scholarly journals Assessment of Inbreeding Depression and Inbreeding Trend of Production Traits in Iraqi Holstein Cows

Author(s):  
Farzad Moradpour ◽  
Hana Hamidi

Inbreeding is defined as the probability that two alleles at any locus are identical by descent and occur when related individuals are mated to each other. A total of 123427, 115810 and 88361 records of 412-d yields of milk, fat and protein of Iraqi Holstein cows were collected from 1995 to 2010 in 838 herds used to estimation the inbreeding depression and inbreeding trend. Pedigree records of Iraqi Holstein cow were used to assessment inbreeding coefficients and these coefficients ranged from 0 to 42%. Animal model was used to estimation inbreeding depression on traits. Fixed effects included in statistical model were herd – year, age at calving and inbreeding coefficient as continuous and discrete variable. When considering inbreeding as continuous variable in model, the inbreeding depression for 412-d yields of milk, fat and protein were -28.19, -0.98 and -0.88 kg per 1% increase in inbreeding in Iraqi Holsteins, respectively. In this group of animal that inbreeding coefficient was between 0 < F ≤ 5.34 inbreeding was not caused reduction in production traits. However, in group of animal that inbreeding coefficient was greater than 5.34, and inbreeding depression in production traits was observed. The result of this study confirms of inbreeding depression in Iraqi Holstein cows.

2009 ◽  
Vol 52 (1) ◽  
pp. 51-64 ◽  
Author(s):  
A. Köck ◽  
B. Fürst-Waltl ◽  
R. Baumung

Abstract. In this study records of 58 925 litters of Austrian Large White and 17 846 litters of Austrian Landrace pigs were analysed. Regression models were used to determine the effects of litter, dam and sire inbreeding on total number of born, born alive and weaned piglets in Large White and Landrace. In both populations, litter and dam inbreeding showed a negative effect on all traits. Sire inbreeding had no effect in Large White, whereas a significant positive effect was observed in Landrace. On average, inbred sires with an inbreeding coefficient of 10 % had 0.45 more piglets born total and 0.43 more piglets born alive in comparison to non-inbred sires. In a further analysis the total inbreeding coefficients of the animals were divided into two parts: »new« and »old« inbreeding. »New« inbreeding was defined as the period of the first five generations. It was shown that the observed inbreeding effects were not only caused by recent inbreeding. Reproductive performance was also affected by »old« inbreeding. Finally partial inbreeding coefficients of four important ancestors in each population were calculated to investigate if inbreeding effects are similar among these ancestors. The results revealed a varation of inbreeding effects among the four ancestors. Alleles contibuting to inbreeding depression were descendent from specific ancestors.


2020 ◽  
Vol 87 (2) ◽  
pp. 220-225
Author(s):  
Navid Ghavi Hossein-Zadeh ◽  
Hassan Darmani Kuhi ◽  
James France ◽  
Secundino López

AbstractThe aim of the work reported here was to investigate the appropriateness of a sinusoidal function by applying it to model the cumulative lactation curves for milk yield and composition in primiparous Holstein cows, and to compare it with three conventional growth models (linear, Richards and Morgan). Data used in this study were 911 144 test-day records for milk, fat and protein yields, which were recorded on 834 dairy herds from 2000 to 2011 by the Animal Breeding Centre and Promotion of Animal Products of Iran. Each function was fitted to the test-day production records using appropriate procedures in SAS (PROC REG for the linear model and PROC NLIN for the Richards, Morgan and sinusoidal equations) and the parameters were estimated. The models were tested for goodness of fit using adjusted coefficient of determination $\lpar {R_{{\rm adj}}^2 } \rpar $, root mean square error (RMSE), Akaike's information criterion (AIC) and the Bayesian information criterion (BIC). $R_{{\rm adj}}^2 $ values were generally high (>0.999), implying suitable fits to the data, and showed little differences among the models for cumulative yields. The sinusoidal equation provided the lowest values of RMSE, AIC and BIC, and therefore the best fit to the lactation curve for cumulative milk, fat and protein yields. The linear model gave the poorest fit to the cumulative lactation curve for all production traits. The current results show that classical growth functions can be fitted accurately to cumulative lactation curves for production traits, but the new sinusoidal equation introduced herein, by providing best goodness of fit, can be considered a useful alternative to conventional models in dairy research.


2010 ◽  
Vol 55 (No. 3) ◽  
pp. 91-104 ◽  
Author(s):  
K. Yazgan ◽  
J. Makulska ◽  
A. Węglarz ◽  
E. Ptak ◽  
M. Gierdziewicz

The objective of this research was to examine heritabilities and genetic, phenotypic and permanent environmental relationships between milk dry matter (DM) and milk traits such as milk, fat, protein and lactose yields, milk urea nitrogen (MUN) and somatic cell score (SCS) in extended (to 395 days) lactations of Holstein cows from a big farm in Poland. The data set consisted of 78 059 test day records from the first, second and third lactations of 3 792 cows, daughters of 210 sires and 1 677 dams. Single- or two-trait random regression models were used with fixed effects of calving year, calving month, dry period and calving interval and random additive genetic and permanent environmental effects. The last two fixed effects were not included in the analysis of first lactation data. The highest values of heritabilities for all traits, except DM, were observed in the second lactation. First lactation heritabilities for all traits – except milk yield and SCS – were smaller than those in the third lactation. Lactose yield was highly heritable, with average h<SUP>2</SUP> equal to 0.25, 0.29 and 0.28 in lactations 1, 2 and 3, respectively. Heritability for DM was slightly lower than that for lactose (0.22, 0.26 and 0.28 for lactations 1, 2 and 3, respectively). In all lactations heritabilities for SCS were below 0.1. Genetic correlations between DM and milk yield (0.64–0.74) were lower than those between MUN and milk yield (0.67–0.79) as well as between lactose and milk yield (0.72–0.82). In general, DM was much more closely correlated with fat or protein yield (0.55–0.79) than with MUN or lactose (0.38–0.76). Only in the third lactation the correlation between DM and protein (0.72) was lower than between lactose and protein (0.76). For all lactations there were very high genetic correlations between DM and lactose (0.96–0.98) and high correlations between DM and MUN (0.63–0.83) and between lactose and MUN (0.70–0.85). The results suggest that further research is needed, focused on DM and its relationship with other traits in larger populations. &nbsp;


2017 ◽  
Vol 110 (1) ◽  
pp. 37
Author(s):  
Arash CHEGINI ◽  
Navid GHAVI HOSSEIN-ZADEH ◽  
Hossein HOSSEINI-MOGHADAM ◽  
Abdol Ahad SHADPARVAR

<p>The objective of this study was to investigate the effect of somatic cell score (SCS) on milk fat and protein in different parities and stages of lactation in Iranian Holstein cows. Records between June 2003 and January 2014 from 208,478 cows in lactations one to nine in 845 herds, comprising 2,456,303 monthly test-day (TD) records were used. The MIXED procedure of the SAS software with repeated measurements was used. The fixed effects of the model were herd, year-season of calving, month of TD, weeks of lactation, previous dry period length and somatic cell score (SCS) and covariate was calving age. Lactations were divided into six stages and analyses were performed within each stage. Also, different lactations were analyzed separately. Increase of SCS led to increase of milk fat and protein percentage and the increase of milk fat and protein associated with SCS was higher in early stages of lactation relative to later stages of lactation. Also, increase of milk fat and protein associated with SCS was higher in the first lactation rather than later lactations and decreased with increase of parity.</p>


2018 ◽  
Vol 58 (12) ◽  
pp. 2178 ◽  
Author(s):  
P. Mahmoudi ◽  
A. Rashidi ◽  
M. Razmkabir

The objective of this study was to estimate the inbreeding coefficient and its effects on reproductive traits in Markhoz goats. The pedigree file included 5351 kids produced by 234 bucks and 1470 does. Average inbreeding coefficient for the whole population was 2.68%, and the minimum and maximum inbreeding coefficients were 0.05% and 31.25%, respectively. Average coefficient of inbreeding for inbred population was 5.17% and the number of inbred animals in the population was 2777. For investigating effects of inbreeding coefficient on reproductive traits, 3443 records were available for litter size at birth (LSB), litter size at weaning (LSW), total litter weight at birth (TLWB) and mean of litter weight at birth (MLWB). Furthermore, available records for total litter weight at weaning (TLWW) and mean of litter weight at weaning (MLWW) were 2918. Inbreeding depression was estimated as the linear regression of performance on the individual inbreeding coefficient of kids and dams using the most appropriate animal model based on Akaike’s information criterion. Furthermore, inbreeding depressions for LSB and LSW were estimated using threshold and Poisson models. Regression coefficients of LSB, LSW, TLWB, TLWW, MLWB and MLWW on inbreeding coefficient of kids were –0.035, –0.019, –0.077 kg, –0.782 kg, –0.009 kg and –0.332 kg, respectively. Furthermore, regression coefficients of LSB, LSW, TLWB, TLWW, MLWB and MLWW on inbreeding coefficient of dams were 0.064, –0.013, 0.241 kg, 0.638 kg, 0.028 kg and –1.783 kg, respectively. The obtained results from this study showed that inbreeding depression is controlled by an appropriate mating system policy.


1994 ◽  
Vol 58 (2) ◽  
pp. 298-300 ◽  
Author(s):  
K. Christensen ◽  
P. Jensen ◽  
J. N. Jørgensen

Pigs with inbreeding coefficients, ranging from 0·125 to 0·375 were analysed for effect of inbreeding on daily carcass gain, body length and meat proportion in the carcass. The foundation animals were back crosses of a Landrace boar of his daughters which were Yorkshire Landrace hybrids. The statistical model included effect of sex and slaughter weight in addition to the effect of inbreeding. A statistically significant effect of inbreeding on daily carcass gain was found with a linear decline of 1·6 g for 0·1 increase in inbreeding coefficient. There was no effect of inbreeding on body length and meat proportion. Carcass weight had a highly significant effect on body length and daily carcass gain. Effect of sex was statistically significant for meat proportion only.


2021 ◽  
Vol 8 ◽  
Author(s):  
Zhiying Wang ◽  
Bohan Zhou ◽  
Tao Zhang ◽  
Xiaochun Yan ◽  
Yongsheng Yu ◽  
...  

Objective: The purpose of this study was to discover the population structure and genetic diversity of Inner Mongolia White Cashmere goats (IMCGs) and demonstrate the effect of inbreeding on the live body weight (LBW), cashmere yield (CY), fiber length (FL), and fiber diameter (FD) of IMCGs.Materials and Methods: All data were collected from pedigree information and production performance records of IMCGs from 1983 to 2019. The population structure and genetic diversity were analyzed by Endog 4.8 software. Inbreeding coefficients were obtained by the pedigree package in R. Then, a linear regression model was used to analyze how inbreeding influences economic traits in IMCGs. Four levels of inbreeding coefficients (Fi) were classified in this study, including Fi = 0, 0&lt; Fi ≤ 6.25, 6.25&lt; Fi ≤ 12.5 and Fi≥12.5. Variance analysis was performed to determine whether inbreeding levels had a significant effect on economic traits in IMCGs.Results: The proportions of rams and dams in IMCGs for breeding were relatively small, with values of 0.8 and 20.5%, respectively. The proportion of inbred animals in the entire population was high, with values up to 68.6%; however, the average inbreeding coefficient and relatedness coefficient were 4.50 and 8.48%, respectively. To date, the population has experienced 12 generations. The average generation interval obtained in the present study was 4.11 ± 0.01 years. The ram-to-son pathway was lowest (3.97 years), and the ewe-to-daughter pathway was highest (4.24 years). It was discovered that the LBW, CY, and FL increased by 3.88 kg, 208.7 g, and 1.151 cm, respectively, with every 1% increase in the inbreeding coefficient, and the FD decreased by 0.819 μm with every 1% increase in the inbreeding coefficient. Additionally, multiple comparison analysis indicated that when the inbreeding coefficient was higher than 6.25%, the LBW showed an obvious decreasing trend. The threshold value of inbreeding depression in the CY is 12.5%. However, inbreeding depression has not been observed in the FL and FD.Conclusion: Pedigree completeness needs to be further strengthened. The degree of inbreeding in this flock should be properly controlled when designing breeding programs.


2007 ◽  
Vol 2007 ◽  
pp. 63-63
Author(s):  
S. Mc Parland ◽  
J.F. Kearney ◽  
M. Rath ◽  
D.P. Berry

Inbreeding occurs when related individuals are mated to each other. Inbreeding reduces milk production, and impairs health, fertility and survival; a phenomenon known as inbreeding depression. Smith et al. (1998) reported losses in milk yield of 27 kg per 1% increase in inbreeding in US Holsteins. The objective of this study was to investigate the level of inbreeding in Irish Holstein-Friesian cattle and to quantify its effect on milk, fat and protein production and somatic cell count.


2019 ◽  
Vol 59 (6) ◽  
pp. 1031 ◽  
Author(s):  
Arash Chegini ◽  
Navid Ghavi Hossein-Zadeh ◽  
Seyed Hossein Hosseini-Moghadam ◽  
Abdol Ahad Shadparvar

The objective of this study was to estimate genetic parameters including repeatability, heritability as well as genetic and environmental relationships between 305-day milk yield, milk fat and protein yield (Fat and Pro), milk fat and protein percentages (Fat% and Pro%), mastitis (Mast), number of mastitis occurrence and different measurements of somatic cell counts using linear and threshold animal as well as linear and threshold sire models in Holstein cows of Iran. Records of 33851 first lactation Holstein cows from five large dairy herds with calving dates from March 2002 to September 2014 were analysed, using Gibbs sampling methodology. Heritabilities of production traits estimated by linear animal model ranged from 0.14 (Fat%) to 0.29 (Pro%). Generally, udder health traits had low heritability (ranged from 0.005 to 0.10). Estimates of heritability for Mast using linear models were higher than those obtained with threshold models. However, in general estimates of heritabilities using threshold models were higher than those from linear models. There were unfavourable genetic correlations between production traits and Mast, which implies that breeding programs with emphasis on 305-day milk yield will experience deterioration in udder health. Despite low heritability of udder health traits, genetic variability exists for these traits that allow selecting superior animals and increasing resistance to Mast and animal welfare. Considering relatively high ratio of permanent environmental variance for Mast, culling decisions can be made with higher accuracy in order to reduce Mast incidence phenotypically over time.


2020 ◽  
Vol 52 (1) ◽  
Author(s):  
Julia Poyato-Bonilla ◽  
Davinia I. Perdomo-González ◽  
María J. Sánchez-Guerrero ◽  
Luis Varona ◽  
Antonio Molina ◽  
...  

Abstract Background Inbreeding is caused by mating between related individuals and is associated with reduced fitness and performance (inbreeding depression). Several studies have detected heterogeneity in inbreeding depression among founder individuals. Recently, a procedure was developed to predict hidden inbreeding depression load that is associated with founders using the Mendelian sampling of non-founders. The objectives of this study were to: (1) analyse the population structure and general inbreeding, and (2) test this recent approach for predicting hidden inbreeding depression load for four morphological traits and two morphology defects in the Pura Raza Española (PRE) horse breed. Results The regression coefficients that were calculated between trait performances and inbreeding coefficients demonstrated the existence of inbreeding depression. In total, 58,772,533 partial inbreeding coefficients (Fij) were estimated for the whole PRE population (328,706 horses). We selected the descendants of horses with a Fij ≥ 6.25% that contributed to at least four offspring and for which morphological traits were measured for the subsequent analysis of inbreeding depression load (639 horses). A pedigree was generated with the last five generations (5026 animals) used as the reference population (average inbreeding coefficient of 8.39% and average relatedness coefficient of 10.76%). Heritability estimates ranged from 0.08 (cresty neck) to 0.80 (height at withers), whereas inbreeding depression load ratios ranged from 0.01 (knock knee) to 0.40 (length of shoulder), for an inbreeding coefficient of 10%. Most of the correlations between additive and inbreeding depression load genetic values and correlations between inbreeding depression load genetic values for the different traits were positive or near 0. Conclusions Although the average inbreeding depression loads presented negative values, a certain percentage of the animals showed neutral or even positive values. Thus, high levels of inbreeding do not always lead to a decrease in mean phenotypic value or an increase in morphological defects. Hence, individual inbreeding depression loads could be used as a tool to select the most appropriate breeding animals. The possibility of selecting horses that have a high genetic value and are more resistant to the deleterious effects of inbreeding should help improve selection outcomes.


Sign in / Sign up

Export Citation Format

Share Document