scholarly journals Uma perspectiva mundial do carcinoma de células escamosas de pele

2009 ◽  
Vol 8 (1) ◽  
pp. 91
Author(s):  
Sarah Regina de Paula Sousa ◽  
Júlio Cesar Andriotti Borges ◽  
Pedro Aquino Ferreira Paulo ◽  
Raimundo F. de Araújo-Júnior
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cancer Epidemiology ◽  
Squamous Cells ◽  
Non Melanoma Skin Cancer ◽  
Carcinoma Squamous Cell ◽  
Penile Squamous Cell Carcinoma ◽  
Melanoma Skin

O Carcinoma de Células Escamosas (SCC) é a segunda neoplasia maligna cutânea mais freqüente, causada primordialmente pela exposição crônica e excessiva à radiação ultravioleta. O objetivo deste trabalho é discutir o perfil epidemiológico global do SCC através de uma revisão sistemática. Foi realizada uma busca na base de dados PUBMED com a utilização dos termos: squamous cells skin cancer, epidemiology squamous cells skin cancer, penile squamous cell carcinoma, squamous cell carcinoma of the penis, vulva SCC epidemiology e depletion of ozone layer. Outra busca foi realizada na base de dados SCIENCE DIRECT, com os termos: epidemiology of non-melanoma skin cancer, epidemiology of squamous cells carcinoma, squamous cells carcinoma, skin cancer, e, por fim, o termo UV radiation. No total, 19 artigos foram selecionados, sendo considerados aqueles publicados a partir de 2000. A revisão permitiu verificar que estudos em países de todos os continentes mostram um número crescente de casos, o que configura um grave problema de saúde pública mundial.

Variation in Skin Cancer Pattern in the Southwestern Region of Pakistan

2021 ◽  
Vol 15 (12) ◽  
pp. 3402-3404
Author(s):  
Hina , Manzoor ◽  
Najeeb Ahmad ◽  
Zafar H Tanveer ◽  
Khush Naseed Ahmed ◽  
Munir , Ahmed ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Published Data ◽  
Non Melanoma Skin Cancer ◽  
Broad Term ◽  
The Difference ◽  
Field Workers ◽  
Melanoma Skin

Background: Skin cancer is a broad term that refers to a variety of different types of cancer. It is usually recognized as non-melanoma and melanoma skin cancer. In many parts of the world, the prevalence is high, with significant ecological and ethical variation. Objectives: Objective was to determine demographic and histological features of skin cancer in Southwest region of Pakistan. Methodology: This retrospective study was carried out on skin cancer 1169 cases of Centre for Nuclear Medicine and Radiotherapy (CENAR) in Quetta. The data from January 2000 to December 2009 (10Years) was retrieved from record. The aim was to determine the importance of skin cancer in this area, its gender wise distribution and its pathological types. Results: Record of total 9308 cancer patients was retrieved from patients presenting to CENAR Quetta. From 9308 case, 1169(12.5%) patients were of skin cancer which was second most prevalent category of cancer in this area. Prevalence was higher in males with 713(61%) cases as compared to females. Pathologically with 634(54%) cases, the most prevalent category was Squamous cell carcinoma (SCC). Conclusion: Skin cancer is wide-spread type of cancer in patients of south-west region of Pakistan. The findings of this study are not aligned with published data. The difference is because of high altitude of the study area, dry climate and long skin exposure particularly in low socio-economic field workers. Keywords: Skin cancer, gender, Melanoma skin cancer (MSC), Squamous cell carcinoma (SCC), Non-melanoma skin cancer (NMSC), Basal cell carcinoma (BCC),

scholarly journals Patient-Derived Human Basal and Cutaneous Squamous Cell Carcinoma Tissues Display Apoptosis and Immunomodulation Following Gas Plasma Exposure with a Certified Argon Jet

2021 ◽  
Vol 22 (21) ◽  
pp. 11446
Author(s):  
Fariba Saadati ◽  
Juliane Moritz ◽  
Julia Berner ◽  
Eric Freund ◽  
Lea Miebach ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Plasma Treatment ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Ex Vivo ◽  
Plasma Exposure ◽  
Gas Plasma ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Reactive oxygen species (ROS) have been subject of increasing interest in the pathophysiology and therapy of cancers in recent years. In skin cancer, ROS are involved in UV-induced tumorigenesis and its targeted treatment via, e.g., photodynamic therapy. Another recent technology for topical ROS generation is cold physical plasma, a partially ionized gas expelling dozens of reactive species onto its treatment target. Gas plasma technology is accredited for its wound-healing abilities in Europe, and current clinical evidence suggests that it may have beneficial effects against actinic keratosis. Since the concept of hormesis dictates that low ROS levels perform signaling functions, while high ROS levels cause damage, we investigated herein the antitumor activity of gas plasma in non-melanoma skin cancer. In vitro, gas plasma exposure diminished the metabolic activity, preferentially in squamous cell carcinoma cell (SCC) lines compared to non-malignant HaCaT cells. In patient-derived basal cell carcinoma (BCC) and SCC samples treated with gas plasma ex vivo, increased apoptosis was found in both cancer types. Moreover, the immunomodulatory actions of gas plasma treatment were found affecting, e.g., the expression of CD86 and the number of regulatory T-cells. The supernatants of these ex vivo cultured tumors were quantitatively screened for cytokines, chemokines, and growth factors, identifying CCL5 and GM-CSF, molecules associated with skin cancer metastasis, to be markedly decreased. These findings suggest gas plasma treatment to be an interesting future technology for non-melanoma skin cancer topical therapy.

Non-melanoma Skin Cancer in Canada Chapter 5: Management of Squamous Cell Carcinoma

2015 ◽  
Vol 19 (3) ◽  
pp. 249-259 ◽  
Author(s):  
Mariusz Sapijaszko ◽  
David Zloty ◽  
Marc Bourcier ◽  
Yves Poulin ◽  
Peter Janiszewski ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Surgical Excision ◽  
Non Melanoma Skin Cancer ◽  
Canadian Health ◽  
Canadian Health Care ◽  
Margin Control ◽  
Melanoma Skin

Background Squamous cell carcinoma (SCC) is the second-most common form of non-melanoma skin cancer (NMSC). Objective To provide guidance to Canadian health care practitioners regarding management of SCCs. Methods Literature searches and development of graded recommendations were carried out as discussed in the accompanying introduction (chapter 1 of the NMSC guidelines). Results SCCs are sometimes confined to the epidermis, but they can also invade nearby tissues and, in some cases, metastasize to neighbouring lymph nodes or other organs. This chapter discusses the natural history, staging, prognosis, and management of SCC—a tumour type that is less common but typically more aggressive than BCC. For this reason, margin control is strongly preferred in treating SCCs. Conclusions Although approaches such as cryosurgery and radiation therapy may be considered for some patients, surgical excision—sometimes coupled with radiation—remains the cornerstone of SCC management. Patients with high-risk SCC may also be considered for referral to an appropriate multidisciplinary clinic.

Trends in Non-Melanoma Skin Cancer (Basal Cell Carcinoma and Squamous Cell Carcinoma) in Canada

2015 ◽  
Vol 20 (2) ◽  
pp. 166-175 ◽  
Author(s):  
Mariam Abbas ◽  
Sunil Kalia
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Age Cohorts ◽  
Non Melanoma Skin Cancer ◽  
Younger Age ◽  
Melanoma Skin

Background: Despite its increased incidence and status as the most prevalent cancer in Canada, there is a paucity of epidemiological data on non-melanoma skin cancer (NMSC). Objective: To assess trends of keratinocyte carcinomas (KC) in Canada over 5 decades. Methods: Articles published from 1960 to 2015 on NMSC in Canada were identified through MEDLINE. Six articles met our search criteria. Results: Overall, KC has increased. However, the rate of increase in the past decade has slowed down and decreased in younger age cohorts. Men had higher incidences of KC. In both sexes, the basal cell carcinoma and squamous cell carcinoma ratio was ≥2.5:1. Keratinocyte carcinomas were most commonly located on the head and neck, and increasing rates are occurring on the trunk. Limitations: The methods of registering skin cancer cases vary among different provinces. Conclusion: Keratinocyte carcinomas incidence is overall increasing; however, there may be evidence that the incidence is leveling off and decreasing in younger age cohorts.

Mohs Surgery versus Standard Local Excision for Basal Cell Carcinoma, Squamous Cell Carcinoma, and Melanoma Skin Cancer

2020 ◽  
Vol 36 (02) ◽  
pp. 133-140
Author(s):  
Timothy M. Johnson ◽  
Noah R. Smith
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Mohs Surgery ◽  
Skin Cancers ◽  
The Face ◽  
Carcinoma Squamous Cell ◽  
Melanoma Skin

AbstractBasal cell carcinoma, squamous cell carcinoma, and melanoma represent the three most common skin cancers that occur on the face. The most common surgical treatments for facial skin cancers are Mohs surgery and standard local excision. The effective utilization of either of these techniques is based on tumor and patient risk stratification incorporating known risk factors for occult invasion and local recurrence, combined with patient comorbidities, expectations, and desires. Best available evidence highlights multiple and consistent risk factors for each specific skin cancer type, and dictate local control rates reported in the literature. Recognizing gaps in the literature, we compare and review surgical treatment guidelines and data for standard local excision versus Mohs surgery for cutaneous nonmelanoma and melanoma skin cancer. This article serves as a resource for optimal therapeutic decision making for surgical management of skin cancer on the face.

Non-melanoma skin cancer and premalignant conditions

2021 ◽  
pp. 69-78
Author(s):  
Barbara Jemec ◽  
Gregor B.E. Jemec
Keyword(s):  
Squamous Cell Carcinoma ◽  
Surgical Treatment ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Merkel Cell ◽  
Non Melanoma Skin Cancer ◽  
Skin Cancers ◽  
Carcinoma Squamous Cell ◽  
Non Surgical Treatment ◽  
Melanoma Skin

This chapter describes the diagnosis, non-surgical treatment, and surgical treatment of non-melanoma skin cancers, such as basal cell carcinoma, squamous cell carcinoma, Merkel cell carcinoma, and others.

A PENILE SQUAMOUS CELL CARCINOMA WITH SYSTEMIC METASTASIS IN A THOROUGHBRED HORSE

2017 ◽  
Vol 43 (03) ◽  
pp. 195-199 ◽  
Author(s):  
Wen-Ta Li ◽  
Chun-Hao Chang ◽  
Chian-Ren Jeng ◽  
Victor Fei Pang ◽  
Fun-In Wang
Keyword(s):  
Polymerase Chain Reaction ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Chain Reaction ◽  
Thoroughbred Horse ◽  
Squamous Cells ◽  
Systemic Metastasis ◽  
Polymerase Chain ◽  
Penile Squamous Cell Carcinoma

A 22-year-old gelding Thoroughbred horse had been in poor physical condition with a prolapsed penis. On necropsy, numerous white nodules/plaques were found on the lungs, omentum, and multiple lymph nodes, as well as several ulcerations and cauliflower-like growths throughout the glans penis to the internal fold. Histologically, the white nodules/plaques were composed of similar neoplastic squamous cells, which were immunostained positive for cytokeratin (CK), CK 5/6, and P63. The cauliflower-like growths were diagnosed as squamous papilloma, inverted papilloma, and penile squamous cell carcinoma (PSCC). It is speculated that the lung metastasis and peritoneal carcinomatosis in this case are derived from the PSCC. The lesion tissues from the penis and omentum were characterized negative, by polymerase chain reaction, for Equus caballus papillomavirus 2 (EcPV2). This finding suggests that the penile lesions may have been irrelevant to the EcPV2, further implying that multiple pathogeneses exist for the development of an equine PSCC.

scholarly journals Penile Squamous Cell Carcinoma in A Boerboel Dog in Ibadan, Nigeria – A Case Report

2021 ◽  
Vol 3 (1) ◽  
pp. 107-111
Author(s):  
O.G Ohore
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Squamous Cells ◽  
First Case ◽  
Appropriate Treatment ◽  
High Cellularity ◽  
Cytological Evaluation ◽  
Penile Squamous Cell Carcinoma ◽  
Ibadan Nigeria

This report describes the first case of penile squamous cell carcinoma (SCC) in a Boerboel from our environment while emphasizing the importance of cytology as a quick and reliable diagnostic tool in clinical setting. The dog presented with a complaint of bloody urination had a noticeable growth on the penis. There was high cellularity of neoplastic squamous cells admixed numerous neutrophils and keratin within the background upon cytological evaluation. Therefore, cytological evaluation can become a ready tool for the diagnosis of SCC for appropriate treatment.

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