Associations between Visual, Hearing Functioning and Cognitive Functioning among Hispanics/Latinos

Findings that visual impairment (VI) and hearing impairment (HI) are associated with cognitive functioning are drawn from studies that involved few Hispanic/Latino participants. We utilized data from the Miami Ocular SOL ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) with 1056 participants aged 45 and older. The outcomes were neurocognitive performances assessed by the Digit Symbol Substitution Test (DSST, executive function), Word Frequency Test (verbal fluency), Brief Spanish-English Verbal Learning Test-recall (B-SEVLT recall, episodic memory), and the Six-Item Screener (global cognitive functioning). Visual functioning was measured by National Eye Institute Visual Function Questionnaire (NEI-VFQ). Hearing function which was measured by Hearing Handicap Inventory for Adults and Elderly (HHIA/HHIE) was available for all HCHS/SOL participants (n=9343). Multiple regression was performed for each cognitive outcome while controlling for age, gender, education, Hispanic/Latino ethnicity background, cardiovascular risk factors, depression and complex design. NEI-VFQ was associated with 3 of the 4 cognitive outcomes: DSST (β =0.14, se=0.027, p<0.01), Word Frequency Test (β=0.042, se=0.016, p<0.01), B-SEVLT-recall (β=0.021, se=0.007, p<0.03). HHIA/HHIE was not associated with any of the cognitive measures examined. The HHIA/HHIE analysis was repeated using data from all sites; similar results were observed. Visual functioning but not hearing functioning is associated with worse cognition in Hispanics/Latinos, although previous HCHS/SOL analysis indicated that hearing loss as assessed by pure tone audiometry was associated with worse cognitive functioning. Longitudinal assessment of both clinical and functional measures is needed to understand the impact of sensory impairment on cognition in Hispanics/Latinos.

P–517 The relationship between mitochondrial gene CYB (MT-CYB) single nucleotide polymorphisms and male infertility

Study question Do single nucleotide polymorphisms of the mitochondrial gene CYB (MT-CYB) affect male fertility? Summary answer there was a significant association between male fertility and rs527236194, rs28357373, and rs41504845 single nucleotide polymorphisms of the mitochondrial gene CYB (MT-CYB). What is known already Male infertility can be occurred as a result of various factors. However, genetic factors are detected in 15% of male infertility cases and can be classified into two groups: chromosomal abnormalities and single gene mutations. Sperm mitochondrial DNA alterations may have serious effects on spermatogenesis, sperm motility and the ability of sperm to fertilize the oocyte. Mutations of the MT-CYB gene might lead to various disorders and deficiencies specially in complex III which might interrupt in the ATP production process. Study design, size, duration: 111 semen samples were included in this prospectively designed study which carried out between 2017 and August 2019. Participants/materials, setting, methods: This study carried out at the Department of Obstetrics and Gynecology at Saarland University, Germany. Samples were divided into 67 subfertile “cases” and 44 fertile “control” groups. After preparation of semen samples by density gradient centrifugation, nuclear and mitochondrial DNA (MT-DNA) was extracted using QIAamp DNA Mini Kit from QIAGEN. Thereafter, the MT-DNA was amplified using REPLI-g Mitochondrial DNA Kit from QIAGEN, followed by PCR and Sanger sequencing steps. Main results and the role of chance A total of 13 single nucleotide polymorphisms (SNPs) in the MT-CYB gene in each of the case and control groups were detected. Eight SNPs were non-synonymous variants including: rs2853508, rs28357685, rs41518645, rs2853507, rs28357376, rs35070048, rs2853506, and rs28660155 and five SNPs were synonymous variants: rs527236194, rs28357373, rs28357369, rs41504845, and rs2854124.Among these SNPs, three of them showed a significant difference in the genotype’s frequency test between sub-fertile and fertile groups: rs527236194 (T15784C; P = 0.0005), rs28357373 (T15629C; P = 0.0439), and rs41504845 (C15833T; P = 0.0038). For the allele’s frequency test, two SNPs were significant: rs527236194 (T15784C; P = 0.0014) and rs41504845 (C15833T; P = 0.0147). Limitations, reasons for caution The study population size Wider implications of the findings: A larger prospective study will be required to confirm the associations between these mitochondrial gene polymorphisms in MT-CYB (rs527236194, rs28357373, rs41504845) and male infertility and to clarify the definite effect of the mitochondrial genetic variations on male infertility. Trial registration number Not applicable

Teknik yang paling dominan pada pertandingan futsal putra profesional

Penelitian ini bertujuan untuk mengetahui teknik yang paling dominan digunakan pada pertandingan futsal putra profesional. Penelitian ini termasuk pada jenis kuantitatif dengan metode survei. Sampel yang digunakan berjumlah empat tim liga futsal putra profesional dengan teknik pengambilan sampel yang digunakan adalah purposive sampling. Analisis data menggunakan uji frekuensi dan prosentase dari teknik yang paling sering digunakan. Hasil dari penelitian ini menunjukkan bahwa frekuensi penggunaan teknik passing sebanyak 2181 kali, control sebanyak 1853 kali, dribbling sebanyak 422 kali, shooting sebanyak 238 kali, feinting sebanyak 92 kali, heading sebanyak 25 kali, shielding sebanyak 56 kali, turning sebanyak 17 kali, dan chipping sebanyak 37 kali. Sedangkan prosentase penggunaan teknik passing sebesar 44%, control sebesar 37%, dribbling sebesar 9%, shooting sebesar 5%, feinting sebesar 2%, heading sebesar 1%, shielding sebesar 1%, turning sebesar 0%, dan chipping sebesar 1%. Berdasarkan hasil tersebut dapat disimpulkan bahwa terdapat dua teknik yang sangat dominan dalam pertandingan futsal putra professional yaitu teknik passing dan control. The most dominant technique in professional men’s futsal matches AbstractThis study discusses the most dominant technique used in professional men's futsal matches. This research is a quantitative type with the survey method. The sample used took four professional men's futsal league teams with the sampling technique used was purposive sampling. Data analysis uses a frequency test and the percentage of the most frequently used techniques. The results of this study resulted in passing 2181 times, control 1853 times, dribbling 422 times, shooting 238 times, feinting 92 times, heading 25 times, shielding 56 times, turning 17 times, and chipping 37. While the percentage of the use of passing techniques by 44%, control by 37%, dribbling by 9%, shooting by 5%, feinting by 2%, heading by 1%, shielding by 1%, turning by 0%, and chipping by 1%. Based on these results it can be concluded that there are two techniques that are very dominant in professional men's futsal matches, namely passing and control techniques.

Предельные совместные распределения статистик трех критериев пакета NIST

Найдены совместное распределение и предельное совместное распределение статистик следующих критериев пакета NIST: «Monobit Test», «Frequency Test within a Block» и «Cumulative Sums Test» в случае, когда исследуемая последовательность имеет распределение Бернулли. В случае, когда в критерии «Frequency Test within a Block» используются два блока, найдены попарные ковариации данных статистик.

Предельные совместные распределения статистик четырех критериев пакета NIST

Найдено предельное совместное распределение статистик следующих критериев пакета НИСТ: «Monobit Test», «Frequency Test within a Block», «Runs Test» и обобщения критерия шаблонов «Non-overlapping Template Matching Test» в ситуации, когда исследуемая последовательность является бернуллиевской с параметром $p$. Отдельно рассматривается случай $p=\frac12 $. Установлены необходимые и достаточные условия асимптотической некоррелированности, а также необходимые и достаточные условия асимптотической независимости рассматриваемых статистик.

Integrated estimation of parameters of radio transmitter power amplifier with automatic mode adjustment by two-frequency test signal

Comparative estimation of energy parameters of power amplifiers of single-band radio transmitters using automatic mode adjustment using a deterministic two-frequency test signal instead of a random single-band signal modulated by speech is investigated in the work. Relationships are found that allow judging the power consumption of the terminal stage of the power amplifier with automatic mode adjustment under various types of modulation based on the results of measurements obtained during tests. The ratios between the power consumption of the output stage when amplifying the random speech signal and amplifying the deterministic two-frequency test signal are obtained both without taking into account losses in the controlled power supply and taking into account such losses. Method is proposed for calculation of energy gain and efficiency factor (efficiency) when applying automatic control of supply voltage of output cascades of shortwave transmitters intended for modulation with speech signals. The loss in the regulated power supply has been estimated. The advantage of power amplifier circuits with automatic mode adjustment is justified

Encryption Image by Using RC6 and Hybrid Chaotic Map

Cryptography is data processed in a way that becomes incomprehensible and unavailable to unauthorized persons. In this paper instructed method to encryption image by using RC6 algorithm and generated key by using hybrid chaotic map (tent and logistic map). Used some measures such as frequency test within a block, entropy, serial test (two-bit test), and frequency test (monobit test); to demonstrate the strength of the algorithm proposed in the image coding and protection. The MATLAB program was used as a work environment.