Gambaran Kualitas Fungsi Penglihatan Pasien Systemic Lupus Erythematosus Berdasarkan Kuesioner NEI VFQ-25 Di Komunitas Odapus Lampung

ABSTRACT: DESCRIPTION OF THE QUALITY OF VISION FUNCTION IN SYSTEMIC LUPUS ERYTHEMA PATIENTS BASED ON THE NEI VFQ-25 QUESTIONNAIRE IN THE ODAPUS COMMUNITY OF LAMPUNGBackground: Systemic Lupus Erythematosus /Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that has characteristic manifestations or symptoms and varied clinical behavior. Eye involvement can be found in about one-third of cases of SLE, and sometimes occurs early in the disease. To assess and measure the quality of vision function in patients with Systemic Lupus Erythematosus, a measuring instrument that can be used is the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) questionnaire. Objective: To describe the quality of vision function in patients with systemic lupus erythematosus based on the NEI VFQ-25 questionnaire in the ODAPUS community in Lampung 2020. Research Methods: This research is a descriptive survey with an approach cross-sectional using primary data in the form of a questionnaire. The sample of this study was all 40 patients who joined the ODAPUS community in Lampung. Data analysis used univariate analysis using tables and graphs in data presentation. Results: The results of the study were 40 patients who met the criteria for inclusion in the study. Of the 40 patients, the patient characteristics were obtained based on the quality of vision function, namely 26-45 years (65.0%), female (97.5%), tertiary education (65.0 %), IRT (42.5%), quality of vision function is not good (90 , 0%), low-dose corticosteroids (85.0%). Conclusion: Given picture quality visual functions of patients with systemic lupus erythematosus-based questionnaire NEI VFQ-25 in the community of Lampung odapus 2020 is not good. Keywords: Quality Vision Function, SLE INTISARI: GAMBARAN KUALITAS FUNGSI PENGLIHATAN PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS BERDASARKAN KUESIONER NEI VFQ-25 DI KOMUNITAS ODAPUS LAMPUNG Latar Belakang: Lupus Eritematosus Sistemic/Systemic Lupus Erythematosus (SLE) adalah suatu penyakit autoimun multisistem yang memiliki manifestasi atau gejala khas dan perilaku klinis yang sangat bervariasi. Keterlibatan mata dapat ditemukan pada kurang lebih satu per tiga kasus SLE, dan kadang terjadi pada awal penyakit. Untuk menilai dan mengukur kualitas fungsi penglihatan pada pasien Systemic Lupus Erythematosus, alat ukur yang dapat digunakan yaitu dengan kuesioner National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25).Tujuan: Untuk mengetahui gambaran kualitas fungsi penglihatan pasien systemic lupus erythematosus berdasarkan kuesioner NEI VFQ-25 di komunitas ODAPUS Lampung 2020.Metode Penelitian: Jenis penelitian ini adalah survei deskriptif dengan pendekatan Cross- sectional menggunakan data primer berupa kuesioner. Sampel penelitian ini adalah seluruh pasien yang bergabung di komunitas ODAPUS Lampung sebanyak 40 orang. Analisis data menggunakan analisis univariat dengan menggunakan tabel dan grafik dalam penyajian data.Hasil: Hasil penelitian terdapat 40 pasien yang memenuhi kriteria untuk dimasukkan dalam penelitian. Dari 40 pasien tersebut didapatkan karakteristik pasien berdasarkan kualitas fungsi penglihatan yaitu terbanyak pada usia 26-45 tahun (65,0%), jenis kelamin perempuan (97,5%), pendidikan perguruan tinggi (65,0%), pekerjaan IRT (42,5%), kualitas fungsi penglihatan tidak baik (90,0%), dan penggunaan kortikosteroid dosis rendah (85,0%). Kesimpulan: Gambaran kualitas fungsi penglihatan pasien systemic lupus erythematosus berdasarkan kuesioner NEI VFQ-25 di komunitas ODAPUS Lampung 2020 yaitu tidak baik. Kata Kunci : Kualitas Fungsi Penglihatan, SLE

Associations between Visual, Hearing Functioning and Cognitive Functioning among Hispanics/Latinos

Findings that visual impairment (VI) and hearing impairment (HI) are associated with cognitive functioning are drawn from studies that involved few Hispanic/Latino participants. We utilized data from the Miami Ocular SOL ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) with 1056 participants aged 45 and older. The outcomes were neurocognitive performances assessed by the Digit Symbol Substitution Test (DSST, executive function), Word Frequency Test (verbal fluency), Brief Spanish-English Verbal Learning Test-recall (B-SEVLT recall, episodic memory), and the Six-Item Screener (global cognitive functioning). Visual functioning was measured by National Eye Institute Visual Function Questionnaire (NEI-VFQ). Hearing function which was measured by Hearing Handicap Inventory for Adults and Elderly (HHIA/HHIE) was available for all HCHS/SOL participants (n=9343). Multiple regression was performed for each cognitive outcome while controlling for age, gender, education, Hispanic/Latino ethnicity background, cardiovascular risk factors, depression and complex design. NEI-VFQ was associated with 3 of the 4 cognitive outcomes: DSST (β =0.14, se=0.027, p<0.01), Word Frequency Test (β=0.042, se=0.016, p<0.01), B-SEVLT-recall (β=0.021, se=0.007, p<0.03). HHIA/HHIE was not associated with any of the cognitive measures examined. The HHIA/HHIE analysis was repeated using data from all sites; similar results were observed. Visual functioning but not hearing functioning is associated with worse cognition in Hispanics/Latinos, although previous HCHS/SOL analysis indicated that hearing loss as assessed by pure tone audiometry was associated with worse cognitive functioning. Longitudinal assessment of both clinical and functional measures is needed to understand the impact of sensory impairment on cognition in Hispanics/Latinos.

Broad and Long-Lasting Vision Improvements in Youth With Infantile Nystagmus After Home Training With a Perceptual Learning App

Current treatments for infantile nystagmus (IN), focused on dampening the oscillating eye movements, yield little to no improvement in visual functioning. It makes sense, however, to treat the visual impairments associated with IN with tailored sensory training. Recently, we developed such a training, targeting visual crowding as an important bottleneck in visual functioning with an eye-movement engaging letter discrimination task. This training improved visual performance of children with IN, but most children had not reached plateau performance after 10 supervised training sessions (3,500 trials). Here, we evaluate the effects of prolonged perceptual learning (14,000 trials) in 7-18-year-old children with IN and test the feasibility of tablet-based, at-home intervention. Results demonstrate that prolonged home-based perceptual training results in stable, long lasting visual acuity improvements at distance and near, with remarkably good transfer to reading and even stereopsis. Improvements on self-reported functional vision scores underline the clinical relevance of perceptual learning with e-health apps for individuals with IN.

Predicting changes in cataract surgery health outcomes using a cataract surgery appropriateness and prioritization instrument

Objective Determine whether items in a cataract surgery appropriateness and prioritization questionnaire can predict change in best corrected visual acuity (BCVA) and health related quality of life (HRQOL) following cataract surgery. Methods 313 patients with a cataract in Ontario, Canada were recruited to participate. BCVA was measured using the Snellen chart. HRQOL was measured using a generic instrument (EQ5D), a visual functioning instrument (Catquest-9SF), and an appropriateness and prioritization instrument (17 items). Outcomes were measured preoperatively and 3–6 months postoperatively. Descriptive statistics were used to describe demographics and outcomes. For each appropriateness and prioritization questionnaire item, a one-way ANOVA was used to compare group means of the change in BCVA, EQ5D, and Catquest-9SF. Results Participants had a mean age of 69 years and were 56% female. BCVA improved in 81%, EQ5D in 49.6%, and Catquest-9SF score in 84% of patients. Improvement in both BCVA and Catquest-9SF scores were found in 68.5% of patients. The ANOVA showed a statistically significant association between a change in BCVA and the ability to participate in social life, and a statistically significant association between a change in Catquest-9SF and glare, extent of impairment in visual function, safety and injury concerns, ability to work and care for dependents, ability to take care of local errands, ability to assist others and ability to participate in social life. Conclusions Almost all patients had improved BCVA and/or visual functioning after surgery. Seven variables from the cataract appropriateness and prioritization instrument were found to be predictors of improvement in Catquest-9SF measuring visual functioning.

A qualitative exploration of the early signs of cerebral visual impairment in preschool children

Aim: To explore which signs in visual functioning and visual behaviour in preschool children at risk for cerebral visual impairment (CVI) can potentially be early signs for a diagnosis at a later age.Methods: Thematic analysis of interviews with seven experts in the field of CVI and of a focus group with nine parents of five children with confirmed or suspected CVI.Results: Our experts and parents identified five likely early signs of CVI in preschool children with developmental impairments and brain injury who are at risk for CVI. They suggest that preschool children with CVI display atypical ways of coping with complex situations and of navigating their surroundings. Children also show impaired multisensory integration according to our interviewees. Furthermore, their visual responses often vary even when the stimulus remains the same or they might display impairments in visual recognition and identification.Interpretation: We have proposed five signs in visual functioning and visual behaviour in preschool children at risk for CVI that may be early signs for a diagnosis of CVI at a later age. This exploration can guide future retrospective and longitudinal research on diagnosing CVI at a young age. Early diagnosis and subsequent early intervention have a positive impact on learning and development of infants with disabilities.