The importance of political parties has been at the heart of the debate about regime and regime change. Parties are essential actors for democratic politics. They can trigger transitions from and to democracy, polarize making democracies vulnerable to breakdown, or manage conflict to protect democratic institutions. However, not all parties or party systems are equal. The levels of fragmentation, polarization, and institutionalization in any given party and/or party system are key to understanding the rise, fall, and survival of democracy. In Latin America, the literature has focused, mostly, on party and party system institutionalization. In general, scholars agree that institutionalization fosters democracy. The organizational strength and embeddedness of political parties in society and the extent to which they interact regularly in stable ways, they argue, is key to the survival of democratic politics. There are instances, however, that suggest that this relationship is more problematic than the literature assumes. In contexts of crisis, highly institutionalized parties and party systems can be slow to adjust to new groups or demands and stiffen party leaders’ ability to respond to new issues. When facing a polarizing potential autocrat, for instance, high levels of party and party system institutionalization could hurt more than help democracy. They can reduce the ability of politicians to attract moderate voters from opposing parties, hinder their capacity to counteract antisystemic trends in order to lead opposition efforts, or limit the extent to which they can reach across the aisle to build ideologically diverse prodemocratic coalitions.