Coumarin Derived Schiff Base Ligand-Synthesis, Characterization and Antimicrobial Study of its Metal Complexes.

A novel ligand was synthesized from terephthalaldehyde and o-phenylene diamine and treated with coumarin derivative to form a New Schiff base. Co(II), Ni(II) and Cu(II) complexes of the ligand were synthesized. 1HNMR and LC-MS mass spectrometry studies were done. Antimicrobial studies were performed for the ligand and its metal complex with E.Coli and was found to be active. The ligand can be further modified and studied for its antimicrobial action in the future.

Synthesis and Antimicrobial Study of Thiophene Clubbed Thiazolyl Carbohydrazides

Thiophene containing thiazolyl carbohydrazide on reaction with various aryl isothiocynates yields thiosemicarbazides which were transformed into 1,2,4- substituted thiazoles by Hantzsch synthesis and characterized by spectral methods. Most of the synthesized new thiosemicarbazides are found to be promisingly effective against tested bacterial strains and exhibited moderate activitytested fungal strains. Most of the 1, 2,4- substituted thiazoles are weakly active against test organisms.

Pharmaceutical Preparation of Arka Lavan and Assessment for Its Analytical Study

Background: Arka is commonly found plant in India. It is mostly used for religious purpose in India. In Ayurved, it has in used for various medical preparation. One of such preparation is Arka Lavan. Aim: Pharmaceutico-analytical study of Arka lavan& evaluation for Antimicrobial study Materials: The raw materials Arka patra will be collected from the medicinal plant garden, of Mahatma Gandhi Ayurved College , Hospital & research centre, Salod ( H), wardha. The arka patra will be authenticated by Dravyaguna department. The another raw material is Saindhava Lavan will be procured from Dattatraya Ayurved Rasashala and will be authenticated by Rasashastra & Bhaishajya kalpana Department Arka lavan will be prepared as per the reference.The prepared Arka lavan will be analyzed. Observation and Results: The Arka patra lavan will be assessed for organoleptic, physicochemical and TLC parameters Conclusion: The pharmaceutical & analytical study of Arka lava will provide the standard parameters.