Physical modeling of the laws of friction during pressure treatment is a complex problem and is solved with many restrictions and assumptions. Computational experiments open up alternative possibilities for investigating the influence of friction conditions on the rolling process. A deeper analysis of the friction mechanism in the wire block is required, since there is a significant scatter in the data on the coefficient of friction during high-speed rolling of wire rod. The aim of this work is to study the influence of friction conditions in the deformation zone of each of the stands of the wire block on the change in specific tensions, on the longitudinal stability of the rolling process, on the change in the angle of the neutral section and on the broadening of the metal. The study of the influence of these factors is based on the joint solution of the differential equilibrium equation of the elementary volume, isolated in the deformation zone, the plasticity equation. In this work, the range of variation of the coefficient of friction was chosen such as to reveal the patterns of rolling in conditions close to the limiting. The work investigated the influence of the coefficient of friction on the parameters of rolling wire rod with a diameter of 5.5 mm in a wire block. The study was carried out with a change in the coefficient of friction from 0.22 to 0.18 during the rolling of one roll. The friction conditions in the deformation zones of the wire block, affect the tension of the roll, affect both the transverse flow of the metal, and the reduction. The study of the process of rolling wire rod in a wire block showed that a toughening of the friction mode in contact between the metal and the rolls increases the longitudinal stability of the rolled wire in the deformation zone. The minimum value of the friction coefficient at which the process remains stable without loss of equilibrium is close to 0.2. With a decrease in the coefficient of friction, the tension of the metal in the inter-stand spaces sharply increases, which can lead to partial or complete slipping of the strip. The friction conditions in the contact between the rolls and the rolled stock affect the coefficient of transverse deformation and reduction of the metal in the stands of the wire block, as well as the power parameters.