Global processing provides malignancy evidence complementary to the information captured by humans or machines following detailed mammogram inspection

The information captured by the gist signal, which refers to radiologists’ first impression arising from an initial global image processing, is poorly understood. We examined whether the gist signal can provide complementary information to data captured by radiologists (experiment 1), or computer algorithms (experiment 2) based on detailed mammogram inspection. In the first experiment, 19 radiologists assessed a case set twice, once based on a half-second image presentation (i.e., gist signal) and once in the usual viewing condition. Their performances in two viewing conditions were compared using repeated measure correlation (rm-corr). The cancer cases (19 cases × 19 readers) exhibited non-significant trend with rm-corr = 0.012 (p = 0.82, CI: −0.09, 0.12). For normal cases (41 cases × 19 readers), a weak correlation of rm-corr = 0.238 (p < 0.001, CI: 0.17, 0.30) was found. In the second experiment, we combined the abnormality score from a state-of-the-art deep learning-based tool (DL) with the radiological gist signal using a support vector machine (SVM). To obtain the gist signal, 53 radiologists assessed images based on half-second image presentation. The SVM performance for each radiologist and an average reader, whose gist responses were the mean abnormality scores given by all 53 readers to each image was assessed using leave-one-out cross-validation. For the average reader, the AUC for gist, DL, and the SVM, were 0.76 (CI: 0.62–0.86), 0.79 (CI: 0.63–0.89), and 0.88 (CI: 0.79–0.94). For all readers with a gist AUC significantly better than chance-level, the SVM outperformed DL. The gist signal provided malignancy evidence with no or weak associations with the information captured by humans in normal radiologic reporting, which involves detailed mammogram inspection. Adding gist signal to a state-of-the-art deep learning-based tool improved its performance for the breast cancer detection.

Effective image visualization for publications – a workflow using open access tools and concepts

Today, 25% of figures in biomedical publications contain images of various types, e.g. photos, light or electron microscopy images, x-rays, or even sketches or drawings. Despite being widely used, published images may be ineffective or illegible since details are not visible, information is missing or they have been inappropriately processed. The vast majority of such imperfect images can be attributed to the lack of experience of the authors as undergraduate and graduate curricula lack courses on image acquisition, ethical processing, and visualization. Here we present a step-by-step image processing workflow for effective and ethical image presentation. The workflow is aimed to allow novice users with little or no prior experience in image processing to implement the essential steps towards publishing images. The workflow is based on the open source software Fiji, but its principles can be applied with other software packages. All image processing steps discussed here, and complementary suggestions for image presentation, are shown in an accessible “cheat sheet”-style format, enabling wide distribution, use, and adoption to more specific needs.

Dialogue between cultures: FL textbook as a foundation for high-quality education

High-quality education is one of the main goals of Russia today. To reach it, the educational authorities, textbook and study guides authors and teachers should cooperate to identify the main problems and find their solution. One of the serious challenges of the Russian students is poor knowledge of foreign languages that reduces their chances to continue their education abroad. One of the ways to improve knowledge of a foreign language is to provide motivational and up-to-date educational resources including textbooks and visual aids. This research analyzes ESL textbooks from the point of view of Russia’s image presentation. Several cognitive strategies of the country’s image presentation have been singled out, among the most frequent are inclusion of phenomena of Russian culture along with culture-bound information of other countries; stereotypical representation of Russian culture without modern socio-cultural context; emphasis on Russian scientific achievements; presentation of traditional and historic facts; and emphasis on Russian politics. Students’ attitudes to culture bound materials are revealed in a survey. Recommendations to textbook authors and teachers are provided.