scholarly journals Effects of Short-Term Treatment with Estrogen Receptor Agonist on Morphological Changes in Reproductive Organs of Adult Male Mice

2016 ◽  
Vol 46 (4) ◽  
pp. 193-200
Author(s):  
Hayana Choi ◽  
Yun Jeong Mo ◽  
Mi-Kyung Lee ◽  
Eun Sang Choe ◽  
Sung Tae Yee ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Adult Male ◽  
Receptor Agonist ◽  
Morphological Changes ◽  
Reproductive Organs ◽  
Term Treatment ◽  
Male Mice ◽  
Short Term ◽  
Short Term Treatment

scholarly journals Short-Term Treatment with Bisphenol-A Leads to Metabolic Abnormalities in Adult Male Mice

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e33814 ◽  
Author(s):  
Thiago M. Batista ◽  
Paloma Alonso-Magdalena ◽  
Elaine Vieira ◽  
Maria Esmeria C. Amaral ◽  
Christopher R. Cederroth ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Adult Male ◽  
Term Treatment ◽  
Metabolic Abnormalities ◽  
Male Mice ◽  
Short Term ◽  
Short Term Treatment

Reproductive toxicity of lapachol in adult male Wistar rats submitted to short-term treatment

2007 ◽  
Vol 21 (7) ◽  
pp. 658-662 ◽  
Author(s):  
Rita de Cássia da Silveira e Sá ◽  
Martha de Oliveira Guerra
Keyword(s):  
Adult Male ◽  
Wistar Rats ◽  
Reproductive Toxicity ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Male Wistar Rats

Adrenal phenotype in TPIT insufficient animals cannot be restored by short-term treatment with physiological doses of ACTH and N-POMC

2005 ◽  
Vol 113 (S 1) ◽  
Author(s):  
S Klammer ◽  
D Schulte ◽  
M Fassnacht ◽  
S Hahner ◽  
AM Pulichino ◽  
...  
Keyword(s):  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment

scholarly journals KIDNEY INJURY MOLECULE-1 AS AN EARLY AMIKACIN-INDUCED NEPHROTOXICITY MARKER IN PATIENTS WITH SEPSIS HOSPITALIZED IN THE INTENSIVE CARE UNIT

2019 ◽  
pp. 277-279
Author(s):  
TRISNI UNTARI DEWI ◽  
INSTIATY . ◽  
RUDIANTO SEDONO ◽  
GESTINA ALISKA ◽  
MUHAMMAD KHIFZHON AZWAR ◽  
...  
Keyword(s):  
Intensive Care ◽  
Kidney Injury ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Safe Level ◽  
Study Results ◽  
Early Biomarker ◽  
Kidney Injury Molecule 1 ◽  
Trough Plasma

Objective: This study sought to determine the correlation between trough plasma amikacin concentrations and urinary normalized kidney injurymolecule-1 (KIM-1) concentrations as an early biomarker of nephrotoxicity in patients with sepsis who are hospitalized in an intensive care unit.Methods: In this pilot study, 12 patients with sepsis were treated with amikacin 1000 mg/day between May 2015 and September 2015. The correlationbetween trough plasma amikacin concentrations measured after the third dose and the elevation of urinary normalized KIM-1 concentrations afterthe third amikacin dose relative to the first/second dose was evaluated.Results: In total, three patients had trough plasma amikacin concentrations exceeding the safe level (>10 μg/ml). Furthermore, eight patientsdisplayed higher normalized KIM-1 concentrations after third dose than after the first/second dose; however, there was no correlation betweentrough amikacin concentrations and the elevation of urinary normalized KIM-1 concentrations (r=0.3, p=0.3).Conclusion: The study results illustrated that short-term treatment with an amikacin dose of 1000 mg/day was generally safe in patients with sepsis.

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