scholarly journals Evaluation of Comparative Efficacy of Jyotishmati (Celastrus paniculatus Wild) and Yastimadhu (Glycyrrhiza glabra Linn) in Enhancing IQ and Memory of Different Prakriti School Going Children-A Study Protocol of Double Blind Randomized Clinical Trial

2021 ◽  
pp. 236-244
Author(s):  
Ibamedabha Japang ◽  
Renu Rathi ◽  
Bharat Rathi ◽  
Jitesh Verma ◽  
V. B. Pandey
Keyword(s):  
School Performance ◽  
Randomized Trials ◽  
School Age Children ◽  
Research Centre ◽  
School Age ◽  
Comparative Efficacy ◽  
Double Blind ◽  
College Hospital ◽  
Memory Assessment ◽  
Parallel Group

Background: Education plays a major role in life, whereas lack of intelligence, learning, and memory will lead to failure in school performance and school dropout. Medhya drugs are used frequently to enhance the memory and IQ in children. Jyotishmati and Yashtimadhu are medhya (IQ-enhancing & memory-booster) drugs, described in numerous classical texts of Ayurveda. However, comparative efficacy and randomized trials on various prakriti types have not been studied. Thus, to assess the comparative efficacy of Jyotishmati in enhancing IQ and memory in relation to Yastimadhu as standard control, this research has been planned. Objective: To evaluate the efficacy of Jyotishmati on IQ and memory, and compare the efficacy with that of Yastimadhu in children with different prakriti types. Methodology: It will be conducted on healthy school-age children of 8-13 years, recruited from CBSE schools near Mahatma Gandhi Ayurved College, Hospital and Research Centre, Salod, Wardha. The study will be a randomized, standard-controlled, double-blind, parallel group clinical study. All participants will be randomly divided into two groups, each of 30 individuals; each group is subdivided into three subgroups of 10 individuals each. One group will be given Jyotishmati while the other will be given Yastimadhu, both in granule form. IQ assessment will be done by using the Draw a Man test and the PGI memory scale for memory assessment. Expected Results: This study will validate the efficacy of Jyotishmati and Yastimadhuin enhancing IQ and memory, and it will give detailed information about their efficacy in different Prakriti dominantchildren. Conclusion: This study will provide unique information to increase awareness of the administration of Medhya drugs according to Prakriti, as well as knowledge about which drug is best for improving either IQ or memory, or both.

scholarly journals Evaluation of effectiveness of rupatadine and olopatadine in patients of allergic rhinitis at Indore: a randomized control trial

2017 ◽  
Vol 6 (7) ◽  
pp. 1753
Author(s):  
Jay Shah ◽  
Poonam Patel
Keyword(s):  
Allergic Rhinitis ◽  
Cost Effective ◽  
Nasal Symptom ◽  
Research Centre ◽  
Differential Count ◽  
Double Blind ◽  
College Hospital ◽  
Treatment Groups ◽  
Medical College ◽  
Parallel Group

Background: Allergic rhinitis (AR) is one of the most prevalent atopic disorders that affect productivity and quality of life. Although individually olopatadine and rupatadine are efficacious in AR, data on the head to head study of these drugs in Indian population are scanty, so present study was undertaken with an aim to compare the efficacy, safety, and cost effectiveness of rupatadine and olopatadine in patients’ of allergic rhinitis.Methods: A prospective, randomized, double blind, parallel group, comparative 2 weeks clinical study conducted in eighty patients of AR in the Department of Pharmacology, Index Medical College Hospital and Research Centre, Indore. Following inclusion and exclusion criteria, 67 patients were recruited and randomized to two treatment groups and received the respective drugs for 2 weeks. At follow-up, parameters assessed were total nasal symptom score (TNSS), change in total and differential count of eosinophil.Results: In olopatadine group, there was a significantly higher reduction in TNSS (P < 0.05) than that of rupatadine. Both the drugs significantly reduced the absolute eosinophil count, but olopatadine (P <0.001) was found to be superior. The incidence of adverse effects was found to be less in olopatadine group when compared with rupatadine group.Conclusions: Both rupatadine and olopatadine provide effective relief of the symptoms of AR. However, clinical benefit occurs significantly more with olopatadine. However, rupatadine was more cost‑effective than olopatadine in treating the patients of AR in term of effectiveness.

Effects of Consumption of Probiotic Powder Containing Lactobacillus Plantarum Dad-13 on Fecal Bacterial Population in School-Age Children in Indonesia

2019 ◽  
Vol 14 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Banin Maghfirotin Marta ◽  
Utami Tyas ◽  
Cahyanto Muhammad Nur ◽  
Widada Jaka ◽  
Rahayu Endang Sutriswati
Keyword(s):  
Placebo Group ◽  
Gut Microbiota ◽  
Lactobacillus Plantarum ◽  
Coliform Bacteria ◽  
School Age Children ◽  
Controlled Study ◽  
School Age ◽  
Double Blind ◽  
Probiotic Group ◽  
E Coli

Consumption of probiotics is known to influence the gut microbiota. The aim of this study was to assess the effect of probiotic powder containing Lactobacillus plantarum Dad-13 on bacterial composition in the gut by examining fecal samples of school-age children in Yogyakarta, Indonesia. This is a randomized, double-blind, placebo-controlled study. A total of 40 healthy subjects were recruited for this study and were divided into two groups: placebo group and probiotic group. The placebo group consumed skim milk and the probiotic group consumed probiotic powder containing L. plantarum Dad-13 (2 × 109 CFU/g) for 65 days. The results showed that placebo intake had no significant effect on gut microbiota; however, probiotic caused a significant increase in L. plantarum and Lactobacillus population, while decreasing the population of E. coli and non-E. coli coliform bacteria by 55% and 75%, respectively and Bifidobacteria count did not change significantly. The study concluded that consumption of probiotic powder L. plantarum Dad-13 could increase propionic acid thereby decreasing the gut pH which has an effect on the microbial population.

scholarly journals Assessment of nutritional status of primary school children in urban field practice area, Vijayapura

2018 ◽  
Vol 5 (2) ◽  
pp. 779
Author(s):  
Sandeep G. Yankanchi ◽  
Praveen Ganganahalli ◽  
Rekha Udgiri ◽  
Shailaja S. Patil
Keyword(s):  
Nutritional Status ◽  
Primary School ◽  
School Children ◽  
Primary School Children ◽  
School Age Children ◽  
Research Centre ◽  
Anthropometric Measurement ◽  
College Hospital ◽  
Cross Sectional ◽  
Field Practice

Background: Children are nature`s gift and fountain of life. They are future citizens and their health is nation`s wealth. There is a meaningful saying that ‘nation marches on tiny feet of young children and no nation without due love and attention paid to its children will lead to social and economic development. By promoting their good health we will be strengthening the development of the family, nation and world. As per National Family Health Survey IV, 38.4% children in India are stunted, 21% wasted and nearly 35.7% are under weight. Karnataka has a prevalence of stunting (36.2%), wasting (26%) and underweight (35.2%). The objective was assessment of nutritional status of primary school children of urban field practice area. Methods: A cross-sectional study was conducted in Maddy primary school located in Dorgalli, Urban field practical area, Chandabowdi, dept. of Community Medicine, Shri B.M. Patil medical college hospital and Research centre, Vijayapura. All children were assessed for nutritional status by taking anthropometric measurement like Height, Weight and also for nutritional deficiency disorders by detailed general physical examination. Analysis was done using frequency distribution, calculation of height for age, weight for age, weight for height and classified malnutrition according to IAP and Water low’s classification. Results: Around 57% of primary school children were found to be having less weight and/or height with respect to their age and sex. Conclusions: The present finding is going to affect the growth and development primary school age children who are more vulnerable for vicious cycle of malnutrition and infection. Regular monitoring of growth of primary school children and health education session for the mothers is going to be effective in prevention of malnutrition among the children. 

scholarly journals Epidemiological characteristics of child injury in a tertiary paediatric surgical centre in Bangladesh

2020 ◽  
Vol 6 (3) ◽  
pp. 577-586
Author(s):  
Tanvir Kabir Chowdhury ◽  
Ayesha Sadia ◽  
Rumana Khan ◽  
Abida Farjana ◽  
Efat Sharmin ◽  
...  
Keyword(s):  
Seasonal Variations ◽  
Road Traffic ◽  
School Age Children ◽  
Paediatric Surgery ◽  
School Age ◽  
Mechanism Of Injury ◽  
Child Injury ◽  
College Hospital ◽  
Female Ratio ◽  
Epidemiological Characteristics

While high income countries (HICs) have reduced the mortality from child injury, it is increasing in the low- and middle-income countries (LMICs). However, injury registry and reporting are inconsistent and not well developed in the LMICs. This study aims at describing the epidemiology of child injury in a tertiary paediatric surgical centre in Bangladesh. We retrospectively analysed all patients of injury between 0 and 12 years of age admitted in the Department of Paediatric Surgery, Chattogram Medical College Hospital during January 2017 to June 2020. Analysis was done for the hospital prevalence, age and sex distribution, seasonal variations, mechanism of injury, site of involvement, and mortality from injury. There were a total of 538 patients and male to female ratio was 2.01:1. Hospital prevalence was 6.71%. Mean age was 6.60 ± 3.32 years. School age children were affected more (51.7%); and “6-10 years” age group had the highest number injuries (251 patients, 46.65%). The most common mechanisms of injuries were road-traffic accident (RTA, 35.32%), followed by fall (26.39%) and „stab or cut injury‟ (20.63%). Males experienced more abdominal injuries and females had more perineal injuries (P=0.00). RTA was the commonest mechanism in males (37.05%) and falls were the commonest mechanism in females (32.96%). „Stab or cut injury‟ was the commonest mechanism in infants and toddlers, and RTA was commonest among pre-school and school age children. There were no significant seasonal variations (P=0.09). There were 5.76% intentional injuries. Mortality was 2.60% and major causes of mortality were RTA and animal assaults. Injuries were more prevalent during the mid-childhood with an overall increasing trend with age. Mechanism of injury and site of involvement were different among different age groups and between sexes. Asian J. Med. Biol. Res. September 2020, 6(3): 577-586

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