scholarly journals Unidentical Double Trouble- A Rare Case Report

2020 ◽  
Author(s):  
Tanisha Singh ◽  
Gramani Arumugam Vasugi ◽  
Swaminathan Rajendiran ◽  
. Manickavasagam ◽  
. Shanmuganathan
Keyword(s):  
Cell Carcinoma ◽  
Mediastinal Mass ◽  
Squamous Epithelium ◽  
Muscularis Propria ◽  
Transitional Zone ◽  
Anterior Mediastinal Mass ◽  
Collision Tumour ◽  
Rare Case Report ◽  
Chest X Ray ◽  
Hilar Region

Collision tumours are relatively rare entities and are thus, not well recognised. Collision tumour can be defined as two coexisting but histologically different malignancies involving the same organ or adjacent organ with an equivocal intermediate transitional zone between them. Collision tumours of the lung and oesophagus are very rare. Such cases are diagnosed by Computerised Tomogram (CT) Scan or Chest X-Ray for complaint of dysphagia. Definitive diagnosis is made by tissue biopsy. Here, a 66-year-old male is admitted for evaluation of an anterior mediastinal mass. Radiology revealed an anterior mediastinal mass extending in to the left hilar region and upper lobe of right lung anteriorly and in to the lower end of oesophagus posteriorly. Biopsy was performed. Microscopically, transbronchial biopsy revealed a cellular lesion, composed of round-to-oval cells with streaming nucleus, positive for Immunohistochemistry (IHC) markers, CD-56 and Synaptophysin pertaining to a diagnosis of small cell carcinoma. Biopsy of the oesophageal growth shows nest of dysplastic squamous epithelium which infiltrates into underlying muscularis propria showing features of a squamous cell carcinoma. Multiple fragments of squamous epithelium are also seen with necrotic tissue in vicinity and acute inflammatory exudate. Few cells show multinucleation, molding and margination of chromatin, showing the characteristic morphological features of Herpes oesophagitis. The patient was administered platinum-based Chemotherpy.

scholarly journals Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Mauricio A. Palau ◽  
Amanda Winters ◽  
Xiayuan Liang ◽  
Rachelle Nuss ◽  
Susan Niermeyer ◽  
...  
Keyword(s):  
Vitamin K ◽  
Mediastinal Mass ◽  
Anterior Mediastinum ◽  
Medical Attention ◽  
Anterior Mediastinal Mass ◽  
Vitamin K Deficiency ◽  
K Deficiency ◽  
Chest X Ray ◽  
Work Up

We report a case of a 1-month-old infant with spontaneous thymic hemorrhage secondary to severe vitamin K deficiency. He was brought to medical attention due to scrotal bruising and during evaluation was noted to be tachypneic and hypoxemic. Chest X-ray revealed an enlarged cardiothymic silhouette, and a follow-up echocardiogram revealed a mass in the anterior mediastinum. Routine laboratory work-up revealed severe coagulopathy. Further questioning revealed the patient had not received prophylactic vitamin K at birth. The coagulopathy resolved with administration of vitamin K, and a biopsy confirmed the anterior mediastinal mass was due to spontaneous thymic hemorrhage.

scholarly journals MICROFILARIA IN PERICARDIAL EFFUSION COEXISTING WITH SPINDLE CELL THYMOMA-A RARE CASE REPORT

2011 ◽  
Vol 01 (04) ◽  
pp. 40-42
Author(s):  
Harish S Permi ◽  
Samaga B N. ◽  
Subramanyam K. ◽  
Jayaprakash Shetty K. ◽  
Teerthanath S. ◽  
...  
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Mediastinal Mass ◽  
Spindle Cell ◽  
Pericardial Fluid ◽  
Anterior Mediastinal Mass ◽  
Rare Case Report ◽  
Trucut Biopsy ◽  
Cardiac Intensive Care ◽  
Diethyl Carbamazine

AbstractLymphatic filariasis is common in tropical countries and is endemic in South India. Filariasis presenting with pericardial effusion is rare, coexisting with spindle cell thymoma is still very rare. We report a case of a 53-year-old male who was admitted to cardiac intensive care unit with severe breathless since two days. Cardiac Echocardiogram showed massive pericardial effusion with cardiac tamponade and large anterior mediastinal mass. Pericardial fluid aspiration drained 1.5 litres of hemorrhagic fluid. Cytology examination revealed microfilaria of Wutchereria bancrofti. FNAC and trucut biopsy from anterior mediastinal mass showed features of spindle cell thymoma. He was treated with diethyl carbamazine thrice daily for one month. He refused for excision of thymoma. This case report is a rare coexistence of microfilaria in pericardial effusion with spindle cell thymoma. We stress the need to consider filariasis as differential diagnosis in the evaluation of hemorrhagic pericardial effusion especially in endemic areas.

scholarly journals Metastatic basaloid squamous cell carcinoma of thymic origin

2019 ◽  
Vol 12 (9) ◽  
pp. e228860
Author(s):  
Samuel Phen ◽  
Mindy X Wang ◽  
Matthew Kelling ◽  
Gurjaspreet K Bhattal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Mediastinal Mass ◽  
Abdominal Distension ◽  
Anterior Mediastinal Mass ◽  
Basaloid Squamous Cell Carcinoma ◽  
Comfort Care ◽  
Liver And Kidney ◽  
Basaloid Squamous

A 57-year-old man with a known anterior mediastinal mass presented with abdominal distension, jaundice, and signs of urinary and bowel obstruction. Labs revealed leukocytosis, transaminitis, direct hyperbilirubinaemia and elevated levels of alkaline phosphatase, lactate dehydrogenase and uric acid. Subsequent imaging revealed the anterior mediastinal mass and diffuse liver lesions consistent with metastatic disease. MRI of the spine and brain were negative for metastases. Liver biopsy and immunohistochemistry revealed basaloid squamous cell carcinoma of thymic origin. Treatment with capecitabine was initiated but was complicated by worsening liver and kidney failure. Eventually, due to continued worsening of the patient’s condition and minimal treatment response, capecitabine was stopped during cycle 1 and the patient was discharged to inpatient hospice with comfort care. In this case report, we highlight the presenting features, imaging findings and management of a patient with metastatic thymic carcinoma.

scholarly journals A case report on incidental finding of thymoma as anterior mediastinal mass

2019 ◽  
Vol 8 (6) ◽  
pp. 1441
Author(s):  
Nithin K. T. ◽  
Vikas Kumar ◽  
P. Prasanth
Keyword(s):  
Mediastinal Mass ◽  
Incidental Finding ◽  
Primary Treatment ◽  
Anterior Mediastinum ◽  
Anterior Mediastinal Mass ◽  
Unknown Etiology ◽  
Mediastinal Tumors ◽  
Mediastinal Widening ◽  
Chest X Ray ◽  
Heterogeneous Solid

Thymomas are rare tumors in the anterior mediastinum, representing 50% of anterior mediastinal masses and about 20-30% of all mediastinal tumors. They are of unknown etiology; about 50% of patients with thymomas are diagnosed incidentally with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management, the standard primary treatment for these tumors is Thymectomy. We present a case of 55-year female presented with shortness of breath, cough with expectoration and fever for past ten days. Chest x-ray revealed mediastinal widening. CECT chest showed a well-circumscribed heterogeneous solid enhancing mass lesion. FNAC was planned that showed features in favour of thymoma. Biopsy was done that confirmed lymphocyte rich type B thymoma.

scholarly journals Unique Case of Mediastinal Teratoma with Unusual components

2021 ◽  
Author(s):  
Anand Deodhar ◽  
Dinesh Kulkarni
Keyword(s):  
Mediastinal Mass ◽  
Squamous Epithelium ◽  
Mature Teratoma ◽  
Pancreatic Tissue ◽  
Anterior Mediastinal Mass ◽  
Sebaceous Glands ◽  
Unique Case ◽  
Mediastinal Teratoma ◽  
Slow Growing ◽  
Microscopic Findings

Mature teratoma is a benign, slow growing tumour. It usually affect adults in 20-40 years of age. Teratomas with mature pancreatic tissue are extremely rare. There are only a few cases of teratoma containing mature pancreatic tissue that have been reported in literature. Authors report a case of a 25-year-old male having a large solid cystic anterior mediastinal mass, which on excision, histologically revealed large areas of mature pancreatic tissue along with squamous epithelium with sebaceous glands and keratin, pseudostratified columnar ciliated epithelium, mucin secreting glands, cartilage, pigment and other germ cell derived mature elements. This is a unique case with unusual microscopic findings in the form of predominant pancreatic and also brain tissue along with other elements.

Anterior Mediastinal Paraganglioma Mimicking Thymoma

2012 ◽  
Vol 15 (3) ◽  
pp. 170
Author(s):  
Hee Moon Lee ◽  
Dong Seop Jeong ◽  
Pyo Won Park ◽  
Wook Sung Kim ◽  
Kiick Sung ◽  
...  
Keyword(s):  
Mediastinal Mass ◽  
Aortic Wall ◽  
Anterior Wall ◽  
Ascending Aorta ◽  
Anterior Mediastinal Mass ◽  
Arterial Reconstruction ◽  
Ct Evaluation ◽  
One Year ◽  
Mediastinal Paraganglioma

A 54-year-old man was referred to our institution with hemoptysis and hoarseness of 1 year's duration. A computed tomography (CT) scan showed an anterior mediastinal mass (2.5 cm x 1.0 cm), which was diagnosed as thymoma. The tumor was resected under a sternotomy. The tumor had invaded the anterior wall of the ascending aorta. With the patient under cardiopulmonary bypass, the aortic wall invaded by the mass was resected, and arterial reconstruction was performed with patch material. The tumor was revealed to be a tumor of neuronal origin. The patient's postoperative course was uneventful. The patient was discharged on postoperative day 9. One year after the operation, a follow-up chest CT evaluation showed no specific complications or recurrence.

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