scholarly journals Pharmaceutical Preparation of Arka Lavan and Assessment for Its Analytical Study

2021 ◽  
pp. 81-85
Author(s):  
S. Sheikh ◽  
A. Wanjari ◽  
S. Kamble ◽  
S. Wankhede ◽  
D. Wanjari ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Analytical Study ◽  
Raw Materials ◽  
Pharmaceutical Preparation ◽  
Raw Material ◽  
Research Centre ◽  
College Hospital ◽  
Mahatma Gandhi ◽  
Medical Preparation ◽  
Antimicrobial Study

Background: Arka is commonly found plant in India. It is mostly used for religious purpose in India. In Ayurved, it has in used for various medical preparation. One of such preparation is Arka Lavan. Aim: Pharmaceutico-analytical study of Arka lavan& evaluation for Antimicrobial study Materials: The raw materials Arka patra will be collected from the medicinal plant garden, of Mahatma Gandhi Ayurved College , Hospital & research centre, Salod ( H), wardha. The arka patra will  be authenticated by Dravyaguna department. The another raw material is Saindhava Lavan will be procured from Dattatraya Ayurved Rasashala and will be authenticated by Rasashastra & Bhaishajya kalpana Department Arka lavan will be prepared as per the reference.The prepared Arka lavan will be analyzed. Observation and Results: The Arka patra lavan will be assessed for organoleptic, physicochemical and TLC parameters  Conclusion: The pharmaceutical & analytical study of Arka lava will provide the standard parameters.

TECHNOLOGY FOR OBTAINING PECTIN CONCENTRATE FROM ROSEHIP FRUITS

2021 ◽  
pp. 87-90
Author(s):  
М.Ж. Кизатова ◽  
Д.А. Абдуллаева
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Plant Raw Material ◽  
Pectin Substances

Статья посвящена важности пектиновых веществ, а также расширению сферы использования лекарственного растительного сырья. В качестве лекарственного растительного сырья представлены технологии получения пектинового экстракта из плодов шиповника, которые встречаются на территории Казахстана 25 видов. Применение пектина в медицине. The article is devoted to the importance of pectin substances, as well as to the expansion of the use of medicinal plant raw materials. As a medicinal plant raw material, technologies for obtaining pectin extract from rosehip fruits, which are found in 25 species on the territory of Kazakhstan, are presented. The use of pectin in medicine

scholarly journals Agro-Morphological, Microanatomical and Molecular Cytogenetic Characterization of the Medicinal Plant Chelidonium majus L.

Plants ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 1396
Author(s):  
Tatiana E. Samatadze ◽  
Olga Y. Yurkevich ◽  
Firdaus M. Hazieva ◽  
Elena A. Konyaeva ◽  
Alexander I. Morozov ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Morphological Variability ◽  
5S Rdna ◽  
Raw Material ◽  
Chelidonium Majus ◽  
Diagnostic Features ◽  
Molecular Cytogenetic ◽  
Cytogenetic Characterization ◽  
First Time

Chelidonium majus L. is a medicinal plant well-known as a valuable source of isoquinoline alkaloids, which has a variety of pharmacological properties including anti-viral and anti-bacterial effects. However, considerable intraspecific bio-morphological variability in C. majus complicates raw material identification and verification. For the first time, we have brought into cultivation five populations of C. majus subsp. majus originated from different regions, and performed their agro-morphological, microanatomical and molecular cytogenetic characterization. All examined populations produced high seed (18.6–19.9 kg/ha) and raw material (0.84–1.08 t/ha) yields; total alkaloid contents were within 0.30–0.38%. Nevertheless, significant differences in plant morphology and yield-contributing traits were observed. The performed microanatomical analysis of leaves and flowers in double- and normal-flowered plants revealed micro-diagnostic features (including tissue topography, types of stomata, laticifers, structure of leaf mesophyll, hairs, sepals and petals) important for identification of C. majus raw materials. The analysis of chromosome morphology, DAPI-banding patterns, FISH mapping of 45S and 5S rDNA and also chromosome behavior in meiosis allowed us to identify for the first time all chromosomes in karyotypes and confirm relative genotype stability of the studied plants. Our findings indicate that the examined C. majus populations can be used in further breeding programs.

scholarly journals Medicinal flora of the Middle Urals – a prospective source of obtaining medicines

2021 ◽  
Vol 10 (4) ◽  
pp. 32-36
Author(s):  
A. Yu. Turyshev ◽  
V. D. Belonogova ◽  
A. A. Orlova ◽  
K. O. Sidorov ◽  
A. Yu. Skornyakova
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Quantitative Assessment ◽  
Raw Materials ◽  
The State ◽  
Raw Material ◽  
Middle Urals ◽  
The Middle Urals ◽  
Plant Raw Materials ◽  
Medicinal Flora

Introduction. Medicinal plant raw materials are one of the most important sources of herbal remedies used both for the prevention and treatment of a number of diseases [1, 2]. Even with the development of modern science and chemistry, medicinal plant raw materials are widely used in both folk and official medicine. The advantage of medicinal plants is their wide range of biological activity, low toxicity and the possibility of long-term use without significant side effects. Human economic activity has a noticeable negative effect on the condition of wild-growing plants: their stocks are decreasing, and some species disappear altogether. Today, given the high level of development of industry and agriculture, the procurement of raw materials for wild medicinal plants is not always possible. Information on the quantitative assessment of the raw material base of wild medicinal plants in the Middle Urals, the content of biologically active substances in medicinal plant raw materials is partially outdated, which determines the need for their systemic resource study and chemical-pharmacognostic study.Aim. Comprehensive assessment of the state of populations of wild medicinal plants in the Middle Urals.Materials and methods. Determination of stocks of raw materials of the studied species of medicinal plants was carried out on specific thickets according to the generally accepted method. The authenticity of the raw materials was established by a macroscopic method when collecting raw material samples. In the course of the study, samples of medicinal plant materials of 5 types were prepared. The determination and assessment of the main indicators of the good quality of medicinal plant raw materials (the content of active and extractive substances, moisture in the mass upon drying, total ash and ash insoluble in a 10% solution of hydrochloric acid) was carried out according to the methods and requirements of the State Pharmacopoeia of the Russian Federation XIV edition. In the raw materials Artemisiae absinthii herba and Leonuri herba, the amount of extractives was determined by the gravimetric method. The quantitative assessment of the content of essential oil in the samples of Origani vulgaris herba and Tanaceti vulgaris flores was carried out by the method of hydrodistillation. To determine the quantitative content of the sum of flavonoids in Hyperici herba, Artemisiae absinthii herba, Leonuri herba and the sum of flavonoids and phenolcarboxylic acids in Tanaceti vulgaris flores, a spectrophotometric method was used.Results and discussion. In the course of resource and phytochemical studies of representatives of the medicinal flora of the Middle Urals, a comprehensive assessment of the state of populations of wild medicinal plants – sources of medicinal plant raw materials (Origani vulgaris herba, Hyperici herba, Tanaceti vulgaris flores, Artemisiae absinthii herba and Leonuri herba) was carried out. The results are included in the electronic inventory of wild medicinal plants of the Middle Urals.Conclusion. The conducted complex of studies will allow updating information about the medicinal flora of the Middle Urals in order to use raw materials for the creation of medicines.

scholarly journals Transformations of Metal Supply during the Bronze Age in the Carpathian Basin

2020 ◽  
Vol 9 (2) ◽  
pp. 315-330
Author(s):  
Viktória Kiss
Keyword(s):  
Bronze Age ◽  
Neutron Radiography ◽  
Raw Materials ◽  
Isotope Analysis ◽  
Carpathian Basin ◽  
Raw Material ◽  
Research Centre ◽  
Metal Artifacts ◽  
Mining Sites ◽  
The Bronze Age

This paper presents recent research questions which have been raised and methods which have been used in the study of Bronze Age metallurgy in connection with available natural resources (ores) in and around the Carpathian Basin. This topic fits in the most current trends in the research on European prehistoric archaeology. Given the lack of written sources, copper and bronze artifacts discovered in settlement and cemetery excavations and prehistoric mining sites provide the primary sources on which the studies in question are based. The aim of compositional and isotope analysis of copper and tin ores, metal tools, ornaments, and weapons is to determine the provenience of the raw materials and further an understanding of the chaine operatiore of prehistoric metal production. The Momentum Mobility Research Group of the Institute of Archaeology, Research Centre for the Humanities studies these metal artifacts using archaeological and scientific methods. It has focused on the first thousand years of the Bronze Age (2500–1500 BC). Multidisciplinary research include non-destructive XRF, PGAA (promptgamma activation), TOF-ND (time-of-flight neutron diffraction) analyses and neutron radiography, as well as destructive methods, e.g. metal sampling for compositional and lead isotope testing, alongside archaeological analysis. Microstructure studies are also efficient methods for determining the raw material and production techniques. The results suggest the use of regional ore sources and interregional connections, as well as several transformations in the exchange network of the prehistoric communities living in the Carpathian Basin.

scholarly journals Quality Numerical Indicators of Raw Materials of Sanguisorba Officinalis L. Growing on Overburden Dumps of Kuzbass Coal Surface Mines

2019 ◽  
Vol 105 ◽  
pp. 02004
Author(s):  
Natalya Egorova ◽  
Irina Egorova ◽  
Elena Maltseva ◽  
Andrey Sukhikh
Keyword(s):  
Heavy Metals ◽  
Medicinal Plant ◽  
Coal Mine ◽  
Raw Materials ◽  
Raw Material ◽  
Open Pit ◽  
Normal Range ◽  
Plant Materials ◽  
Sanguisorba Officinalis ◽  
Overburden Dumps

Medicinal plant materials quality assessment of the Sanguisorba officinalis L. growing on the Kedrovsky coal mine dumps in Kemerovo region is given. The analysis of obtained burnet raw material quality indicators (moisture, total ash, insoluble in hydrochloric acid, quantitative content of tannins, heavy metals, radionuclides) showed that this vegetable raw material match with the requirements of PhI.2.5.0078.18 “Sanguisorba officinalis L. rhizome and roots”. Tannins average content in the burnet rhizomes and roots was 15.708 ± 0.307%, which is within the normal range (up to 14%). It was found that the heavy metals (Pb, Cd, Hg) content does not exceed the MPC adopted for medicinal plant raw materials (G.Ph.A.5.5.000.0009.15). The obtained indicators for the artificial radionuclides (Cs-137, Sr-90) content showed that their quantity in the raw material is also within the normal range and their actual content is several times less than the normalized one. From the point of radiological safety view the studied raw materials are not dangerous since they accumulate 0.36% Sr-90 and 0.42% Cs-137 from the levels established by regulatory documentation. Therefore, the burnet medicinal plant raw material harvested at the Kedrovsky open-pit coal mine on the territory of waste dump does not represent a danger to human health.

scholarly journals Development of approaches to standardization of black walnut bark

2020 ◽  
Vol 20 (1-2) ◽  
pp. 131-136
Author(s):  
Natalya I. Zimenkina ◽  
Vladimir A. Kurkin
Keyword(s):  
Medicinal Plant ◽  
Quantitative Determination ◽  
Raw Materials ◽  
Juglans Regia ◽  
Black Walnut ◽  
Juglans Nigra ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Plant Raw Material

Significance. Black Walnut (Juglans nigra L.) is a species of trees of the Walnut family (Juglandaceae). This plant of the genus Walnut (Juglans L.) has not been sufficiently studied unlike other species e.g. Juglans regia L. This medicinal plant raw material is quite perspective, its preparations have antimicrobial, general tonic effect. We can use its leaves, unripe fruit, and the bark. However they are not widely used in medicine. In order to introduce the plants of the Walnut genus to the State Pharmacopoeia of the Russian Federation (RF State Pharmacopoeia), it is necessary to conduct of pharmacognostic studies, to develop product specification file to confirm the identification and quality of medicinal plant raw materials. The aim of this study is to develop a method of quantitative determination of flavonoids in the bark of the black walnut (Juglans nigra L.). Materials and methods. Material of the study was black walnut bark, stocked during the sap flow period (April) in 2018. The bark was skived up to 15 cm long and 23 cm wide. The bark was air-dried with the protection from direct sun light. The end of the drying was checked by the brittleness of the bark. Results. The methods of the quantitative determination of flavonoids in walnut bark has been developed. We used the differential spectrophotometry taking into consideration state standard sample of rutin at the analytical wavelength of 416 nm. The error of a single determination with a confidence level of 95% is 1.20%. Conclusion. We used the developed technique and analyzed a number of samples of black walnut bark. The content of total flavonoids in the plant raw material is 5.13 0.02% (as calculated on rutin). The flavonoid content should be at least 4.0%.

scholarly journals Investigation of Walnut Herbal Drug Raw Material

2019 ◽  
Vol 8 (4) ◽  
pp. 38-46
Author(s):  
N. V. Chebyshev ◽  
A. V. Strelyaeva ◽  
D. I. Lezhava ◽  
A. N. Luferov ◽  
N. V. Bobkova ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Juglans Regia ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Alcohol Extract ◽  
Plant Raw Materials ◽  
Active Substances

Introduction. Walnut (Juglans regia L.) is a medicinal plant containing a large number of biologically active substances. A number of authors propose to use walnut leaves as medicinal raw materials, in which juglone, flavonoids, tannins, ascorbic acid and other substances are identified. Currently, a standardization technique for this type of raw material has been developed and proposed. However, the medicinal plant walnut can be a source of other types of raw materials, such as milky-waxed walnuts, walnut bark, and walnut partitions. These types of medicinal raw materials contain a large number of biologically active substances and have a great potential for pharmacological activity. Therefore, the study with the subsequent standardization of medicinal plant material of walnut fruits in the stage of milk-wax ripeness and walnut bark is relevant.Aim. The aim of the study is to study the external signs, microscopy of raw walnut bark and walnut fruit in the stage of milky-wax ripeness and chemical composition of alcohol extract from these types of raw materials.Materials and methods. Chromato-mass spectrometry and TLC were used in the work.Results and discussion. When describing external signs and microscopy, diagnostic signs of both whole and crushed raw materials, and powder of walnut bark, and fruits of walnut in the stage of milky-wax ripeness were revealed. Alcohol extract obtained from medicinal plant raw materials walnut bark is a clear brown liquid. Alcohol extract obtained from medicinal plant raw materials of walnut fruit at the stage of milky-wax ripeness is a transparent, green-brown liquid with a fragrant odor.Conclusion. Gallic acid was identified by TLC in walnut bark. Chromato-mass spectrometry in alcohol extraction from the fruit of walnut in the stage of milky-wax maturity was able to identify 17 compounds belonging to different classes of biologically active substances. Sugars, flavonoids, coumarin phenolic compounds, organic acids were identified. In alcoholic extraction from the bark of a walnut, marker compounds have been determined, the combination of which makes it possible to quickly identify this type of raw material using chromatography-mass spectrometry. 

scholarly journals FLAVONOIDS FROM THE BUDS OF THE HORSE CHESTNUT (AESCULUS HIPPOCASTANUM L.)

2020 ◽  
pp. 123-129
Author(s):  
Vladimir Aleksandrovich Kurkin ◽  
Pavel Viktorovich Belov
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Uv Spectroscopy ◽  
Raw Material ◽  
Aesculus Hippocastanum ◽  
Horse Chestnut ◽  
Plant Raw Materials ◽  
Wide Range ◽  
New Type ◽  
First Time

The buds of horse chestnut (Aesculus hippocastanum L., Hippocastanaceae family) is a new promising species of medicinal plant raw material. The prospect of studying the buds of this plant is due to the content of flavonoids in them, which have a wide range of pharmacological effects. Flavonoids are interesting for their capillary-strengthening action, which allows them to be used in the treatment of chronic venous insufficiency. This fact is consistent with the practice of using drugs from other organs of horse chestnut (seeds, leaves) as venotonic and angioprotective drugs. In addition, flavonoids are also characterized by antioxidant, anti-inflammatory, antimicrobial and antifungal activity. The actuality of the study of horse chestnut buds as a new type of medicinal plant material is also supported by the need to develop of the new effective and safe drugs based on the raw materials of this plant. The aim of this study was to determine the flavonoid composition of the buds of Aesulus hippocastanum. In the course of the work from the buds of horse chestnut by the method of column chromatography on silica gel L 100/160 was for the first time there were isolated and characterized using 1H-NMR, 13C-NMR, UV spectroscopy and mass spectrometry the flavonoid compounds rhamnocitrin (7-O-methylkaempferol), and accompanying 7,4′-dimethylkaempferol. The dominant and diagnostic significant flavonoid for the horse chestnut buds is rhamnocitrin. The results indicate the prospects for further study of the buds of the horse chestnut as a new type of medicinal plant raw materials.

scholarly journals MINERAL AND AMINO ACID COMPOSITION OF THE LEAVES OF MYRTHUS COMMUNIS L.

2019 ◽  
pp. 217-223
Author(s):  
Ekaterina Yur'yevna Bakova ◽  
Yuriy Vladimirovich Plugatar ◽  
Nadezhda Nikolayevna Bakova ◽  
Dmitriy Alekseyevich Konovalov
Keyword(s):  
Heavy Metals ◽  
Amino Acids ◽  
Amino Acid ◽  
Medicinal Plant ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Raw Materials ◽  
Raw Material ◽  
Botanical Gardens ◽  
Promising Source

The homeland of Myrthus communis L. is Mediterranean region, in the countries of which its wild-growing and cultivated varieties grow. In the collection of the Nikitsky Botanical Gardens – National Scientific Center of the Russian Academy of Sciences the economic-valuable and morphological features of nine cultivars of this species have been studied. The plant is considered as a promising industrial medicinal culture. Contamination of medicinal plants with heavy metals and other toxic elements is an existing problem, which is associated with serious concern of international organizations on the quality and safety of medicinal raw materials. It is now established that trace constituents, entering into connection with chemical regulators of metabolism, including amino acids, participate in various biochemical processes, stimulate and normalize metabolism. The objective of this work is to study the elemental and amino acid composition of leaves of Myrthus communis L., cultivated in the Nikitsky Botanical Gardens. The study of Myrthus communis L. ultimate composition has been done with due regard to General Monograph requirements "The identification of heavy metals and arsenium in medicinal raw materials and plant preparations" for State Pharmacopeia of XIII edition. The research of the amino acid profile has been done subject to State All-Union Standard 32195-2013 (ISO 13903:2005). As a result of research it has been established that leaves of Myrthus communis L. accumulate 28 elements and 16 amino acids. The content of heavy metals and arsenium in the studied samples did not exceed the maximum permissible values for medicinal plant raw materials established by the Russian State Pharmacopoeia. The total content of amino acids in the leaves of myrtle was 11.65%. Among the amino acids found, glutamic and aspartic acids prevailed. The least in the leaves was methionine. The obtained results will be used for follow up standardization of myrtle raw materials as a promising source of medicinal plant raw material.

scholarly journals Pulsatilla alba: analytical review of spread, chemical composition, biological activity and medical application

2021 ◽  
pp. 10-14
Author(s):  
Anna Krvavych ◽  
Nataliia Reviakina ◽  
Lesia Zhurakhivska ◽  
Iryna Hubytska ◽  
Roksolana Konechna
Keyword(s):  
Chemical Composition ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Folk Medicine ◽  
Medical Application ◽  
Biologically Active ◽  
Raw Material ◽  
Sources Of Information ◽  
Scientific Publications ◽  
Plant Raw Materials

The object of analytical study is the medicinal plant Pulsatilla alba. This species is rare, the stocks of herbal raw materials are limited, and there are no Pulsatilla alba-based medicines on the Ukrainian market. The aim of study was to analyze and summarize data on the range, content of biologically active compounds and the spectrum of use in pharmacy and medicine Pulsatilla alba. Materials and methods. Literary and electronic sources of information on the distribution, chemical composition and pharmacological activity of Pulsatilla alba. Results. Pulsatilla alba is a plant of the Ranunculaceae family, characterized by a high content of biologically active organic compounds, namely organic acids, traces of alkaloids, vitamins, resinous and tannins, about 20 different macro-and micronutrients, essential oils, γ-lactones, triterpenoids, sterols, chelidonic acid, coumarins, as well as giving it protection status make it an interesting object for research. Analysis of scientific publications revealed that plants of the family Ranunculaceae, in particular, Pulsatilla alba contain a significant amount of biologically active substances, have numerous pharmacological activities, have long been used in folk medicine, and is a promising raw material for the production of phytopreparations. The volume of processing of medicinal plant raw materials in Ukraine in one year is from 5 to 6 thousand tons, the amount of raw materials for export reaches more than 3 thousand tons per year. About 1,000 tons of raw materials consumed in Ukraine are imported and 1,500 tons are domestically produced. Conclusions. Therefore, as populations of rare low-competitive species of the Ranunculaceae family are particularly endangered, displaced by tree, shrub and highly competitive trivial violent herbaceous species due to the widespread use of Pulsatilla alba in folk medicine as an antitumor, hypnotic, hypnotic, antifungal, antifungal research which should be continued

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