scholarly journals Comparison of Effects of Mouthwash Containing Chlorhexidine and Chlorine Dioxide on Salivary Bacteria-A Randomized Control Study

2021 ◽  
pp. 356-362
Author(s):  
Chiranjeevi Vedula ◽  
Harikrishna Reddy Sunkireddy ◽  
Hanusha Bathula ◽  
Chandrika Chinta ◽  
Manasa Akula ◽  
...  
Keyword(s):  
Chlorine Dioxide ◽  
Microbial Load ◽  
Microbial Count ◽  
Distilled Water ◽  
Randomized Control Study ◽  
Intergroup Comparison ◽  
Group A ◽  
Randomized Control ◽  
Group B ◽  
Control Study

Aims: The present study aimed to compare the effectiveness of Chlorhexidine (CHX) and Chlorine dioxide (ClO2) mouthwashes in reducing the microbial load in saliva. Place and Duration of Study: Department of Periodontics, Government Dental College and Hospital, Afzalgunj, Hyderabad, between January and March 2020. Methods and Materials: 60 Patients with gingivitis were included in the study. Ultrasonic scaling was done and saliva samples of the participants were collected and transferred onto blood agar plates. These plates were sent for the microbial count. Later they were given the mouthwash (Chlorhexidine or Chlorine dioxide or Distilled water by random selection) which they used for four weeks. Each group of participants was instructed to rinse 10 ml of 0.2% CHX for one minute twice per day. (Group A) 10 ml of ClO2 (Freshclor) for one minute twice per day. (Group B) 10 ml of Distilled water for one minute twice per day. (Group C) After four weeks of usage of prescribed mouthwashes, the participants were recalled and salivary samples were again collected and sent for the microbial count. Results: The intergroup comparison of CFU between the groups after four weeks showed significant reduction of CFU Groups A and B when compared to Group C. When compared to Group A (CHX), Group B (ClO2) witnessed statistically significant reduction of CFU in with a mean difference of 0.26±0.09 (p<0.001). Conclusion: The present study demonstrated that ClO2 mouth rinse was effective in reducing microbial load after four weeks of usage than CHX.

EFFICACY OF INTRAVENOUS LIGNOCAINE VERSUS TOPICAL LIGNOCAINE IN ATTENUATION OF HAEMODYNAMIC SURGE DURING LARYNGOSCOPY AND INTUBATION IN PATIENTS UNDERGOING SURGERY UNDER GENERALANAESTHESIA - A SINGLE BLIND RANDOMIZED CONTROL STUDY

2021 ◽  
pp. 59-61
Author(s):  
Gautam Piplai ◽  
Amrita Roy ◽  
Dipanjan Dutta ◽  
Sayantan Mukhopadhyay
Keyword(s):  
Elective Surgery ◽  
Haemodynamic Response ◽  
Randomized Control Study ◽  
Group A ◽  
Randomized Control ◽  
American Society ◽  
Group B ◽  
American Society Of Anesthesiologists ◽  
Single Blind ◽  
Control Study

The present study was undertaken to evaluate the efcacy of intravenous lignocaine versus topical lignocaine for attenuating haemodynamic response during laryngoscopy and intubation in patients undergoing surgery under general anaesthesia. This single blind randomized control study was done on sixty patients of either sex aged between 18 to 55 years, of American Society of Anesthesiologists (ASA) status class I undergoing elective surgery under general anesthesia with endotracheal intubation. Patients were randomly allocated into two groups (group A and group B). Group A and Group B received intravenous preservative free lignocaine hydrochloride 2% 2 mg/kg and topical (nebulized) lignocaine hydrochloride 4% at 2mg/kg. Heart rate, systolic, diastolic and mean blood pressure was documented before administering premedication (T0), at time of intubation (TI) and 1 min (T-1), 2 min (T-2) & 5 min (T- 5) after intubation. Attenuation in the HR , SBP, DBP, MBPwere found statistically signicant (P<0.05) in group B in comparison to the group A. So, to conclude, topical lignocaine 4% blunts haemodynamic response to laryngoscopy and intubation better than intravenous lignocaine 2% when other confounding factors are eliminated.

scholarly journals Incidence of post-operative (caesarean section) infectious morbidities in cleansing and non-cleansing group after povidone iodine vaginal cleaning

2021 ◽  
Vol 10 (9) ◽  
pp. 3393
Author(s):  
Pragya Verma ◽  
Dolly Chawla ◽  
Rashmi Khatri ◽  
Preeti Verma
Keyword(s):  
Caesarean Section ◽  
Povidone Iodine ◽  
Medical College ◽  
Lower Segment Caesarean Section ◽  
Significant Difference ◽  
Maternal Morbidity And Mortality ◽  
Group A ◽  
Randomized Control ◽  
Group B ◽  
Control Study

Background: Despite of wide spread use of prophylactic antibiotics and various antiseptic measures, post-operative infection remains one of the significant and serious complication of caesarean delivery contributing to high maternal morbidity and mortality. Objective was to study the incidence of post-operative infectious morbidities in patients with/without povidone iodine vaginal cleansing done prior to caesarean section.Methods: A prospective randomized control study was done in the department of obstetrics and gynecology of Dr. Baba Saheb Ambedkar Medical College and Hospital, New Delhi.Results: Mean age of participants in group A is 26.22±2.47 years and in group B is 26.48±2.3 years. Majority women (84.0%) underwent emergency lower segment caesarean section (LSCS). (6.4%) women developed post-operative endometritis, out of which maximum (4.6%) belong to no vaginal cleansing group (B) compared to 1.8% in povidone iodine vaginal cleansing group(A), which is statistically significant (p=0.01). Over all (13%) women had post-operative fever, with significant difference among the two groups i.e. (8.6%) were in group B versus (4.4%) in group A (p=0.005).Conclusions: Povidone iodine vaginal cleansing prior to caesarean section is significantly effective in reducing post-operative infectious morbidities.

scholarly journals A CASE–CONTROL STUDY TO ASSESS AND COMPARE THE EFFICACY OF 0.2% CHLORHEXIDINE AND 0.25% SODIUM HYPOCHLORITE MOUTHWASH IN TREATMENT OF CHRONIC GINGIVITIS

2018 ◽  
Vol 11 (5) ◽  
pp. 313 ◽  
Author(s):  
Kaavya Shanker ◽  
Girish Suragimath ◽  
Sameer A Zope ◽  
Siddhartha A Varma ◽  
Ashwinirani Sr
Keyword(s):  
Sodium Hypochlorite ◽  
Case Control Study ◽  
Study Groups ◽  
Gingival Index ◽  
Gingival Inflammation ◽  
Intergroup Comparison ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Control Study

Objective: The objective of present study was to compare the efficacy of 0.2% chlorhexidine and 0.25% sodium hypochlorite as a mouthwash in controlling chronic gingivitis.Methods: A total of 80 patients suffering from chronic marginal gingivitis were recruited for the study. Non-surgical periodontal therapy was completed for all the patients to bring the gingival status to healthy levels. The patients were divided into two study groups with 40 patients in each group, Group A patients were asked to use 0.2% chlorhexidine mouthwash, and Group B patients used 0.25% sodium hypochlorite mouthwash as an adjunct to brushing twice daily for 2 weeks. After a period of 2 weeks, the gingival status was recorded using the oral hygiene index simplified (OHIS), plaque index (PI), and modified gingival index (MGI) and compared between the two groups.Results: The mean OHIS score for Group A was 1.38 and for Group B it was 1.05. The mean PI for Group A and B was 3.62 and 2.32, respectively. The mean MGI score for Group A was 1.22 and for Group B was 1.20. Group B showed better results than Group A. Intergroup comparison of OHIS and PI revealed significantly better results in Group B than Group A while MGI did not show any statistical difference on comparison.Conclusion: Nearly 0.25% sodium hypochlorite was more effective than 0.2% chlorhexidine in reducing the gingival inflammation. Thus, 0.25% sodium hypochlorite may represent an efficacious, safe and affordable antimicrobial agent in the prevention and treatment of gingival disease.

scholarly journals LASIK-induced Corneal Changes after Correction of Hyperopia with and without Application of Mitomycin-C

2019 ◽  
Author(s):  
Ehab M. Moawad ◽  
Ahmed A. Abd Elghany ◽  
Amr A. Gab-Alla ◽  
Osama M. Elbassiouny ◽  
Mohsen S. Badawy
Keyword(s):  
Mitomycin C ◽  
Clinical Trial Registry ◽  
Uncorrected Distance Visual Acuity ◽  
Group A ◽  
Randomized Control ◽  
One Year ◽  
Group B ◽  
Control Study

Abstract Background The study aimed to assess the role of intraoperative mitomycin-C (MMC) application during hyperopic LASIK correction (+1.00 D to +6.00 D) by examining topographic corneal changes and incidence of regression over a one-year follow-up period. Methods This comparative randomized control study included 136 eyes of 68 hyperopic patients divided into two groups; Group A included 68 eyes of 34 patients that had LASIK with the application of 0.02% MMC for 10 seconds on the stromal bed after excimer laser treatment, and group B included 68 eyes of 34 patients that had LASIK without MMC application. Uncorrected distance visual acuity (UDVA), refraction, keratometry and topography were recorded at 1st week and 1st, 3rd, 6th, and 12th months postoperation. Predictability and treatment efficacy were also recorded at the end of the follow-up period. Results Better predictability was noted in group A than in group B at the 6 month and 12 month follow-up visits, with a mean cycloplegic refraction SE of +0.5 ± 0.31 D in group A and +0.67 ± 0.39 D in group B at the 6 month visit, and +0.63 ± 0.37 D in group A and +0.89 ± 0.48 D in group B at the 12 month visit. The efficacy of the treatment at the end of the follow up period was better in group A than in group B. Group A showed fewer topographic corneal changes than group B. Conclusions Intraoperative MMC application during hyperopic LASIK achieves better predictability and efficacy and induces fewer topographic changes and lower regression rate of hyperopia during the first postoperative year. Trial registration: the Pan African Clinical Trial Registry PACTR201901543722087, on 29 January 2019.

scholarly journals LASIK-induced Corneal Changes after Correction of Hyperopia with and without Application of Mitomycin-C

2019 ◽  
Author(s):  
Ehab M. Moawad ◽  
Ahmed A. Abd Elghany ◽  
Amr A. Gab-Alla ◽  
Osama M. Elbassiouny ◽  
Mohsen S. Badawy
Keyword(s):  
Mitomycin C ◽  
Clinical Trial Registry ◽  
Uncorrected Distance Visual Acuity ◽  
Group A ◽  
Randomized Control ◽  
One Year ◽  
Group B ◽  
Control Study

Abstract Background The study aimed to assess the role of intraoperative mitomycin-C (MMC) application during hyperopic LASIK correction (+1.00 D to +6.00 D) by examining topographic corneal changes and incidence of regression over a one-year follow-up period. Methods This comparative randomized control study included 136 eyes of 68 hyperopic patients divided into two groups; Group A included 68 eyes of 34 patients that had LASIK with the application of 0.02% MMC for 10 seconds on the stromal bed after excimer laser treatment, and group B included 68 eyes of 34 patients that had LASIK without MMC application. Uncorrected distance visual acuity (UDVA), refraction, keratometry and topography were recorded at 1st week and 1st, 3rd, 6th, and 12th months postoperation. Predictability and treatment efficacy were also recorded at the end of the follow-up period. Results Better predictability was noted in group A than in group B at the 6 month and 12 month follow-up visits, with a mean cycloplegic refraction SE of +0.5 ± 0.31 D in group A and +0.67 ± 0.39 D in group B at the 6 month visit, and +0.63 ± 0.37 D in group A and +0.89 ± 0.48 D in group B at the 12 month visit. The efficacy of the treatment at the end of the follow up period was better in group A than in group B. Group A showed fewer topographic corneal changes than group B. Conclusions Intraoperative MMC application during hyperopic LASIK achieves better predictability and efficacy and induces fewer topographic changes and lower regression rate of hyperopia during the first postoperative year. Trial registration: the Pan African Clinical Trial Registry PACTR201901543722087, on 29 January 2019.

scholarly journals LASIK-induced Corneal Changes after Correction of Hyperopia with and without Application of Mitomycin-C

2019 ◽  
Author(s):  
Ehab M. Moawad ◽  
Ahmed A. Abd Elghany ◽  
Amr A. Gab-Alla ◽  
Osama M. Elbassiouny ◽  
Mohsen S. Badawy
Keyword(s):  
Mitomycin C ◽  
Clinical Trial Registry ◽  
Uncorrected Distance Visual Acuity ◽  
Group A ◽  
Randomized Control ◽  
One Year ◽  
Group B ◽  
Control Study

Abstract Background The study aimed to assess the role of intraoperative mitomycin-C (MMC) application during hyperopic LASIK correction (+1.00 D to +6.00 D) by examining topographic corneal changes and incidence of regression over a one-year follow-up period. Methods This comparative randomized control study included 136 eyes of 68 hyperopic patients divided into two groups; Group A included 68 eyes of 34 patients that had LASIK with the application of 0.02% MMC for 10 seconds on the stromal bed after excimer laser treatment, and group B included 68 eyes of 34 patients that had LASIK without MMC application. Uncorrected distance visual acuity (UDVA), refraction, keratometry and topography were recorded at 1st week and 1st, 3rd, 6th, and 12th months postoperation. Predictability and treatment efficacy were also recorded at the end of the follow-up period. Results Better predictability was noted in group A than in group B at the 6 month and 12 month follow-up visits, with a mean cycloplegic refraction SE of +0.5 ± 0.31 D in group A and +0.67 ± 0.39 D in group B at the 6 month visit, and +0.63 ± 0.37 D in group A and +0.89 ± 0.48 D in group B at the 12 month visit. The efficacy of the treatment at the end of the follow up period was better in group A than in group B. Group A showed fewer topographic corneal changes than group B. Conclusions Intraoperative MMC application during hyperopic LASIK achieves better predictability and efficacy and induces fewer topographic changes and lower regression rate of hyperopia during the first postoperative year. Trial registration: the Pan African Clinical Trial Registry PACTR201901543722087, on 29 January 2019.

scholarly journals VIDEO TURP: SURPASSING THE GOLD STANDARD

1969 ◽  
Vol 2 (1) ◽  
pp. 96-99
Author(s):  
Liaqat Ali ◽  
Mir Alam Jan ◽  
Sarhad Khan ◽  
Khursheed Anwar
Keyword(s):  
P Value ◽  
Medical Sciences ◽  
New Approach ◽  
Bladder Irrigation ◽  
Group A ◽  
Key Words Prostate ◽  
The Mean ◽  
Randomized Control ◽  
Group B ◽  
Control Study

Objectives: To compare the resection time and resected volume of the prostate in patients who weresubjected to video Trans-urethral resection of prostate (TURP) and conventional TURP, and to determinethe difference in the duration of bladder irrigation during post-operative period for conventional TURP andvideo TURP. Study Design: Comparative randomized control study. Methods: The study was conducted in the Department of Urology at Pakistan Institute of Medical Sciences(PIMS) Islamabad from Is' March 2002 to 28,h February 2003. Total number of 100 patients were equally Kdivided into two groups. Group ’A’ comprising of 50 patients (Control) were subjected to ConventionalTURP and Group 'B' comprising of 50 patients (Case) were subjected to video TURP respectively. Thesample was randomized by the last digit of the hospital admission number, Even number was allocated togroup 'A' and Odd number to group 'B'. The data was recorded on structured proforma and was analyzed onSPSS. ' ; Results: The mean age of the patients was 65.5 years with the range of 42-96 years. The Mean resection timefor conventional TURP was 36.03 minutes and for video TURP was 37.27 minutes ( P value = 0.068 ). Themean resected volume for conventional TURP was 18.5 gm and for video TURP was 23.65gm ( P value =0.01 ). The post operative irrigation of the bladder with 0.9% saline was required for 3.32 days inconventional TURP, while it was required for 1.57 days in video TURP ( P < 0.05 ). There was no TURPsyndrome recorded in both the groups and the mean hospital stay for both the group was equal i.e. 4th Postoperative day as per protocol of our department. Conclusion: The video TURP has opened up a new Approach in endourology. It is more effective inresection than conventional TURP and bears the same safety of resection time as conventional TURP. Key Words: Prostate,TURP, Endourology, Video TURP

scholarly journals A comparative study of conjunctival autograft with fibrin glue or glueless sutureless conjunctival autograft after pterygium surgery

2018 ◽  
Vol 6 (2) ◽  
pp. 557
Author(s):  
Kalpna Jain ◽  
J. M. Manoher
Keyword(s):  
Fibrin Glue ◽  
Cost Effective ◽  
P Value ◽  
Conjunctival Autograft ◽  
Group A ◽  
Pterygium Surgery ◽  
Randomized Control ◽  
Group B ◽  
Control Study ◽  
Conjunctival Autografting

Background: Conjunctival autografting after Pterygium excision can be done by fibrin glue or sutures but use of foreign material can cause discomfort and infection. Fibrin glue may cause hypersensitivity reaction and also have risk of viral transmission. To avoid these conjuctival autograft can be applied without suture or glue. Patient’s own blood act as a bioadhesive.Methods: We done a prospective randomized control study of 70 patients, 35 patients allocated in each group. Group A had conjunctival autograft with fibrin glue while group B had conjunctival autografting without glue or sutures.Results: In group A 31 and group B 26 patients had well placed conjunctival autograft while 4 in group A and 9 patients in group B had either displaced or dislodged graft. The results were statistically insignificant with P value of 0.219 and No complication was reported in any patient except recurrence. The 5 patients in group A and 6 in group B had recurrence which is not statistically significant.Conclusions: Graft stability is more with fibrin glue as compare to glueless and sutureless conjunctival autografting but using patients own blood as bioadhesive is safer and cost effective. The rate of recurrence is similar in both the groups.

202-OR: Basal Insulin Digital Titration App vs. Enhanced Paper Titration Tool: A Randomized Control Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 202-OR
Author(s):  
ATHENA PHILIS-TSIMIKAS ◽  
ADDIE L. FORTMANN ◽  
ALESSANDRA BASTIAN ◽  
ARATI KANCHI ◽  
RICARDO ABAD ◽  
...  
Keyword(s):  
Basal Insulin ◽  
Randomized Control Study ◽  
Randomized Control ◽  
Control Study
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