scholarly journals Physiotherapy Rehabilitation in Subject with Scapular Osteochondroma: A Case Report

2021 ◽  
pp. 160-164
Author(s):  
Vaishnavi Thakare ◽  
Pratik Phansopkar ◽  
Neha Chitale
Keyword(s):  
Benign Tumor ◽  
Autosomal Dominant ◽  
Benign Tumour ◽  
Long Bone ◽  
X Rays ◽  
Case Presentation ◽  
Common Benign Tumor ◽  
Multiple Osteochondromas ◽  
Tumor Management

Introduction: The most prevalent benign tumour affecting the metaphysis of long bone is osteochondroma, a form of cartilaginous tumour. Solitary or multiple osteochondromas can prevail.Hereditary multiple exostosis (HME) or familial osteochondromatosis is the multiple variant, which is an autosomal dominant syndrome. Case Presentation: A 35-year old female with right-hand dominance was referred todepartment of physiotherapy. On palpation small nodular swelling of marble size was present in left axilla. X-rays findings showed increased scapular mass and ribs were compressed laterally. Discussion: The most widespread benign tumour is osteochondroma. In 3.0-6.4 percent of all instances, the scapula is implicated. The osteochondroma normally develops on the scapula's anterior aspect. The scapula osteochondroma induces pain and a grating sound when the scapula is moved. Mechanic irritation of muscle, tendon, or soft tissue, emergence of a pseudoaneurysm or bursa, fracture, or malignant transformation are all causes of symptoms. Conclusion: Osteochondroma is a common benign tumor. Management of osteochondroma is important to improve the quality of life. Physiotherapy plays an important role in managing Scapular osteochondroma.

scholarly journals GCT of knee treated with modular prosthesis-case presentation

2019 ◽  
Vol 2 (1) ◽  
pp. 18-22
Author(s):  
Alexandru Papuc ◽  
Ioan Mihai Japie ◽  
Traian Ciobanu ◽  
Octavian Nutiu ◽  
Dragos Radulescu ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Benign Tumor ◽  
Distal Femur ◽  
Proximal Tibia ◽  
Metastatic Potential ◽  
Left Knee ◽  
Case Presentation ◽  
Previous Medical History ◽  
Malignancy Potential

AbstractThe GCT is an aggressive benign tumor with metastatic potential, most often within the lungs in 2-3% of the patients. It makes about 5% of total bone tumors and about 15% of total benign bone tumors.The maximum incidence occurs between 30 and 40 years old, most frequently affecting the long bones epiphysis (distal femur, proximal tibia, and distal radius).We report the case of a 50-year-old female, with no previous medical history, admitted in the emergency department (ED) for significant pain and functional impairment of the left knee. Clinical examination and imaging tests established the diagnosis of distal femoral tumor.The patient underwent surgical segmental resection of the tumor within oncological limits and subsequent arthroplasty with cemented modular tumoral prosthesis was performed.Even if the GCT is a benign tumor, it has an aggressive behavior and malignancy potential with an important impact on quality of life. Due to localization, this type of tumor can quickly manifest clinically, which allows an early diagnosis and a less invasive surgical technique.

scholarly journals Impact of Balance Training and Co-ordination Exercises in Post-Operative Left Cerebellopontine Angle Tumor: A Case Report

2021 ◽  
pp. 413-416
Author(s):  
Aditi Akhuj ◽  
Snehal Samal ◽  
Rakesh Krishna Kovela ◽  
Ragini Dagal ◽  
Rebecca Thimoty
Keyword(s):  
Case Report ◽  
Acoustic Neuroma ◽  
Cerebellopontine Angle ◽  
Balance Training ◽  
Case Presentation ◽  
Cerebellopontine Angle Tumor ◽  
Acoustic Neuromas ◽  
Tumor Management ◽  
Mild Impairment

Introduction: Acoustic neuromas are most common tumors of CP angle, accounting more than 90% of all such tumors. Meningioma, primary cholesteratoma and facial nerve schwanoma are the different type of tumors. Acoustic neuroma is a benign tumor situates in CP angle which has a fibrous growth and originates from the division of vestibulochochlear nerve. Aim: Impact of Balance Training and Co-ordination Exercises in Post-Operative Left Cerebellopontine Angle Tumor Case Presentation: A 40 year old male with right hand dominance was referred to physiotherapy department. On examination he presented mild impairment in balance and co-ordination, assisted walking. Discussion: This case report is an important to the published literature on rehabilitation of a patient witha CPA tumor, as it presents the sequential management in the patients post CPA tumor. Conclusion: Acoustic neuroma is most common CPA tumor. Management of CPA tumor is important to improve quality of life. As per the reference articles and the exercises planned can progressively improve balance and co-ordination of patients.

scholarly journals Atrial myxoma with renal colic

2021 ◽  
Author(s):  
Yang Guo ◽  
Min Cao ◽  
Xiaobo Huang ◽  
Lingai Pan
Keyword(s):  
Renal Artery ◽  
Renal Colic ◽  
Benign Tumor ◽  
Cardiac Myxoma ◽  
Renal Infarction ◽  
Artery Embolization ◽  
Case Presentation ◽  
Common Benign Tumor ◽  
Renal Artery Embolization ◽  
The Right

Abstract Backgroundcardiac myxoma is a common benign tumor of the heart. It can have any presentation such as mitral stenosis, embolization. The best treatment is surgical resection.Case presentationA 30-year-old man presented with 2-days of right renal colic and chest tightness, dyspnea. He was diagnosed as renal infarction through ultrasound in another hospital and received some analgesic drugs. But the symptoms didn’t resolved and he came to our ICU(Intensive Care Medicine). We performed the ultrasonography and found a mass in the right atrium computed tomography angiography cofirmed it, and it was cross-valve growth, irregular shape, and slight enhancement of the enhanced edge, consider myxoma. Multiple non-reinforced areas were seen in the right renal cortex and medulla, right renal artery embolization, right renal infarction might be considered. The patient was taken to the operating room for emergent myxoma resection, renal artery thrombectomy.ConclusionMyxomas should be in differential diagnosis in patient present with thromboembolism. Early diagnosis and surgical are crucial treatment in deal with myxoma.

scholarly journals Application of Multimodal and Molecular Imaging Techniques in the Detection of Choroidal Melanomas

2021 ◽  
Vol 10 ◽  
Author(s):  
Xuying Li ◽  
Lixiang Wang ◽  
Li Zhang ◽  
Fei Tang ◽  
Xin Wei
Keyword(s):  
Molecular Imaging ◽  
Benign Tumor ◽  
Malignant Tumors ◽  
Imaging Techniques ◽  
Choroidal Melanoma ◽  
Common Benign Tumor ◽  
Choroidal Melanomas ◽  
Choroidal Nevus ◽  
Choroidal Nevi

Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset of such tumors is insidious, such that affected patients often have no pain or obvious discomfort during early stages. Notably, enucleation is required for patients with a severe choroidal melanoma, which can seriously impact their quality of life. Moreover, choroidal melanomas metastasize early, often to the liver; this eventually causes affected patients to die of liver failure. Therefore, early diagnosis of choroidal melanomas is extremely important. Unfortunately, an early choroidal melanoma is easily confused with a choroidal nevus, which is the most common benign tumor of the eye and does not often require surgical treatment. This review discusses recent advances in the use of multimodal and molecular imaging to identify choroidal melanomas and choroidal nevi, detect early metastasis, and diagnose patients with choroidal melanomas.

scholarly journals Fibrodysplasia ossificans progressiva (stone man syndrome): a case report

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Zakir Ali Shah ◽  
Sascha Rausch ◽  
Uzma Arif ◽  
Bilal El Yafawi
Keyword(s):  
Early Diagnosis ◽  
Heterotopic Ossification ◽  
Autosomal Dominant ◽  
Surgical Intervention ◽  
Surgical Excision ◽  
Fibrodysplasia Ossificans Progressiva ◽  
Test Results ◽  
Autosomal Dominant Disorder ◽  
Case Presentation

Abstract Background Fibrodysplasia ossificans progressiva is an ultrarare autosomal dominant disorder and disabling syndrome characterized by postnatal progressive heterotopic ossification of the connective tissue and congenital malformation of the big toes. Fibrodysplasia ossificans progressiva has worldwide prevalence of about 1 in 2 million births. Nearly 90% of patients with fibrodysplasia ossificans progressiva are misdiagnosed and mismanaged and thus undergo unnecessarily interventions. So far, the number of reported existing cases worldwide is about 700. Clinical examination, radiological evaluation, and genetic analysis for mutation of the ACVR1 gene are considered confirmatory tools for early diagnosis of the disease. Association of fibrodysplasia ossificans progressiva with heterotopic ossification is well documented; however, postsurgical exaggerated response has never been reported previously, to the best of our knowledge. Case presentation We report a case of a 10-year-old Pakistani boy brought by his parents to our institution. He had clinical and radiological features of fibrodysplasia ossificans progressive and presented with multiple painful lumps on his back due to hard masses and stiffness of his shoulders, neck, and left hip. He underwent surgical excision of left hip ossification followed by an exaggerated response in ossification with early disability. Radiological examination revealed widespread heterotopic ossification. All of his laboratory blood test results were normal. Conclusion Fibrodysplasia ossificans progressiva is a very rare and disabling disorder that, if misdiagnosed, can lead to unnecessary surgical intervention and disastrous results of early disability. We need to spread knowledge to physicians and patients’ family members about the disease, as well as its features for early diagnosis and how to prevent flare-up of the disease to promote better quality of life in these patients.

scholarly journals Inappropriate surgery in a patient with misdiagnosed Robert’s uterus

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Iori Kisu ◽  
Kanako Nakamura ◽  
Tetsuro Shiraishi ◽  
Tomoko Iijima ◽  
Moito Iijima ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Uterine Wall ◽  
Septate Uterus ◽  
Case Presentation ◽  
Surgical Interventions ◽  
Unicornuate Uterus ◽  
Uterine Malformation ◽  
Mullerian Anomaly ◽  
Future Pregnancy

Abstract Background Robert’s uterus is a rare Mullerian anomaly, which can be described as an asymmetric, septate uterus with a non-communicating hemicavity. Herein, we present the case of a misdiagnosed Robert’s uterus, resulting in an invasive and disadvantageous surgery. Case presentation A 16-year-old woman was referred to our department because of dysmenorrhea and suspicion of uterine malformation. We misdiagnosed Robert’s uterus as a unicornuate uterus with a non-communicating rudimentary horn and hematometra, and performed laparoscopic hemi-hysterectomy. Although the patient’s symptoms were relieved, our surgical procedure left the lateral uterine wall weak, making the patient’s uterus susceptible to uterine rupture in any future pregnancy. Conclusions Although the early diagnosis of Robert’s uterus is challenging, it is important in order to determine appropriate surgical interventions and management for maintaining the quality of life and ensuring safety in future pregnancies.

Efficacy and safety of denosumab treatment in a prepubertal patient with cherubism

2020 ◽  
Vol 33 (7) ◽  
pp. 963-966
Author(s):  
Haruka Kawamura ◽  
Satoshi Watanabe ◽  
Takashi I ◽  
Izumi Asahina ◽  
Hiroyuki Moriuchi ◽  
...  
Keyword(s):  
Autosomal Dominant ◽  
Therapeutic Potential ◽  
Giant Cells ◽  
Efficacy And Safety ◽  
Autosomal Dominant Disorder ◽  
Osteolytic Lesions ◽  
Case Presentation ◽  
Childhood Growth ◽  
Receptor Activator ◽  
Denosumab Treatment

AbstractBackgroundDenosumab is an inhibitor of receptor activator of nuclear factor kappa-B ligand, which strongly suppresses osteoclasts. Cherubism is a rare autosomal dominant disorder characterized by symmetrical swelling of the jaws, in which the bone is replaced by a fibrous granuloma containing osteoclast-like giant cells.Case presentationWe report the efficacy and safety of denosumab treatment in a prepubertal boy with progressive cherubism. The treatment consisting of eight subcutaneous denosumab injections (120 mg/dose) in 6 months not only suppressed the expansion of the osteolytic lesions but also dramatically ossified them. However, a transiently decreased growth rate and rebounded asymptomatic hypercalcemia were associated with the treatment.ConclusionsThe present case demonstrated the therapeutic potential of denosumab for treatment of cherubism, although adverse effects, especially those on childhood growth, remain obscure. Further studies are needed to establish a safe and effective protocol for denosumab treatment of children.

scholarly journals Tolvaptan in Pediatric Autosomal Dominant Polycystic Kidney Disease: From Here to Where?

2021 ◽  
pp. 1-7
Author(s):  
Fei Liu ◽  
Chunyue Feng ◽  
Huijun Shen ◽  
Huaidong Fu ◽  
Jianhua Mao
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Pediatric Patients ◽  
Autosomal Dominant ◽  
Life Assessment ◽  
Therapeutic Approaches ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney ◽  
Ongoing Phase

<b><i>Background:</i></b> Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder, accounting for approximately 5% of all ESRD cases worldwide. As a vasopressin receptor 2 antagonist, tolvaptan is the FDA-approved therapeutic agent for ADPKD, which is only made available to a limited number of adult patients; however, its efficacy in pediatric patients has not been reported widely. <b><i>Summary:</i></b> Tolvaptan was shown to delay ADPKD progression in the Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes (TEMPO) 3:4 study, Replicating Evidence of Preserved Renal Function: an Investigation of Tolvaptan Safety and Efficacy in ADPKD (REPRISE) trial, and other clinical studies. In addition to its effects on aquaretic adverse events and alanine aminotransferase elevation, the effect of tolvaptan on ADPKD is clear, sustained, and cumulative. While ADPKD is a progressive disease, the early intervention has been shown to be important and beneficial in hypotheses as well as in trials. The use of tolvaptan in pediatric ADPKD involves the following challenges: patient assessment, quality of life assessment, cost-effectiveness, safety, and tolerability. The ongoing, phase 3b, 2-part study (ClinicalTrials.gov identifier: NCT02964273) on the evaluation of tolvaptan in pediatric ADPKD (patients aged 12–17 years) may help obtain some insights. <b><i>Key Messages:</i></b> This review focuses on the rationality of tolvaptan use in pediatric patients with ADPKD, the associated challenges, and the suggested therapeutic approaches.

Autosomal Dominant Frontotemporal Lobar Degeneration in a Filipino Family with Progranulin Mutation

2021 ◽  
pp. 1-8
Author(s):  
Jacqueline Dominguez ◽  
Arlene Ng ◽  
Jeryl Yu ◽  
Anne Cristine Guevarra ◽  
Maria Luisa Daroy ◽  
...  
Keyword(s):  
Frontotemporal Lobar Degeneration ◽  
White Matter Hyperintensities ◽  
Autosomal Dominant ◽  
The Philippines ◽  
Vascular Risk ◽  
Case Presentation ◽  
Nonfluent Aphasia ◽  
Protein Tau ◽  
Review Reports ◽  
Progressive Nonfluent Aphasia

<b><i>Background:</i></b> Compared to Western populations, familial frontotemporal lobar degeneration (FTLD) is rare among Asians. Progranulin (GRN) gene mutation, which is a major cause of FTLD, is likewise rare. We present a family with FTLD from the Philippines with an autosomal dominant pattern of inheritance and GRN mutation and briefly review reports of GRN mutations in Asia. <b><i>Case Presentation:</i></b> The proband is 66 years old with progressive nonfluent aphasia (PNFA)-corticobasal syndrome . We assessed 3 generations of her pedigree and found 11 affected relatives with heterogenous phenotypes, usually behavioral variant frontotemporal dementia (FTD) and PNFA. Neuroimaging showed atrophy and hypometabolism consistent with FTD syndromes. White matter hyperintensities were seen in affected members even in the absence of vascular risk factors. A GRN mutation R110X was found in 6 members, 3 with symptoms and 3 were asymptomatic. Plasma GRN was low (&#x3c;112 ng/mL) in all mutation carriers. No mutations were found in microtubule-associated protein tau, APP, PSEN1, and PSEN2 genes, and all were APOE3. <b><i>Conclusion:</i></b> This is the first Filipino family with autosomal dominant FTD documented with GRN mutation. Identifying families and cohorts would contribute to therapeutic developments in an area with FTD-GRN.

scholarly journals Immediate Care of Open Extremity Fractures: Where Can We Improve?

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
R. Walton ◽  
J. Manara ◽  
S. E. Elamin ◽  
I. Braithwaite ◽  
E. Wood
Keyword(s):  
Acute Care ◽  
Bone Fractures ◽  
Working Hours ◽  
District General Hospital ◽  
Open Fractures ◽  
Care Staff ◽  
Long Bone ◽  
Initial Management ◽  
Clinical Consequences

Clear guidelines are set by the British Orthopaedic Association (BOA) and British Association of Plastic, Reconstructive and Aesthetic Surgeons (BAPRAS) on the preoperative management of open fractures. This as well as the clinical consequences of poor management of open fractures means the patient workup for surgery is important as well as the timing of surgery. Experience suggests few patients are managed 100% as per the guidelines and we look to test this hypothesis. A retrospective analysis was undertaken of all open long bone fractures (total 133), excluding hand injuries, which presented to a district general hospital over a 5-year period. The implementation of 7 defined key tasks for initial management was recorded. 101 cases were eligible, with the majority of cases (71.4%) having initial orthopaedic assessment outside normal working hours. The mean number of tasks completed was 3.23/7. Assessment out of hours was associated with less tasks being implemented but doctor seniority and the presence of polytrauma made no difference to the quality of acute care. Staff involved in the acute care of open fractures require targeted education to improve the delivery of initial preoperative care. We recommend that other centres assess their performance against this data.

Sign in / Sign up

Export Citation Format

Share Document