scholarly journals A COMPARATIVE STUDY OF KALYANAKA KSHARA PREPARED BY PUTA METHOD AND FURNACE METHOD TO ASSESS ITS PHYSICOCHEMICAL PROPERTIES

2021 ◽  
Vol 12 (1) ◽  
pp. 53-58
Author(s):  
Neethu Indukumar ◽  
G Jai
Keyword(s):  
Physicochemical Characterization ◽  
Dosage Forms ◽  
Basic Form ◽  
Muffle Furnace ◽  
Animal Products ◽  
Minimal Dose ◽  
Strong Action ◽  
Shelf Life Stability ◽  
Day By Day

Ayurveda, the science of life is as old as the Vedic age and now a days Ayurvedic medicines are becoming popular day by day all across the world. The Ayurvedic therapeutics are mainly based on various kinds of dosage forms. Panchavidha kashaya kalpana is the basic form and many formulations are developed over time having long shelf life, stability, strong action etc. Kshara kalpana is the alkaline substance obtained from the ash of plants, minerals and animal products and has been widely used due to its minimal dose and potential action. Kalyanaka Kshara is a widely used formulation mentioned in our classics which is prepared by Antardhooma vidhi. In the present study Kalyanaka Kshara has been prepared using puta method as well as using muffle furnace. Physicochemical characterization of both the samples were done.

scholarly journals DOSAGE FORM DEVELOPMENT AND PRELIMINARY PHYSICOCHEMICAL CHARACTERIZATION OF TRIKANTAKADI KVATHA

2017 ◽  
Vol 10 (16) ◽  
pp. 52
Author(s):  
Swati Sharma ◽  
Dileep Singh Baghel ◽  
Saurabh Singh ◽  
Sachin Kumar Singh
Keyword(s):  
Physicochemical Parameters ◽  
Dosage Form ◽  
Classical Method ◽  
Physicochemical Characterization ◽  
Dosage Forms ◽  
Remarkable Difference ◽  
Standard Value ◽  
Form Development ◽  
Layer Chromatography

  Objective: This is aimed to study the development of different dosage form and physicochemical characterization of Trikantakadi Kvatha (TK).Methods: Stability, shelf life, non-convenient, and large dosages administration are the major concern for Kvatha. To overcome these problems, an effort has been made to modify the formulation without changing its efficacy into various dosage forms such as tablet, syrup, and tincture. Comparative pharmacognostic, physicochemical, and phytochemical parameters of crude herbs and prepared formulations were investigated. TK was prepared by classical method mentioned in literature and converted into TK syrup, TK Ghana vati, and Trikantakadi tincture (TT). Precaution should be taken during the processing of formulations. TT placed at a dark place in airtight container.Results: Physicochemical and phytochemical investigations are not shown any remarkable variations with various prepared dosage forms. The Rf range observed between the 0.08 and 0.80 follows the standard value when compared with the reference of plant drug used for the preparation of dosage form.Conclusion: The prepared dosages forms were not exhibited any remarkable difference according to thin-layer chromatography studies and physicochemical parameters. However, the developed dosage forms are more stable than kvatha.

Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)

2009 ◽  
Vol 81 (5) ◽  
pp. 971-999 ◽  
Author(s):  
Eli Breuer ◽  
Mukund Shankar Chorghade ◽  
János Fischer ◽  
Gershon Golomb
Keyword(s):  
Biological Sciences ◽  
Drug Delivery ◽  
Crucial Role ◽  
Physicochemical Characterization ◽  
Pharmaceutical Preparations ◽  
Dosage Forms ◽  
Unit Operations ◽  
Scientific Disciplines ◽  
Multidisciplinary Nature

This Glossary of Terms in Pharmaceutics is needed by practitioners in the field of pharmaceutics as this field fulfills an important and crucial role, different from the roles of other scientific disciplines involved in the drug-making process. The glossary contains 168 definitions used in pharmaceutics. These are related to various aspects of this discipline such as: (1) physicochemical characterization of pharmaceutical preparations and the active ingredients they contain; (2) unit operations used in the practice of pharmaceutics; (3) terms related to the various dosage forms; (4) terms related to the various modes and routes of drug delivery; (5) terms used in pharmacokinetics and biopharmaceutics in general, and additional miscellaneous terms. The field of pharmaceutics itself is of a multidisciplinary nature as its practitioners come from a variety of disciplines, such as chemistry or various biological sciences, thus a glossary containing authoritative definitions would be useful for them. The terms used in pharmaceutics are rarely covered by existing glossaries, and in the cases they are, their definitions are often inappropriate for the field of pharmaceutics and require new or modified definitions to better fit the new context.

scholarly journals Stencil Printing—A Novel Manufacturing Platform for Orodispersible Discs

Pharmaceutics ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 33 ◽  
Author(s):  
Henrika Wickström ◽  
Rajesh Koppolu ◽  
Ermei Mäkilä ◽  
Martti Toivakka ◽  
Niklas Sandler
Keyword(s):  
Hydroxypropyl Methylcellulose ◽  
Physicochemical Characterization ◽  
Dosage Forms ◽  
Content Uniformity ◽  
Formulation Development ◽  
Stencil Printing ◽  
Manufacturing Method ◽  
Linear Dose ◽  
Manufacturing Platform

Stencil printing is a commonly used printing method, but it has not previously been used for production of pharmaceuticals. The aim of this study was to explore whether stencil printing of drug containing polymer inks could be used to manufacture flexible dosage forms with acceptable mass and content uniformity. Formulation development was supported by physicochemical characterization of the inks and final dosage forms. The printing of haloperidol (HAL) discs was performed using a prototype stencil printer. Ink development comprised of investigations of ink rheology in combination with printability assessment. The results show that stencil printing can be used to manufacture HAL doses in the therapeutic treatment range for 6–17 year-old children. The therapeutic HAL dose was achieved for the discs consisting of 16% of hydroxypropyl methylcellulose (HPMC) and 1% of lactic acid (LA). The formulation pH remained above pH 4 and the results imply that the drug was amorphous. Linear dose escalation was achieved by an increase in aperture area of the print pattern, while keeping the stencil thickness fixed. Disintegration times of the orodispersible discs printed with 250 and 500 µm thick stencils were below 30 s. In conclusion, stencil printing shows potential as a manufacturing method of pharmaceuticals.

Optimization and Physicochemical Characterization of Chitosan and Chitosan Nanoparticles Extracted from the Crayfish Procambarus clarkii Wastes

2019 ◽  
Vol 38 (2) ◽  
pp. 385 ◽  
Author(s):  
Marwa M. El-Naggar ◽  
Wael S. I. Abou-Elmagd ◽  
Ashraf Suloma ◽  
Hamza A. El-Shabaka ◽  
Magdy T. Khalil ◽  
...  
Keyword(s):  
Procambarus Clarkii ◽  
Chitosan Nanoparticles ◽  
Physicochemical Characterization

Physicochemical Characterization of Solid Dispersions of Cefdinir with PVP K-30 and PEG 4000

2010 ◽  
Vol 3 (2) ◽  
pp. 948-956
Author(s):  
Kumar P ◽  
S Kumar ◽  
A Kumar ◽  
M Chander
Keyword(s):  
Solid Dispersions ◽  
Physicochemical Characterization ◽  
Drug Carriers ◽  
Dissolution Properties ◽  
Rate Of Dissolution ◽  
Peg 4000 ◽  
Release Studies ◽  
Crystalline Nature ◽  
Physical Mixtures

The purpose of this study was to prepare and characterize solid dispersions of the antibacterial agent Cefdinir with PEG 4000 and PVP K-30 with a view to improve its dissolution properties. Investigations of the properties of the dispersions were performed using release studies, X-ray powder diffraction (XRD) and Fourier transform infrared (FTIR). The results obtained showed that the rate of dissolution of Cefdinir was considerably improved when formulated in solid dispersions with PVP K-30 and PEG 4000 as compared with pure drug and physical mixtures. The results from XRD studies showed the transition of crystalline nature of drug to amorphous form, while FTIR studies demonstrated the absence of drug-carriers interaction.

Purification and Physicochemical Characterization of a Trypsin Inhibitor from Cassia absus Linn

2013 ◽  
Vol 21 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Girijesh Patel ◽  
Amit Gupta ◽  
Akshita Gupta ◽  
Manisha Mishra ◽  
Pradhyumna Singh ◽  
...  
Keyword(s):  
Trypsin Inhibitor ◽  
Physicochemical Characterization
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