scholarly journals Clinicopathological Study of Uterine Leiomyomas – A Retrospective Study

Author(s):  
Mahati Sundar ◽  
Chitra Srinivasan

Leiomyomas are benign tumors of the uterus affecting women of the reproductive age group. They are the most common gynaecologic neoplasms in women. The aim of our study was to analyse and correlate the histopathological findings of leiomyomas in 203 hysterectomy specimens received in the department of Pathology at Saveetha Medical College and to further delineate the associated changes and variants that were observed in the leiomyoma specimens. In this study we found that the dominant age group was 31-50 years of age with multiple leiomyomas being more common than solitary ones. The most commonly observed location was intramural. Majority of the hysterectomy specimens showed a proliferative pattern of endometrium. Degenerative changes were observed in 26 cases with hyaline degeneration being the most common secondary change. There were multiple uterine pathologies associated with the uterine leiomyomas of which ovarian cortical cysts were the most frequently noted. The histopathological study of leiomyomas is important as it helps to further ascertain the diagnosis and ensure optimal patient management.

Author(s):  
Manpreet Kaur ◽  
Rajiv Kamal Gupta ◽  
Simrat Jit Kaur ◽  
Panchampreet Kaur

Background: Leiomyomas are benign tumors of smooth muscle cells commonly encountered in women of reproductive age group. Aim of this study was to conduct a histopathological study of leiomyomas in hysterectomy specimens and to correlate them with clinical findings.Methods: A prospective study was done on 130 hysterectomy specimens clinically diagnosed as leiomyoma. The specimens were subjected to histopathological examination.Results: In this study, the most common age group was 31-50 years (87.69%). Most common complaint was menorrhagia (51.54%). In endometrium, the most common histopathological diagnosis was proliferative phase (46.15%) followed by endometrial hyperplasia (19.23%). The most common secondary change was hyalinization and the most common site was intramural (62.9%).Conclusions: Hysterectomy is a commonly performed procedure in the management of uterine leiomyomas. The ultimate diagnosis and prognosis depends on the histopathological examination; therefore, every operated specimen must be subjected to histopathology. 


Author(s):  
Kanchan Digambar Bhoyar ◽  
Sakshi Abhinav Zawar ◽  
Abhijit Sharachandra Ambike ◽  
Unmesh Sureshrao Santpur ◽  
Vijay Dhundiraj Dombale

To report the occurrence of a rare case of a huge benign ovarian tumour (mucinous cystadenoma) in in a tertiary care rural teaching hospital in Konkan, Maharashtra, India. Our reported case was a young woman of reproductive age group which was very rare who presented with marked abdominal distension and discomfort at the obstetrics-gynaecology OPD of BKL Walavalkar rural medical college. The data were collected by history-taking, clinical examination, laboratory investigations, transabdominal ultrasonographic examination and by histopathological study of the excised surgical specimen. The case was reported as a rare massive ovarian mucinous cystadenoma in a woman of reproductive age group. This case report emphasized the significance of thorough evaluation of all women presented with vague abdominal pain and gradual abdominal distension in reproductive age group. Although the condition is extremely rare, women from rural area neglect such conditions and present late which may pose challenges in the management.


2021 ◽  
pp. 37-39
Author(s):  
Teleflo Boopathy ◽  
Gowri Prakasam ◽  
T.M Vincy ◽  
Dharshini. G.V

BACKGROUND: Leiomyoma is one of the most common causes of Abnormal Uterine Bleeding. It occurs chiey in women during active reproductive years. It has a lot of morphological variants and secondary changes which may mimic malignancy clinically, radiologically and histologically. A few degenerative changes and variants like Atypical and Mitotically active Leiomyoma may be misdiagnosed as malignancy. It is imperative to have a good knowledge of Leiomyosarcoma as the treatment protocol varies. AIMS AND OBJECTIVES: To analyse the morphological variants and secondary changes in Leiomyoma and to study the associated changes in the endometrium. MATERIALS AND METHODS: 420 Hysterectomy specimens with Fibroid received at Govt. Kilpauk medical College, Chennai were studied from January 2018 to January 2020. RESULTS: Leiomyoma was seen in the reproductive age group and menorrhagia was the most common clinical presentation. Hyalinisation was the most common secondary change seen in Leiomyoma and cellular leiomyoma was the most common morphological variant. CONCLUSION:A good comprehensive and accurate knowledge of the morphological variants and secondary changes in Leiomyoma mandatory to avoid misdiagnosis and ensuring optimal patient management.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Eliza Ranjit ◽  
Bijendra Raj Raghubanshi ◽  
Smrity Maskey ◽  
Pramila Parajuli

Bacterial vaginosis (BV) is an ecological imbalance of the vaginal microbiota affecting mostly women of reproductive age group. This study was carried out among 160 nonpregnant women registered at the Outpatient Department of Gynaecology/Obstetrics of KIST Medical College Teaching Hospital, Imadol, Lalitpur, Nepal, from November 2014 to May 2015. The aim of the study was to assess the association of the risk factors with BV and analyze the type of bacteria associated with BV. Nugent’s scoring method was used for diagnosis of BV in this study. The overall prevalence of BV was 24.4% among symptomatic patients. Douching was statistically related to BV(P=0.015). Also, BV was significantly associated with consistency(P=0.0001), odor(P=0.02), and amount of abnormal vaginal discharge(P=0.09). Contraceptives users on anatomical sites were found more prone to BV than those who did not use contraceptives on anatomical sites.Pseudomonasspp.,Escherichia coli, Acinetobacterspp., Proteusspp., Klebsiellaspp., Neisseria gonorrhoeae, Enterobacterspp., Citrobacterspp., Staphylococcus aureus,Coagulase-Negative Staphylococci (CoNS),andStreptococcus agalactiaewere associated with BV and out of thoseLactobacillusspp. was the predominant organism. The higher prevalence of BV among symptomatic patients indicates interventions should be applied to reduce the incidence of stillbirth, abortion, and sterility.


Author(s):  
Om Prakash Raichandani ◽  
Abhijeet Kadam ◽  
Sapna Raichandani

The study was performed at the Department of Pharmacology in collaboration with Department of Psychiatry, NSCB Medical College, Jabalpur. The maximum numbers of patients in were in reproductive age group that is in between 20 to 49 years. The mean age in Amisulpride group was 33.26(±10.23) years while in Olanzapine group it was 31.25 (±12.22) years. Schizophrenia was more common (80%) in younger (20-49years) age group. In our study the male /female ratio was 1.7. Our study supports the notion that Schizophrenia is more common in Married and Urban population. Only one patient from Olanzapine  Group suffered  Extrapyramidal  symptoms of  moderate severity requiring  withdrawal from study.2  patients  from Olanzapine group and 1 patient from Amisulpride group  had Tremors and Akathesia  of mild severity. There was no emergence of Extrapyramidal symptoms in rest of the patients (p>.05) Keywords: Efficacy, Amisulpride, Olanzapine & Schizophrenia.


2018 ◽  
Vol 9 (1) ◽  
pp. 50-56
Author(s):  
Sazia Huq ◽  
Syed Mohammad Tanjilul Haque ◽  
Md Atiqur Rahman ◽  
Farzana Mahmuda ◽  
Maeda Mahjabein

Background: In Bangladesh the neonatal mortality rate is unacceptably high, at 48.4 per 1,000 live births and it is higher in rural areas while the neonatal mortality rate in Asia is 41 per 1,000 live-births, compared to 7 per 1,000 live-births in developed countries.Materials & Methods: This descriptive type of cross sectional study was carried out among 180 rural mothers of reproductive age in Mymensingh Medical College Hospital, Mymensingh from October 2013 to January 2014. Data were collected on a pretested questionnaire by face to face interview.Results: The study revealed that 50.6% of the respondents were housewife & education wise 42.2% had primary education with mean age 26.28±5.50 years. 61% respondents knew that cord should be cut by sterile blade and 65% respondents mentioned that cord should be cut immediate after delivery. Among them 44.4% knew about initiation of breast feeding within 1st hour of delivery, 71.1% believed the importance of colostrums feeding. Only 30% of the respondents knew about frequency of breast feeding to the baby should be 8-10 times in a day and 58% had knowledge on exclusive breast feeding. Of the respondents 52.2% went for exclusive breast feeding but others did not. 67% respondents immunized their baby whereas 33% did not. More than half of the respondents (59%) cleaned their breast before feeding and 80.6% respondents washed their hands before handling their newborn. A significant association was found between education and knowledge on immunization of newborn (P=0.000), education and exclusive breast feeding (P=0.003).Conclusion: The current study may boost up the awareness among rural mothers of reproductive age group on neonatal care which will further encourage them to be educated and thus neonatal morbidity & mortality may decline in some extent.Anwer Khan Modern Medical College Journal Vol. 9, No. 1: Jan 2018, P 50-56


2021 ◽  
Vol 6 (2) ◽  
pp. 170-174
Author(s):  
Murat Celiloglu ◽  
◽  
Samican Ozmen ◽  
Sefa Kurt ◽  
Orkun Ilgen

Uterine fibroids are the most common benign tumors in women in the reproductive age group. The incidence of fibroids during pregnancy varies between 1.6 and 10.7%. In 10% of these cases, fibroids lead to complications. The management in symptomatic patients is conservative, and the surgical treatment is delayed until after birth due to its risks. In the last two decades, it has been shown that myomectomy can be an alternative treatment in selected cases, especially in second-trimester pregnancies. However, the data on the success of myomectomies performed earlier in pregnancy are limited. In this case report, we present two cases who were admitted to our clinic during the first trimester of pregnancy and had complicated fibroids. The diagnosis, the follow up and the treatment are presented with the review of the literature.


Author(s):  
Kritika Agrawal ◽  
Shubhangi Mande ◽  
Lakshmi Rachakonda

Worldwide 20-30% of labour cases are induced. We conducted an analysis to evaluate the success of labour induction for indicated preterm birth A prospective observational study was conducted among 50 patients admitted in the Department of OBGY, MGM Medical College and Hospital, Aurangabad from 1st March 2019 to 31st March 2020. There was a total of 50 deliveries during this period. The preterm induction majorly includes 20-34 years as this is the commonest reproductive age group seen in our hospital. More number of Hindus underwent induction. Multigravida requires induction more as compared to primigravida. More number of patients were induced between 32-36 weeks, reason being PPROM, severe preeclampsia, IUD and severe FGR. Vaginal delivery is more likely irrespective of bishop score. Induction of labour remains relevant obstetrics procedure and its outcome will depend on proper choice of patients and close intrapartum monitoring


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