Synthesis, Hydrophilicity and Micellization of Coil–Brush Polystyrene-b-(polyglycidol-g-polyglycidol) Copolymer—Comparison with Linear Polystyrene-b-Polyglycidol

In this paper, an original method of synthesis of coil–brush amphiphilic polystyrene-b-(polyglycidol-g-polyglycidol) (PS-b-(PGL-g-PGL)) block copolymers was developed. The hypothesis that their hydrophilicity and micellization can be controlled by polyglycidol blocks architecture was verified. The research enabled comparison of behavior in water of PS-b-PGL copolymers and block–brush copolymers PS-b-(PGL-g-PGL) with similar composition. The coil–brush copolymers were composed of PS-b-PGL linear core with average DPn of polystyrene 29 and 13 of polyglycidol blocks. The DPn of polyglycidol side blocks of coil–b–brush copolymers were 2, 7, and 11, respectively. The copolymers were characterized by 1H and 13C NMR, GPC, and FTIR methods. The hydrophilicity of films from the linear and coil–brush copolymers was determined by water contact angle measurements in static conditions. The behavior of coil–brush copolymers in water and their critical micellization concentration (CMC) were determined by UV-VIS using 1,6-diphenylhexa-1,3,5-trien (DPH) as marker and by DLS. The CMC values for brush copolymers were much higher than for linear species with similar PGL content. The results of the copolymer film wettability and the copolymer self-assembly studies were related to fraction of hydrophilic polyglycidol. The CMC for both types of polymers increased exponentially with increasing content of polyglycidol.

Vilyui-Markha interfluve of Yakutia: a region prospective for Cu-Ni-PGM mineralization

Materials are discussed on geologically similar structure of Norilsk ore district (NOD) and Vilyui-Markha interstream area (VMIA), which implies the latter prospects for Cu-Ni-PGM mineralization. Data is provided on Cu-Ni-Co-Zn mineral occurrences within Ygyattinsky diamondiferous region centered on VMIA. Geological similarities of NOD and VMIA are summarized below. Both regions are located in Mesozoic tectonomagmatic activation domain at the edge of large troughs: NOD is localized in the Siberian platform foredeep, and VMIA lies at Vilyui syneclise margin. NOD deposits are hosted by centroclines of large brachysynclines at slopes of Pyasinskoye dome. Within VMIA, prospects are located at Syuldyukarskoye dome slopes in margibal parts of large troughs. NOD and VMIA comprise Paleozoic marl-carbonate strata overlain by carbonaceous Carboniferous-Permian overburden, which could be assimilated by basaltic magma in Mesozoic contributing to its ore differentiation. Norilsk-Kharaelakh ore-bearing intrusion in VMIA appears to be similar to Kholomolokh sulfide-rich intrusion with its inferred extensive ore-bearing sills. They have similar composition and structure including presence of pegmatites. Ore-controlling Norilsk-Kharaelakh fault is believed to be simi- lar to Khatyryk-Kholomolokh fault, which was traced for 24 km by drilling and is one of sutures within deep-seated kimberlite-controlling Vilyui-Markha zone. This fault’s impact zone host concentrated geochemical anomalies and Cu-Ni-Co-Zn-Pt-Au-Ag Khomustakh occurrence. Based on this, Norilsk-type Cu-Ni prospects ranked as a potential ore cluster and three ore fields were identified

Human milk: processing and conservation – a review

Human milk has a balance of nutrients and bioactive compounds, and it must be the exclusive food source during the first six months of the infant's life. In cases where the woman is unable to breastfeed, due to hypogalactia or pre-existing disease, the use of donated human milk, available in human milk banks, is recommended. Currently, in the human milk banks the processing applied for greater conservation is Holder pasteurization. Therefore, the objective of this work is to perform a search in the literature about new possible treatments to be applied to human milk, and its influence on its physical-chemical composition; and in this sense, the studied processes were: Holder pasteurization, lyophilization, spray-drying, high hydrostatic pressure, high temperature and short time, and short wave ultraviolet irradiation. For that, a search was performed in databases, and 126 articles were selected to carry out this review according to the keywords used. It was observed that the studied treatments can be applied for the processing and conservation of human milk, once it was applied in matrices with similar composition.

Structure-induced features of transport processes in an electroconsolidated FeNi composite

The structure and processes of mass, charge and heat transfer are investigated in an equiatomic Fe–Ni composite fabricated by electroconsolidation using the spark plasma sintering (SPS) technology. The system contains regions of almost pure Fe and Ni, separated by areas with variable concentration of components, formed in consequence of the interdiffusion in the electroconsolidation process. The interdiffusion coefficient of the Fe–Ni system has been revealed to be significantly higher than that of an alloy of a similar composition at the same temperature, which is likely the result of the employed SPS technology and the enhanced diffusion along the grain boundaries. The concentration dependence of the interdiffusion coefficient passes through a maximum at a Ni concentration of [Formula: see text] at.%. The electrical and thermal conductivity of the studied system is significantly higher than that of an alloy of the same composition. The temperature dependence of the resistivity of the sample in the range 5–300 K is due to the scattering of electrons by defects and phonons, and the scattering of electrons by phonons fits well to the Bloch–Grüneisen–Wilson relation. The boundaries of the conductivity of the investigated composite correspond to the Hashin–Shtrikman boundaries for a three-phase system, if Fe, Ni and the FeNi alloy are selected as phases.

Enrichment of heavy REE and Th in carbonatite-derived fenite breccia

Enrichment of the heavy rare earth elements (HREE) in carbonatites is rare as carbonatite petrogenesis favours the light (L)REE. We describe HREE enrichment in fenitized phonolite breccia, focusing on small satellite occurrences 1–2 km from the Songwe Hill carbonatite, Malawi. Within the breccia groundmass, a HREE-bearing mineral assemblage comprises xenotime, zircon, anatase/rutile and minor huttonite/thorite, as well as fluorite and apatite. A genetic link between HREE mineralization and carbonatite emplacement is indicated by the presence of Sr-bearing carbonate veins, carbonatite xenoliths and extensive fenitization. We propose that the HREE are retained in hydrothermal fluids which are residually derived from a carbonatite after precipitation of LREE minerals. Brecciation provides a focusing conduit for such fluids, enabling HREE transport and xenotime precipitation in the fenite. Continued fluid–rock interaction leads to dissolution of HREE-bearing minerals and further precipitation of xenotime and huttonite/thorite. At a maximum Y content of 3100 µg g−1, HREE concentrations in the presented example are not sufficient to constitute ore, but the similar composition and texture of these rocks to other cases of carbonatite-related HREE enrichment suggests that all form via a common mechanism linked to fenitization. Precipitation of HREE minerals only occurs where a pre-existing structure provides a focusing conduit for fenitizing fluids, reducing fluid – country-rock interaction. Enrichment of HREE and Th in fenite breccia serves as an indicator of fluid expulsion from a carbonatite, and may indicate the presence of LREE mineralization within the source carbonatite body at depth.

Comparative Analysis of Different Local Anesthetic Solutions Available in Market: An In Vitro and Clinical Study

Objectives The study aimed to evaluate and compare various commercially available local anesthetic solutions. Materials and Methods A total of 150 commercially available local anesthetic cartridges of similar composition (2% lidocaine with epinephrine 1:100,000) were randomly collected and divided into 3 groups. The designations of groups were selected from their product names such that each group consisted of 60 cartridges. Group S (Septodont, France) Group M (Medicaine, Korea) and Group H (HD-Caine, Pakistan). The samples were divided into five sub-groups, each consisting of 10 cartridges from each group to investigate each parameter. Results The acquired data was statistically analyzed and compared (using SPSS version 12). Compositional analysis revealed a non-significant (P>0.05) difference when the three Groups were compared with standard lidocaine and epinephrine solutions. The mean pH values of samples from group S, M and H respectively fell within the range of pH values of commercially available solutions. Non-significant difference in EPT values of Group S and H was found when efficacy was compared (p = 0.3), however a significant difference (p < 0.01) was observed in contrast to Group M. Anti-bacterial activity was observed in all the group and a non-significant difference in cell viability values of Group S and M was found (p = 0.6), while the difference was significant in comparison to Group H. Conclusion Within the limitations of these investigations, it appears that the properties of different manufacturers fall within the recommended ranges as mentioned in literature and do not appear to be statistically different in the variables we have tested.

RESEARCH OF THERMAL PROPERTIES OF UHMWPE BASED COMPOSITES AFTER EXPLOSIVE PRESSING

The thermal characteristics of the initial UHMWPE and its composites with QGP and MDF, as well as those obtained by explosive pressing (VP), have been investigated. It has been established that explosive pressing leads to hindering the processes of melting and thermal destruction, which may be associated with chemical interaction, the formation of inter- and intramolecular cross-links characteristic of this polymer. UHMWPE and its compositions with 3% CHP after VP have higher melting points of the crystalline phase, thermal oxidation and thermal destruction in comparison with the starting materials of similar composition. In the UHMWPE composition with 10% MDF, no increase in thermal properties after VP was observed, similar to the original fluoroplastic.

RESEARCH OF THERMAL PROPERTIES OF UHMWPE BASED COMPOSITES AFTER EXPLOSIVE PRESSING

The thermal characteristics of the initial UHMWPE and its composites with QGP and MDF, as well as those obtained by explosive pressing (VP), have been investigated. It has been established that explosive pressing leads to hindering the processes of melting and thermal destruction, which may be associated with chemical interaction, the formation of inter- and intramolecular cross-links characteristic of this polymer. UHMWPE and its compositions with 3% CHP after VP have higher melting points of the crystalline phase, thermal oxidation and thermal destruction in comparison with the starting materials of similar composition. In the UHMWPE composition with 10% MDF, no increase in thermal properties after VP was observed, similar to the original fluoroplastic.