This chapter describes the work of SisterLove, an Atlanta-based organization that takes an avowedly intersectional approach to fighting AIDS among Black women, also turned its attention to AIDS in Africa during the 1990s. Dázon Dixon Diallo, the founder and CEO of SisterLove, got her start in women’s health as a student at Spelman College, where she became involved in the abortion rights movement as well as in the Black women’s health movement. Those early experiences would shape her approach to AIDS education through SisterLove, where she took care to include all kinds of Black women in the group’s outreach, at times focusing specifically on rural women, recently incarcerated women, and women in public housing. Dixon Diallo and SisterLove started from the notion that AIDS programs for African American women needed to address the ways that their lives were shaped by the simultaneous interlocking oppressions of racism and sexism. As the group expanded into South Africa, it also considered the ways that other axes of power, including those of class, region, and nation, shaped Black women’s experiences with AIDS and thus should shape SisterLove’s work as well.