A Novel Technique for the Fabrication of Hollow Denture - A Need for Resorbed Ridge

Removable prosthesis is probably one of the oldest types of dental therapy used to rehabilitate patients with complete or partial edentulousness. The main function of the edentulous alveolar ridge is to provide a major area of support for the dentures.1 Ill-fitting prosthesis leads to a condition where there is no longer adequate support of bone due to RRR. Hence, rehabilitation of such cases pose a clinical challenge, as there is a decreased denture foundation area for support, retention and stability.2 Residual ridge resorption (RRR) is the severe atrophy of alveolar bone underlying the mucoperiosteum. RRR affects the alveolar bone morphology, resulting in a decreased denture foundation area and increased inter-alveolar ridge space. The increase in inter-ridge distance provides a huge restorative space which results in a heavier complete denture due to greater volume of denture base material. This increase in restorative space amalgamates with the long lip length of the patient which gives rise to huge challenge to the success of the complete denture. Also, decreased denture foundation area increases the heaviness of the prosthesis and negatively affects the retention of the denture due to gravity.3 Various weight-reduction techniques have been used in the past using a rigid three-dimensional spacer, such as dental stone (Ackerman, 1955), cellophanewrapped asbestos, silicone putty during laboratory preparation to keep denture base content out of the intended hollow cavity of the prosthesis. The following case report describes a distinct lab technique for construction of hollow maxillary complete denture for a patient with severe RRR.

Single-cell sequencing of the small and AT-skewed genome of malaria parasites

Single-cell genomics is a rapidly advancing field; however, most techniques are designed for mammalian cells. We present a single-cell sequencing pipeline for an intracellular parasite, Plasmodium falciparum, with a small genome of extreme base content. Through optimization of a quasi-linear amplification method, we target the parasite genome over contaminants and generate coverage levels allowing detection of minor genetic variants. This work, as well as efforts that build on these findings, will enable detection of parasite heterogeneity contributing to P. falciparum adaptation. Furthermore, this study provides a framework for optimizing single-cell amplification and variant analysis in challenging genomes.

Jasmonate inhibits adventitious root initiation through transcriptional repression of CKX1 and activation of RAP2.6L transcription factor in Arabidopsis

Adventitious rooting is a de novo organogenesis process that enables plants to propagate clonally and cope with environmental stresses. Adventitious root initiation (ARI) is controlled by interconnected transcriptional and hormonal networks, but there is little knowledge of the genetic and molecular programs orchestrating these networks. Thus, we have applied genome-wide transcriptome profiling to elucidate the profound transcriptional reprogramming events preceding ARI. These reprogramming events are associated with downregulation of cytokinin (CK) signaling and response genes, which could be triggers for ARI. Interestingly, we found that CK free-base content declined during ARI, due to downregulation of de novo CK biosynthesis and upregulation of CK inactivation pathways. We also found that MYC2-dependent jasmonate (JA) signaling inhibits ARI by downregulating expression of the CYTOKININ OXIDASE/DEHYDROGENASE1 gene. We also demonstrated that JA and CK synergistically activate expression of RELATED to APETALA2.6 LIKE (RAP2.6L) transcription factor, and constitutive expression of this transcription factor strongly inhibits ARI. Collectively, our findings reveal that previously unknown genetic interactions between JA and CK play key roles in ARI

The Application of Copper-Gold Catalysts in the Selective Oxidation of Glycerol at Acid and Basic Conditions

The crude glycerol is produced during the transesterification of animal fats and vegetable oils, but it is a by-product of this process. Currently, its elimination is a problem in the chemical industry. The main goal of this work was the preparation, characterization and application of mesoporous cerium-zirconium oxide as supports for copper and gold species and the comparison of selected factors on the properties of catalysts in glycerol oxidation in the liquid phase. The samples were characterized using adsorption and desorption of nitrogen, XRD, UV-vis, XPS, TEM, SEM, and STEM-EDXS. The obtained results of glycerol oxidation show that the bimetallic copper-gold catalysts are more active and selective to glyceric acid in this reaction than analogous monometallic gold catalysts. Additionally, bimetallic catalysts are also characterized by the catalytic stability, and their application leads to the increase of selectivity to glyceric acid during their reusing in glycerol oxidation in alkali media. In this work, the influence of selected factors, e.g., oxygen source and its pressure, solution pH, and base content on the catalytic activity of bimetallic catalysts is discussed.

VARIETY-SPECIFIC FEATURES OF BARLEY AT DIFFERENT STAGES OF ONTOGENESIS

In modern technologies of growing grain crops, high priority is given to the choice of varieties with significant adaptive potential and the development of ways to increase the resistance of plants to the action of various stresses. The purpose of our research was to identify the specific features of different varieties of barley during critical periods of growth. The studies were carried out in 2020–2021. The objects of research were varieties of spring barley created in the Moscow Research Institute of Agriculture. A series of laboratory and vegetative experiments were conducted, in the course of which we studied the indicators of the physiological status and varietal specificity of the resistance of spring barley to oxidative stress induced by an osmotically active sucrose solution during de-etiolation (laboratory experiments) and caused by soil drought at the VI stage of organogenesis (vegetative experiment, varieties ‘Vladimir’ and ‘Raushan’). The biometric indicators of sprouts and indicators of water status were evaluated. In all experiments, the varieties responded to stress by increasing the content of the oxidative stress marker malondialdehyde (MDA). Weak resistance of vegetative organs was noted in 1) roots – variety ‘Raushan’ (3.8 under stress conditions vs. 0.92 μM/g of raw mass under optimal conditions). ‘Moskovsky 2’ (8.1 vs.2.0), ‘Elf’ (4.5 vs. 1.38); 2) sprouts – ‘Raushan’ (4.6 vs.1.54), ‘Elf’ (5.0 vs. 1.37), ‘Nur’ (6.0 vs. 2.4). Varieties ‘Moskovsky 86’ and ‘Vladimir’ were the most resistant to stress since the accumulation of MDA increased to a lesser extent compared to its base content (‘Moskovsky 86’ – sprouts: 5.5 vs. 2.8; roots: 3.0 vs. 2.2 μM/g of raw mass; ‘Vladimir’ – sprouts: 3.4 vs. 2.9; roots: 3.9 vs.3.2 μM/g). Moreover, the content of chlorophylls a, b and carotenoids in varieties ‘Moskovsky 86’ and ‘Vladimir’ decreased respectively by 5.1; 5,9; 6.7 % and 8.0; 17,4; 6.9 % compared to the control options. Thus, variety ‘Vladimir’ is more stress-resistant than the other ones.

THE EFFECTIVENESS OF THE REFUTATION TEXT TO IMPROVE UNDERSTANDING OF THE ACID-BASE CONCEPTS FOR HIGH SCHOOL STUDENTS

Acid-base is a difficult subject to learn. It includes conceptually tricky words for the students. The theme is also considered difficult by teachers and prospective teachers in teaching and assessing student mastery. A misconception in chemistry topics is one of the biggest challenges for the teacher. This means that many students do not reach the learning objective. The acid-base question is considered one of the most challenging subjects, and there are many misunderstood concepts on this topic. Lack of understanding can be reduced by providing a simple and natural source of learning, such as a refutation text. This study aimed to determine the effectiveness of the refutation text to improve understanding of concepts and reduce misunderstanding in corrective learning on the acid-base topic for high school. There are six subtopics on acid-base content for high school. The test method used was the pre and post-project of a group, with a limited number of subjects. The test instrument used was the three-tiers of multiple choices for acid-base material (concept understanding’s test). The analysis result showed that 17 of 19 students had increased knowledge of concepts and decreased misconceptions. The concept change was significant, according to Mc Nemar Test. The value of effect size (ES) based on the Crochan-Q test was 4.12, a high category. It could be concluded that refutation text is effective enough to improve students' concepts and apply them to remedial learning.

A Journey from Improper Gaussian Signaling to Asymmetric Signaling

p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 9.0px Helvetica} <p>The deviation of continuous and discrete complex</p> <p>random variables from the traditional proper and symmetric</p> <p>assumption to a generalized improper and asymmetric characterization</p> <p>(accounting correlation between a random entity</p> <p>and its complex conjugate), respectively, introduces new design</p> <p>freedom and various potential merits. As such, the theory of</p> <p>impropriety has vast applications in medicine, geology, acoustics,</p> <p>optics, image and pattern recognition, computer vision, and</p> <p>other numerous research fields with our main focus on the</p> <p>communication systems. The journey begins from the design of</p> <p>improper Gaussian signaling in the interference-limited communications</p> <p>and leads to a more elaborate and practically</p> <p>feasible asymmetric discrete modulation design. Such asymmetric</p> <p>shaping bridges the gap between theoretically and practically</p> <p>achievable limits with sophisticated transceiver and detection</p> <p>schemes in both coded/uncoded wireless/optical communication</p> <p>systems. Interestingly, introducing asymmetry and adjusting the</p> <p>transmission parameters according to some design criterion</p> <p>render optimal performance without affecting the bandwidth or</p> <p>power requirements of the systems. This dual-flavored article</p> <p>initially presents the tutorial base content covering the interplay</p> <p>of reality/complexity, propriety/impropriety and circularity/noncircularity</p> <p>and then surveys majority of the contributions in this</p> <p>enormous journey.</p>

A Journey from Improper Gaussian Signaling to Asymmetric Signaling

p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 9.0px Helvetica} <p>The deviation of continuous and discrete complex</p> <p>random variables from the traditional proper and symmetric</p> <p>assumption to a generalized improper and asymmetric characterization</p> <p>(accounting correlation between a random entity</p> <p>and its complex conjugate), respectively, introduces new design</p> <p>freedom and various potential merits. As such, the theory of</p> <p>impropriety has vast applications in medicine, geology, acoustics,</p> <p>optics, image and pattern recognition, computer vision, and</p> <p>other numerous research fields with our main focus on the</p> <p>communication systems. The journey begins from the design of</p> <p>improper Gaussian signaling in the interference-limited communications</p> <p>and leads to a more elaborate and practically</p> <p>feasible asymmetric discrete modulation design. Such asymmetric</p> <p>shaping bridges the gap between theoretically and practically</p> <p>achievable limits with sophisticated transceiver and detection</p> <p>schemes in both coded/uncoded wireless/optical communication</p> <p>systems. Interestingly, introducing asymmetry and adjusting the</p> <p>transmission parameters according to some design criterion</p> <p>render optimal performance without affecting the bandwidth or</p> <p>power requirements of the systems. This dual-flavored article</p> <p>initially presents the tutorial base content covering the interplay</p> <p>of reality/complexity, propriety/impropriety and circularity/noncircularity</p> <p>and then surveys majority of the contributions in this</p> <p>enormous journey.</p>