Antimicrobial and Anti-inflammatory Activities of Some Marine Brown and Red Algal Species Collected from Safaga Seashore, Red Sea, Egypt

2017 ◽  
Vol 12 (3) ◽  
pp. 1-9
Author(s):  
Neveen Abdel-Raouf ◽  
Hossam Hassan ◽  
Yara Khayri ◽  
Abeer Moawwad ◽  
Waleed Mohamed ◽  
...  
2015 ◽  
Vol 58 (4) ◽  
Author(s):  
Razy Hoffman ◽  
Michael J. Wynne

AbstractThe occurrence of the red algal species


2020 ◽  
Vol 16 (7) ◽  
pp. 1083-1102
Author(s):  
Mohamed A. Shreadah ◽  
Nehad M.A. El Moneam ◽  
Samy A. El-Assar ◽  
Asmaa Nabil-Adam

Background: Aspergillus Versicolor is a marine-derived fungus isolated from Hyrtios Erectus Red Sea sponge. Methods: The aim of this study was to carry out a pharmacological screening and investigation for the in vitro biological activity (antioxidant, cholinergic, antidiabetic and anticancer) of Aspergillus Versicolor crude extract’s active compounds by using different qualitative and quantitative methods. Results: The present study results showed that Aspergillus Versicolor crude extracts contain 0.6 mg total phenolic/mg crude extract. Aspergillus Versicolor also showed a potent antioxidative capacity by decreasing the oxidation of ABTS. The anticancer and inhibitory effects of Aspergillus Versicolor crude extracts on PTK and SHKI were found to be 75.29 % and 80.76%; respectively. The AChE inhibitory assay revealed that Aspergillus Versicolor extracts had an inhibitory percentage of 86.67%. Furthermore, the anti-inflammatory activity using COX1, COX2, TNF, and IL6 was 77.32, 85.21 %, 59.83%, and 56.15%; respectively. Additionally, the anti-viral effect using reverse transcriptase enzyme showed high antiviral activity with 92.10 %. Conclusion: The current study confirmed that the Aspergillus versicolor crude extract and its active constituents showed strong effects on diminishing the oxidative stress, neurodegenerative damage, antiinflammatory, anti-cancer and anti-viral, suggesting their beneficial role as a promising fermented product in the treatment of cancer, oxidative stress, Alzheimer's, anti-inflammatory and anti-viral diseases.


1980 ◽  
Vol 23 (11) ◽  
Author(s):  
Judith L. Connor

AbstractField studies of the benthic macroalgae of fifteen selected Chesapeake Bay oyster communities were conducted over a period of a year (March 1977 to February 1978). Algal distribu tion and seasonal occurrence were studied in relation to changes in the physical environment. Salinity, temperature, and light availability were important factors in the spatial and temporal distributions of algae in these subtidal habitats.Seventeen species of Chlorophyta, Phaeophyta, and Rhodophyta were recorded from the fifteen study sites distributed over 130 kilometers within the Maryland portion of Chesapeake Bay. Species of Chlorophyta were associated with oyster communities throughout the year of study with maximum numbers of species and maximum biomass occurring in spring. Only once was a member of the Phaeophyta encountered; a single filamentous species, Ectocarpus, was collected during winter. Species of Rhodophyta were present throughout the year at the study sites.Most of the algae collected reproduced asexually by spores and/or vegetative fragments. Sexual reproduction occurred in some of the red algal species. The presence of tetrasporic and cystocarpic plants of Dasya baillouviana and Polysiphonia harveyi var. olneyi may indicate that the usual triphasic Florideophycean life history occurs in this estuary.


Marine Drugs ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 38
Author(s):  
Chi-Jen Tai ◽  
Chiung-Yao Huang ◽  
Atallah F. Ahmed ◽  
Raha S. Orfali ◽  
Walied M. Alarif ◽  
...  

Chemical investigation of a Red Sea Spongia sp. led to the isolation of four new compounds, i.e., 17-dehydroxysponalactone (1), a carboxylic acid, spongiafuranic acid A (2), one hydroxamic acid, spongiafuranohydroxamic acid A (3), and a furanyl trinorsesterpenoid 16-epi-irciformonin G (4), along with three known metabolites (−)-sponalisolide B (5), 18-nor- 3,17-dihydroxy-spongia-3,13(16),14-trien-2-one (6), and cholesta-7-ene-3β,5α-diol-6-one (7). The biosynthetic pathway for the molecular skeleton of 1 and related compounds was postulated for the first time. Anti-inflammatory activity of these metabolites to inhibit superoxide anion generation and elastase release in N-formyl-methionyl-leucyl phenylalanine/cytochalasin B (fMLF/CB)-induced human neutrophil cells and cytotoxicity of these compounds toward three cancer cell lines and one human dermal fibroblast cell line were assayed. Compound 1 was found to significantly reduce the superoxide anion generation and elastase release at a concentration of 10 μM, and compound 5 was also found to display strong inhibitory activity against superoxide anion generation at the same concentration. Due to the noncytotoxic activity and the potent inhibitory effect toward the superoxide anion generation and elastase release, 1 and 5 can be considered to be promising anti-inflammatory agents.


2021 ◽  
Vol 75 (2) ◽  
Author(s):  
John M. Huisman ◽  
Roberta D'Archino ◽  
Wendy Nelson ◽  
Sung Min Boo ◽  
Antonella Petrocelli
Keyword(s):  

Antibiotics ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1155
Author(s):  
Areej A. Al-Khalaf ◽  
Hossam M. Hassan ◽  
Aisha M Alrajhi ◽  
Rania Ali El Hadi Mohamed ◽  
Wael N. Hozzein

Background: The Red Sea sponges have been endorsed as a plentiful source of bioactive compounds with promising anti-cancer and anti-inflammatory activities; therefore, exploring their potential as a source of anti-cancer metabolites has stimulated a growing research interest. Purpose: To investigate the anti-cancer and anti-inflammatory potential of the Red Sea sponges, in their bulk and silver nanostructure. Metabolomics analysis of the selected sponge followed by molecular docking studies, will be conducted to explore and predict the secondary metabolites that might provide its capability of inhibiting cancer. Materials and Methods: We prepared a chloroform extract (CE) and ethyl acetate extract (EE) of the Red Sea sponge Phyllospongia lamellosa synthesized silver nanoparticles. The prepared silver nanoparticles were characterized through UV–vis spectrophotometric, transmission electron microscopy (TEM), and Fourier-transform infrared spectroscopy (FTIR) analyses. Testing for their anti-cancer activities was performed against MCF-7, MDB-231, and MCF-10A cells. Anti-inflammatory activity against COX-1 and 2 was assessed. Furthermore, liquid chromatography–mass spectrometry (LC–MS)-based metabolomics analysis and molecular docking were also applied.


2020 ◽  
Vol 71 (13) ◽  
pp. 3827-3842 ◽  
Author(s):  
Anton Puzorjov ◽  
Alistair J McCormick

Abstract The light-harvesting phycobilisome complex is an important component of photosynthesis in cyanobacteria and red algae. Phycobilisomes are composed of phycobiliproteins, including the blue phycobiliprotein phycocyanin, that are considered high-value products with applications in several industries. Remarkably, several cyanobacteria and red algal species retain the capacity to harvest light and photosynthesise under highly selective environments such as hot springs, and flourish in extremes of pH and elevated temperatures. These thermophilic organisms produce thermostable phycobiliproteins, which have superior qualities much needed for wider adoption of these natural pigment–proteins in the food, textile, and other industries. Here we review the available literature on the thermostability of phycobilisome components from thermophilic species and discuss how a better appreciation of phycobiliproteins from extreme environments will benefit our fundamental understanding of photosynthetic adaptation and could provide a sustainable resource for several industrial processes.


Phytotaxa ◽  
2017 ◽  
Vol 302 (1) ◽  
pp. 77 ◽  
Author(s):  
MAURA K. GRIFFITH ◽  
CRAIG W. SCHNEIDER ◽  
DANIEL I. WOLF ◽  
GARY W. SAUNDERS ◽  
CHRISTOPHER E. LANE

Using mitochondrial COI-5P and plastid rbcL genetic markers, the red algal species historically known in southern New England, USA, as Champia parvula is found to be genetically distinct from the species to which it has historically been aligned. This necessitates the description of a new species, C. farlowii, for plants from Rhode Island, Massachusetts, Connecticut and New York, USA. The new species is morphologically compared with true European C. parvula and congeners, especially those with similar features previously aligned under the same species name. Champia farlowii is a morphologically cryptic species, the sixth in the expanding C. parvula complex, with overlapping characteristic measurements despite differences at the range extremes, when compared to C. parvula.


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