scholarly journals TO STUDY EFFICACY OF AMISULPRIDE IN TREATMENT OF SCHIZOPHRENIA.

Author(s):  
Om Prakash Raichandani ◽  
Abhijeet Kadam ◽  
Sapna Raichandani

The study was performed at the Department of Pharmacology in collaboration with Department of Psychiatry, NSCB Medical College, Jabalpur. The maximum numbers of patients in were in reproductive age group that is in between 20 to 49 years. The mean age in Amisulpride group was 33.26(±10.23) years while in Olanzapine group it was 31.25 (±12.22) years. Schizophrenia was more common (80%) in younger (20-49years) age group. In our study the male /female ratio was 1.7. Our study supports the notion that Schizophrenia is more common in Married and Urban population. Only one patient from Olanzapine  Group suffered  Extrapyramidal  symptoms of  moderate severity requiring  withdrawal from study.2  patients  from Olanzapine group and 1 patient from Amisulpride group  had Tremors and Akathesia  of mild severity. There was no emergence of Extrapyramidal symptoms in rest of the patients (p>.05) Keywords: Efficacy, Amisulpride, Olanzapine & Schizophrenia.

2017 ◽  
Vol 3 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Md Shafiul Alam ◽  
Md Abdus Salam ◽  
Tayseer Farzana ◽  
ASM Raushan Newaz ◽  
Md Saiful Islam

Background: Spinal tuberculosis is more frequently reported in developing countries.Objective: The purpose of the present study was to see the socio-demographic characteristics of spinal tuberculosis patients.Methodology: This study was carried out in the Department of Neurosurgery, Dhaka Medical College Hospital during the period of January 2002 to December 2004 to elucidate the effectiveness of surgical and conservative treatment of the tuberculosis of the spine. For this purpose, a total number of 50 consecutive cases admitted during the study period with tuberculosis of the spine supported by investigations were included in this study.Result: The mean age of the patients was 25.4 years and ranged from 7 years to 68 years. The highest incidence of tuberculosis of the spine was found in age group between 11 to 20 years and 70% of the patients were under 30 years of age. Incidence of tuberculosis of this spine was more in male (62%) in comparison to female (3 8%) with a male female ratio of 1.63:1. In this study most of the patients came from low class society (66%) followed by middle class (28%) and high class (6%) respectively.Conclusion: Spinal TB more frequently occurs among the young age group with a male predominance.Bangladesh Journal of Infectious Diseases 2016;3(1):3-5


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Eliza Ranjit ◽  
Bijendra Raj Raghubanshi ◽  
Smrity Maskey ◽  
Pramila Parajuli

Bacterial vaginosis (BV) is an ecological imbalance of the vaginal microbiota affecting mostly women of reproductive age group. This study was carried out among 160 nonpregnant women registered at the Outpatient Department of Gynaecology/Obstetrics of KIST Medical College Teaching Hospital, Imadol, Lalitpur, Nepal, from November 2014 to May 2015. The aim of the study was to assess the association of the risk factors with BV and analyze the type of bacteria associated with BV. Nugent’s scoring method was used for diagnosis of BV in this study. The overall prevalence of BV was 24.4% among symptomatic patients. Douching was statistically related to BV(P=0.015). Also, BV was significantly associated with consistency(P=0.0001), odor(P=0.02), and amount of abnormal vaginal discharge(P=0.09). Contraceptives users on anatomical sites were found more prone to BV than those who did not use contraceptives on anatomical sites.Pseudomonasspp.,Escherichia coli, Acinetobacterspp., Proteusspp., Klebsiellaspp., Neisseria gonorrhoeae, Enterobacterspp., Citrobacterspp., Staphylococcus aureus,Coagulase-Negative Staphylococci (CoNS),andStreptococcus agalactiaewere associated with BV and out of thoseLactobacillusspp. was the predominant organism. The higher prevalence of BV among symptomatic patients indicates interventions should be applied to reduce the incidence of stillbirth, abortion, and sterility.


2018 ◽  
Vol 19 (2) ◽  
pp. 92
Author(s):  
Md Sunny Anam Chowdhury ◽  
Sadia Sultana ◽  
Md Abdul Awal ◽  
Suraya Sarmin ◽  
Mohammad Simoon Salekin

<p><strong>Objective</strong>: This interventional study has undertaken to assess the gonadal function of differentiated thyroid cancer (DTC) patients within reproductive age group following single dose of radioactive iodine (131I) therapy/ablation.</p><p><strong>Patients and Methods:<em> </em></strong>A total of 69 patients (25 male and 44 female) of DTC were included in this study, those were referred for 131I ablation after total thyroidectomy. Following RAI, these patients were followed-up three times at three months interval.  The usual I-131 dose was 75 or 100 m Ci for ablation of thyroid residues and 150 mCi for treatment of nodal metastasis. All the patients were interviewed about menstrual (female only) and reproductive history and investigated of the level of follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone of male patients and FSH, LH, estradiol (E<sub>2</sub>) of female patients before administration of  131I and three, six and nine months after therapy.</p><p><strong>Result</strong>: In this study all of the 25 (100.0%) male patients showed high FSH level after three months of therapy. The mean± SD FSH level of male patients was found significantly (p-0.001) higher (15.59±7.53 IU/L) after three months of therapy than the pretherapy (4.85±2.57 IU/L) level.  The mean± SD of FSH level was significantly declining in six months and nine months of follow up. The mean± SD of LH hormone level of these patients was found 6.1±3.67 IU/L in pretherapy which was significantly increased to 7.67±4.33 IU/L after three months. The mean LH level was 7.20±3.98 IU/L at six months follow up and 7.3±3.5IU/L after nine months. The differences of LH level between 3 months to 6 months and 6 months to 9 months are not statistically significant. No significant change was observed in testosterone level throughout the study period. In female, five patients developed irregular menstruation (changed duration of cycle or lighter amount), three patients developed amenorrhea associated with hot flashes within six months of 131I administration. Biochemical study of the patients with amenorrhoea showed markedly elevated serum FSH, LH level and declined E<sub>2 </sub>level. The FSH, LH levels of the two patients with amenorrhea became normal within study period and one patient had persistent amenorrhea at 9 months. E<sub>2</sub> level raised slowly.</p><p><strong>Conclusion</strong>: A single dose of radio-iodine (131I) therapy causes impairment of gonadal function of male patients within reproductive age group. In case of female patients the effect is insignificant. The effect is usually reversible and gonadal function of the patients restores within the study period.</p><p>Bangladesh J. Nuclear Med. 19(2): 92-97, July 2016  </p>


2015 ◽  
Vol 22 (06) ◽  
pp. 798-803
Author(s):  
Mariam Arif

Introduction: There are three types of compression of neck which are of primeforensic importance – (1) Manual strangulation (2) Hanging (3) Ligature strangulation. Ligaturemark is found in the latter two types.1 Ligature mark is a pressure mark on the neck underneaththe ligature. Initially it appears as a pale groove which on drying becomes yellowish brownparchment like.2,5 Objective: The aim is to study the information provided by a ligature markin ligature asphyxial deaths. Methodology: Study Design: A retrospective study on ligatureasphyxial deaths. Setting: Forensic Medicine and Toxicology Departments of King EdwardMedical University, Lahore and Nishtar Medical College, Multan. Period: January, 2012 toDecember, 2013. Results: The incidence of violent ligature asphyxial deaths was 4.21% of thetotal medicolegal deaths autopsied. Age group 21 to 30 years accounted for the maximumcases (37.6%). Male: female ratio was 1.02. Nylon rope (44.7%) was the most common ligaturematerial used. Ligature mark was single in all cases and was situated above thyroid cartilage in82.92% cases of hanging. In ligature strangulation deaths, mark was one in number in 93.18%cases and was below thyroid cartilage in 97.72% cases. The manner of death in hangingwas mostly suicidal (90.24%) as compared to homicidal in all cases of ligature strangulation.Ligature mark was incompletely encircling the neck in 85.36% cases and obliquely present in100% cases of hanging. In all deaths due to ligature strangulation, it was completely encirclingand transversely present around the neck. Underlying soft tissues of neck were glisteningwhite in all hanging deaths while it showed extravasations of blood in all ligature strangulationcases. Conclusions: A meticulous examination of the ligature mark during autopsy, though notconclusive, can give valuable information that can be very helpful in diagnosing deaths due tohanging and ligature strangulation.


2018 ◽  
Vol 9 (1) ◽  
pp. 50-56
Author(s):  
Sazia Huq ◽  
Syed Mohammad Tanjilul Haque ◽  
Md Atiqur Rahman ◽  
Farzana Mahmuda ◽  
Maeda Mahjabein

Background: In Bangladesh the neonatal mortality rate is unacceptably high, at 48.4 per 1,000 live births and it is higher in rural areas while the neonatal mortality rate in Asia is 41 per 1,000 live-births, compared to 7 per 1,000 live-births in developed countries.Materials & Methods: This descriptive type of cross sectional study was carried out among 180 rural mothers of reproductive age in Mymensingh Medical College Hospital, Mymensingh from October 2013 to January 2014. Data were collected on a pretested questionnaire by face to face interview.Results: The study revealed that 50.6% of the respondents were housewife & education wise 42.2% had primary education with mean age 26.28±5.50 years. 61% respondents knew that cord should be cut by sterile blade and 65% respondents mentioned that cord should be cut immediate after delivery. Among them 44.4% knew about initiation of breast feeding within 1st hour of delivery, 71.1% believed the importance of colostrums feeding. Only 30% of the respondents knew about frequency of breast feeding to the baby should be 8-10 times in a day and 58% had knowledge on exclusive breast feeding. Of the respondents 52.2% went for exclusive breast feeding but others did not. 67% respondents immunized their baby whereas 33% did not. More than half of the respondents (59%) cleaned their breast before feeding and 80.6% respondents washed their hands before handling their newborn. A significant association was found between education and knowledge on immunization of newborn (P=0.000), education and exclusive breast feeding (P=0.003).Conclusion: The current study may boost up the awareness among rural mothers of reproductive age group on neonatal care which will further encourage them to be educated and thus neonatal morbidity & mortality may decline in some extent.Anwer Khan Modern Medical College Journal Vol. 9, No. 1: Jan 2018, P 50-56


Author(s):  
Anchal Gupta ◽  
Palak Gupta ◽  
Padam Singh Jamwal

<p class="abstract"><strong>Background:</strong> Septoplasty is one the most commonly performed surgery in ENT. The aim of this study was to evaluate change in voice after septoplasty using voice handicap index (VHI).</p><p class="abstract"><strong>Methods:</strong> The current study was conducted at Department of ENT, SMGS Hospital, Government Medical College, Jammu, from October 2017 to November 2018. The study population was the patients who had come to the department with deviated nasal septum admitted for septoplasty. Voice assessment was done by Subjective Voice evaluation using VHI. It was done at three times i.e. preoperatively, postoperatively at 1 week and then postoperatively at 1 month.  </p><p class="abstract"><strong>Results:</strong> Out of 50 cases operated, 84% patients of present study were in the age group of 18-30 years. The mean age was 25 years. The eldest patient in our study was 55 years old. 40 patients were males and 10 were females with male: female ratio of 4:1. Mean VHI score at preoperative, postoperative 1 week and postoperative 1 month were 23.2, 22 and 21.5 respectively. No statistical difference was obtained while comparing the mean VHI score at different time intervals. The scores between 0-30 are in the mild category i.e. minimal amount of handicap.</p><p><strong>Conclusions:</strong> According to our experience a widened nasal cavity has no effect on voice quality and procedures about nasal obstruction like septoplasty can be performed safely. However, professional voice users, in particular, should be informed about the possible minor postoperative changes, before the septoplasty procedure. </p>


Author(s):  
Kritika Agrawal ◽  
Shubhangi Mande ◽  
Lakshmi Rachakonda

Worldwide 20-30% of labour cases are induced. We conducted an analysis to evaluate the success of labour induction for indicated preterm birth A prospective observational study was conducted among 50 patients admitted in the Department of OBGY, MGM Medical College and Hospital, Aurangabad from 1st March 2019 to 31st March 2020. There was a total of 50 deliveries during this period. The preterm induction majorly includes 20-34 years as this is the commonest reproductive age group seen in our hospital. More number of Hindus underwent induction. Multigravida requires induction more as compared to primigravida. More number of patients were induced between 32-36 weeks, reason being PPROM, severe preeclampsia, IUD and severe FGR. Vaginal delivery is more likely irrespective of bishop score. Induction of labour remains relevant obstetrics procedure and its outcome will depend on proper choice of patients and close intrapartum monitoring


2020 ◽  
pp. 1-3
Author(s):  
Sandhya Bordia ◽  
Praveen Kumar Jain*

OBJECTIVE: The purpose of this prospective study is to study the spectrum of pediatric solid malignancies at our institution. METHOD: This study is under taken to evaluate the incidence and morphological features of solid malignant paediatric tumors in eighteen years and below. The material for present study is obtained from FNAC in cytology and biopsy specimen in histology department of RNT Medical college, Udaipur. RESULT: A total number 60 cases of malignant solid pediatric tumors of age group 0-18 years were diagnosed in Department of Pathology RNT Medical college Udaipur, during a period of two years. The number of malignancies diagnosed by Cytology accounted for 53.33% while Histopathology contributed 46.67% respectively. The male: Female ratio of childhood solid malignancies was 1.73:1. In malignant solid pediatric tumors CNS tumors were the commonest constituting 30% followed by Lymphoma 23.33%, Bone tumors 11.67% and neuroblastoma, retinoblastoma & spindle cell neoplasm 3.33% each. CONCLUSION: Our study concluded that solid malignant pediatric tumors contribute also a health problem in Udaipur region affecting all pediatric age group but more prevalent in the age group 6-10 years & 15-18 years.


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