):  
Uwakwe S Onoja ◽  
Innocent E Nweze ◽  
Nwachukwu Ekere ◽  
Philip F Uzor ◽  
Onyinyechi B Giginna
Keyword(s):  
Host Plants ◽  
Diabetic Rats ◽  
Leaf Extracts ◽  
Biochemical Indices

scholarly journals Effect of Munghurt Lactobacillus acidophilus from Green Beans to Blood Glucose Levels in Alloxan-induced Diabetic Rats

2017 ◽  
Vol 11 (2) ◽  
pp. 41-47
Author(s):  
Eka Noneng Nawangsih ◽  
Sayu Putu Yuni Paryati ◽  
Yoga L. Baklaes ◽  
Euis Reni Yuslianti
Keyword(s):  
Blood Glucose ◽  
Lactobacillus Acidophilus ◽  
Diabetic Rats ◽  
Green Beans ◽  
Glucose Levels ◽  
Blood Glucose Levels

scholarly journals Impact of an Acylanilide Herbicide Propanil on Biochemical Indices in Kidney of Diabetic Rats

2019 ◽  
Vol 12 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Chiagoziem Anariochi ◽  
Femi Ayoade ◽  
Oladeji John Arogu
Keyword(s):  
Diabetic Rats ◽  
Biochemical Indices ◽  
Herbicide Propanil

scholarly journals Amlodipine and valsartan improving effect on the survival rate and deleterious pathological changes in streptozotocin-induced diabetic rats treated with metformin

2019 ◽  
Author(s):  
Israel Olapeju Bolanle ◽  
Eric Kelly Inanemo Omogbai ◽  
Enitome Evi Bafor
Keyword(s):  
Survival Rate ◽  
Antihypertensive Drugs ◽  
Diabetic Rats ◽  
Organ Protection ◽  
Amlodipine Group ◽  
Male Wistar Rats ◽  
Diabetic Treatment ◽  
Biochemical Analyses ◽  
Group B ◽  
Biochemical Indices

Diabetes mellitus (DM) and hypertension usually co-exist, and when this happens, the prognosis would be worse than each disease alone. Given this, we evaluated the possible effects of valsartan and amlodipine administration on metformin-treated diabetic rats models induced by streptozotocin. Male Wistar rats (200–350 g) were fasted overnight. Then, we induced DM by administrating a single dose of 40 mg/kg streptozotocin (IP), which was confirmed after 48 h. Animals with blood sugar ≥ 200 mg/dl were considered diabetic and divided into four diabetic groups of untreated diabetic animals (Group B), diabetic animals treated with metformin (Group C), diabetic animals treated with metformin plus amlodipine (Group D), and diabetic rats treated with metformin plus valsartan (Group E). There was also a group A, consisting of normal rats with no drug treatment. After six weeks of treatment, we sacrificed the animals under chloroform anesthesia, and their blood samples were collected for hematological and biochemical analyses. The mortality rate in untreated diabetic rats was 100% before 6 weeks, but anti-diabetic treatment (metformin) significantly (P < 0.05) improved the survival rate and controlled their blood glucose level. The addition of antihypertensive drugs (amlodipine and valsartan) enhanced this curative effect. The various treated groups showed ameliorations in pathologic changes and biochemical indices, as well as, evidence of organ protection, compared with the untreated diabetic group. The study showed that adding an antihypertensive drug (amlodipine or valsartan) to metformin regimen improved outcomes in diabetic rats compared to using metformin alone.

L‐alanine supplementation improves blood glucose level and biochemical indices in alloxan‐induced diabetic rats

2020 ◽  
Author(s):  
Shamsudeen Umar Dandare ◽  
Ifeanyi Jude Ezeonwumelu ◽  
Tijjani Salihu Shinkafi ◽  
Umar Faruk Magaji ◽  
Abdulbaki Alfa‐Ibrahim Adio ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Diabetic Rats ◽  
Biochemical Indices

scholarly journals The effects of the Lactobacillus acidophilus ATCC 4356 on the oxidative stress of reproductive system in diabetic male rats

2019 ◽  
Author(s):  
Seddigheh Sheikh Hosseini ◽  
Ali Gol ◽  
Moje Khaleghi
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Glutathione Peroxidase ◽  
Normal Saline ◽  
Lactobacillus Acidophilus ◽  
Diabetic Rats ◽  
Male Rats ◽  
Significant Difference ◽  
Anti Oxidant ◽  
The Impact

Background: Oxidative stress plays an important role in the development of diabetic complications. Objective: This study evaluated the impact of pre- and post-treatment with Lactobacillus acidophilus ATCC 4356 on the oxidant and anti-oxidant factors of testis and epididymis in streptozotocin-induced diabetic rats. Materials and Methods: Thirty male Wistar rats (10 wk old) weighing 220-230 g. were divided into five groups (n = 6/ each): 1- normal group, 2- normal lactobacillus group, 3- diabetic group, 4- diabetic + lactobacillus before (DLB) group, and 5- diabetic + lactobacillus after (DLA) group. The normal and diabetic groups received daily 1 mL normal saline for 6 wk. Normal lactobacillus group received daily L. acidophilus for 6 wk. Group DLB received daily L. acidophilus for 2 wk before diabetes and for 4 wk after diabetes. Group DLA received daily 1 mL normal saline for 2 wk before diabetes and L. acidophilus for 4 wk after diabetes. The dose of L. acidophilus was 1 × 109 CFU/mL. Results: The administration of L. acidophilus worsened blood glucose level and reduced the levels of Malondialdehyde (p = ≤ 0.0001) and Hydrogen peroxide (p ≤ 0.0001) and, Catalase and Glutathione peroxidase activity increased in the testis. In epididymis, Glutathione peroxidase and Catalase (p = 0.013) activity increased and Hydrogen peroxide concentration reduced, while Malondialdehyde concentration did not show any changes compared to the diabetic rats. Also, there was no significant difference between DLB and DLA groups, in these markers. Conclusion: Data obtained suggests that L. acidophilus has anti-oxidant effects on the testis and sometime in the epididymis in diabetic rats.

scholarly journals Comparative Study of the Effects of Annona muricata and Tapinanthus globiferus Extracts on Biochemical Indices of Diabetic Rats

2019 ◽  
Vol 11 (6) ◽  
pp. 1365-1370 ◽  
Author(s):  
Atanu Atanu FO ◽  
Avwioroko Avwioroko OJ ◽  
Ilesanmi Ilesanmi OB ◽  
Oguche M Oguche M
Keyword(s):  
Comparative Study ◽  
Diabetic Rats ◽  
Annona Muricata ◽  
Biochemical Indices
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