Development of a Parkinson’s disease specific falls questionnaire

Background Falls are a major health burden for older adults with Parkinson’s disease (PD), but there is currently no reliable questionnaire to capture the circumstances and consequences of falls in older adults with PD. This study aimed to develop a PD-specific falls questionnaire and to evaluate its test-retest reliability in older adults with PD. Methods A novel PD-specific falls questionnaire (PDF-Q) was developed in two modes (online and paper-based version) and used to assess falls and near-falls events over the past 12-months. Questions were agreed upon by an expert group, with the domains based on previous falls-related questionnaires. The questions included the number and circumstances (activities, location and direction) of falls and near-falls, and consequences (injuries and medical treatment) of falls. The PDF-Q was distributed to 46 older adults with PD (online n = 30, paper n = 16), who completed the questionnaire twice, 4 weeks apart. Kappa (κ) statistics were used to establish test-retest reliability of the questionnaire items. Results Pooled results from both questionnaires for all participants were used to assess the overall test-retest reliability of the questionnaire. Questions assessing the number of falls (κ = 0.41) and the number of near-falls (κ = 0.51) in the previous 12-months demonstrated weak agreement, while questions on the location of falls (κ = 0.89) and near-falls (κ = 1.0) demonstrated strong to almost perfect agreement. Questions on the number of indoor (κ = 0.86) and outdoor (κ = 0.75) falls demonstrated moderate to strong agreement, though questions related to the number of indoor (κ = 0.47) and outdoor (κ = 0.56) near-falls demonstrated weak agreement. Moderate to strong agreement scores were observed for the most recent fall and near-fall in terms of the direction (indoor fall κ = 0.80; outdoor fall κ = 0.81; near-fall κ = 0.54), activity (indoor fall κ = 0.70; outdoor fall κ = 0.82; near-fall κ = 0.65) and cause (indoor fall κ = 0.75; outdoor fall κ = 0.62; near-fall κ = 0.56). Conclusions The new PDF-Q developed in this study was found to be reliable for capturing the circumstances and consequences of recent falls and near-falls in older adults with PD.

Adaptability to Balance Perturbations During Walking as a Potential Marker of Falls History in Older Adults

Given that falls most commonly occur during walking due to unexpected balance perturbations like trips and slips, walking-based balance assessment including walking stability and adaptability to such perturbations could be beneficial for fall risk assessment in older adults. This cross-sectional study reanalyzed data from two larger studies conducted with the same walking protocol. Participants completed unperturbed walking trials at speeds of 0.4 m/s up to 1.8 m/s in 0.2 m/s steps. Ten unannounced treadmill belt acceleration perturbations were then applied while participants walked at equivalent stability, assessed using the margins of stability. Retrospective (12 months) falls incidence was collected to divide participants into people with and without a history of falls. Twenty older adults (mean age 70.2 ± 2.9 years) were included in this analysis; eight people with one or more recent falls and 12 people without, closely matched by sex, age and height. No significant differences were found in unperturbed walking parameters or their variability. Overall perturbation-recovery step behavior differed slightly (not statistically significant) between the groups after the first perturbation and differences became more pronounced and significant after repetition of perturbations. The No-Falls group significantly reduced the number of recovery steps needed across the trials, whereas the Falls group did not show these improvements. People with a previous fall tended to have slightly delayed and more variable recovery responses after perturbation compared to non-fallers. Non-fallers demonstrate more signs of adaptability to repeated perturbations. Adaptability may give a broader indication of the ability of the locomotor system to respond and improve responses to sudden walking perturbations than unperturbed walking variability or recovery to a single novel perturbation. Adaptability may thus be a more useful marker of falls history in older adults and should be considered in further research.

Demographic Characteristics and Functional Levels of Patients With Fragility Fractures Who Accept Tele-rehabilitation as an Alternative to Face-to-face Home Rehabilitation

There is a gap in the evidence on telerehabilitation (TR) for people with fragility fractures. It is unclear whether this group with recent falls who are often frail with cognitive changes will accept tele-rehabilitation and functional gains can be achieved using this approach. Prospective observational study of consecutive patients admitted with femoral or pelvic fracture to a hospital-based home rehabilitation service (HRS) between January and November 2017. Using tablets, multidisciplinary rehabilitation was provided via videoconferencing and use of exercise apps. Patients chose a face-to-face visit or TR. Information on demographic characteristics, functional levels, the total number of therapy sessions, TR episodes, reasons for non-acceptance of TR, and patient-reported experience using TR was collected. Fifty-two patients with hip and pelvic fractures were admitted to the HRS and 35 (67.3%) received TR. Patients who did not accept TR were older, frailer and more likely to be female than those who received TR. Of the 17 who did not receive TR, 6 were deemed unsuitable by staff due to hearing, vision or cognitive problems and 3 refused. The TR group achieved acceptable functional gains. In the TR group on average, participants had 13.63 (± 7.29) home visits however they only elected to have 3.43 (± 2.48) sessions delivered via TR. TR was acceptable to a subset of hip fracture patients but face-to-face was the preferred mode of delivery. More research is needed to understand patients’ preferences and beliefs, and the influence of clinician attitudes on uptake of TR.

Subjective Hearing Difficulty and Fall Risk

Purpose Hearing loss is a risk factor for falls. The purpose of this study was to investigate the relation between subjective hearing difficulty and risk of falls. Method Community-dwelling older adults, aged 60 years and older, completed a case history; three questionnaires, including the Hearing Handicap Inventory for the Elderly (HHIE), Dizziness Handicap Inventory (DHI), Activities-Specific Balance Confidence Scale (ABC); and one functional balance measure, the Timed Up and Go (TUG) test. Pearson and Spearman correlations were calculated, and average scores were plotted according to group and HHIE score category for DHI, ABC, TUG, the number of medications, and the number of recent falls. Results Seventy-four participants were included in this analysis: 28 nonaudiology patients, 18 audiology patients with hearing aids, and 28 audiology patients without hearing aids. Significant positive correlations were noted between HHIE and DHI scores for audiology patients without hearing aids and between HHIE score and number of recent falls for audiology patients with hearing aids. When average scores were plotted for DHI, ABC, TUG, the number of medications, and the number of recent falls according to group and category, there were clear trends toward increased fall risk as HHIE score categories increased (i.e., mild to moderate to severe) based on previously used criteria. Conclusions Overall, a trend was noticed such that, for increasing HHIE score categories, fall risk increased. Significant correlations existed between HHIE score and some of the measures used to indicate fall risk (i.e., DHI score, number of recent falls). Future fall risk research should investigate subjective hearing difficulty as a risk factor, as well as pure-tone audiometric thresholds.

Fall Characteristics Among Elderly Populations in Urban and Rural Areas in Korea

BackgroundFalling is one of the leading causes of injury among elderly populations. As the population over 65 years old increases, medical costs due to falling will also increase. Urban and rural areas have different fall characteristics, and research into these differences is lacking.MethodsA survey was conducted on 2,012 people over 60 years old between September 1, 2015 to October 12, 2015. Guro-gu (Seoul), Yeongdeungpo-gu (Seoul), and Jung-gu (Daegu) were classified as urban areas and included 1,205 of the study participants. Dalseong-gun (Daegu) and Yangpyeong-gun (Gyeonggi-do) were categorized as rural areas and included 807 participants. Several region characteristics, including population density, were considered to distinguish between urban and rural areas. The survey included questions about fall history, cause, season and time of recent falls, and external conditions associated with recent falls, like floor or ground material and shoe types.ResultsRural respondents were older than urban respondents (p<0.001) but did not differ significantly in gender proportion (p=0.082). Fall history over the past year was not different between the two regions (p=0.693), but lifetime fall history was greater among rural respondents (p<0.001). Only 5.1% of all respondents had undergone fall-prevention education. A slippery floor was the most common cause of falls in both regions, but there was a significant difference in pattern of fall causes (p<0.001). Falls were more frequent in the summer, spring, and the afternoon in urban areas, and in the summer, autumn, and the morning in rural areas. Cement and asphalt were the most common ground materials at the time of falls in both regions, but rural respondents had higher fall rates when walking on soil and when wearing slippers.ConclusionsA fall-prevention program that reflects the characteristics and differences of falls in urban and rural areas should be developed and used to effectively prevent falling among elderly people.

Abnormal center of mass control during balance is associated with falls in Parkinson’s disease

Although Parkinson disease (PD) causes profound balance impairments, we know very little about how PD impacts the sensorimotor networks we rely on for automatically maintaining balance control. In young healthy people and animals, muscles are activated in a precise temporal and spatial organization when the center of body mass (CoM) is unexpectedly moved. This organization is largely automatic and determined by feedback of CoM motion. Here, we show that PD alters the sensitivity of the sensorimotor feedback transformation. Importantly, sensorimotor feedback transformations for balance in PD remain temporally precise, but become spatially diffuse by recruiting additional muscle activity in antagonist muscles during balance responses. The abnormal antagonist muscle activity remains precisely time-locked to sensorimotor feedback signals encoding undesirable motion of the body in space. Further, among people with PD, the sensitivity of abnormal antagonist muscle activity to CoM motion varies directly with the number of recent falls. Our work shows that in people with PD, sensorimotor feedback transformations for balance are intact but disinhibited in antagonist muscles, likely contributing to balance deficits and falls.

Patterns of Home Environmental Modification Use and Functional Health: The Women’s Health Initiative

Background We examined common patterns of home environmental modification (HEM) use and associated major (including disability-, cardiovascular-, and cancer-related) health conditions and events among older women. Methods Women, aged 78.6 ± 6.3 years (n = 71,257), self-reported utilization of nine types of HEMs (hand rails, grab bars, ramps, nonslip surfaces, tacking carpets/rugs, decreasing clutter, increasing lighting, raised sink/counter heights, other). Concurrent history of major health conditions and events was collected. Odds ratios (ORs) were estimated based on overall HEM use and four latent classes (low HEM use [56%], rails/grab bars [20%], lighting/decluttering [18%], high HEM use [5%]), adjusted for age, marital status, race/ethnicity, education, depression, and obesity. Results Fifty-five percent of women reported using any HEM (overall), with strongest associations among disability-related conditions. Activities of daily living limitations were strongly associated with high HEM use (OR = 8.16, 95% confidence interval [CI] = 6.62–10.05), railing/grab bar use (OR = 4.02, 95% CI = 3.26–4.95), and lighting/declutter use (OR = 1.87, 95% CI = 1.40–2.50) versus low HEM use. Recent falls were positively associated with overall HEM use (OR = 1.79, 95% CI = 1.72–1.87); high HEM use (OR = 2.89, 95% CI = 2.64–3.16), railings/grab bars use (OR = 2.32, 95% CI = 2.18–2.48), and lighting/declutter use (OR = 1.93, 95% CI = 1.79–2.08) were positively associated with recent falls. Modest associations were observed between HEM use and select (ie, atrial fibrillation, heart valve disease, stroke) cardiovascular outcomes. Conclusions Among older women, disability-related conditions, including functional limitations and recent falls, were strongly associated with overall HEM use, high HEM use, and railings/grab bar use.

73 Exercise Habit is Associated with Lower Fall Risks among Elderly People Living in Urban Areas

In the present super aged society that has limited financial resources for efficient health care for the elderly population, fall prevention is an urgent issue. The present study examined the relationship between exercise habit and fall risks among elderly people living in an urban area. A total of 1,014 elderly people (age: 65–89 years) living in Osaka City were enrolled in this study and assigned to 5 different age groups. The motor abilities of the participants were evaluated by the Functional Reach Test (FRT) and the Timed Up and Go (TUG) test, with the cutoff value for fall risk set at 25 cm and 13.5 s, respectively. Exercise habit (≤1 h, 1–2 h, or ≥2 h per week), history of recent falls, and anxiety about falling were also assessed using a questionnaire modified from the checklist by the Ministry of Health, Labour and Welfare of Japan. The results of the FRT and TUG tests were increasingly poorer in higher age groups. History of recent falls and anxiety about falling were also more frequent in higher age groups (all p &lt; .05). The prevalence of exercise habits was similar among the age groups. In the age groups &gt;75 years, there was an association between exercise habit and a decrease in fall risks, based on the FRT results (all p &lt; .05). The mean FRT value of the participants with the greatest exercise habit was equivalent to that of the generation 10 years younger with the lowest exercise habit. There was an association between exercise habit and decreased anxiety about falling (p = .003), but not with a history of recent falls. Our results suggest that exercise should be promoted among elderly people living in urban areas to contribute to fall prevention.