Nanostructured Lipid Carriers-Hydrogels System for Drug Delivery: Nanohybrid Technology Perspective

Advanced hybrid component development in nanotechnology provides superior functionality in the application of scientific knowledge for the drug delivery industry. The purpose of this paper is to review important nanohybrid perspectives in drug delivery between nanostructured lipid carriers (NLC) and hydrogel systems. The hybrid system may result in the enhancement of each component’s synergistic properties in the mechanical strength of the hydrogel and concomitantly decrease aggregation of the NLC. The significant progress in nanostructured lipid carriers–hydrogels is reviewed here, with an emphasis on their preparation, potential applications, advantages, and underlying issues associated with these exciting materials.

How do Positive Deviants Overcome Health-Related Stigma? An Exploration of Development of Positive Deviance Among People With Stigmatized Health Conditions in Indonesia

A constructivist grounded theory approach was used to understand how some people living with stigmatized health conditions develop positive deviance to overcome stigma. We examined interviews from 13 identified positive deviants living with four different stigmatized health conditions (HIV, leprosy, schizophrenia, and diabetes) in Indonesia. Positive deviance develops in the form of psychological empowerment through improvement of self-belief and perception (intrapersonal component), development of understanding and skill to exert control in life (interactional component), and self-discovery of successful behaviors and strategies to avert stigma (behavioral component). Positive deviants, after being empowered, start empowering others affected by sharing their knowledge and fostering social awareness and acceptance. The findings revealed the presence of problem-solving ability and agency within the community of stigmatized individuals in Indonesia and warrant researchers to partner with the community to expedite the diffusion of transferable positive deviant strategies within and outside the communities.

study of older preschool children’s sensitivity formation state

The purpose of the study is to diagnose the state of older preschool children’s sensitivity formation. The object is the process of older preschool children’s moral education. The study used a set of the following research methods: an analysis, a synthesis, a comparison, a generalization of scientific sources in order to formulate basic concepts and study the level of the issue concern; an observation of children’s play activities; a conversation; a plot role-playing games ‘Hospital’ and ‘Veterinary Clinic,’ a didactic game ‘Who is sensitive?’; methods of mathematical statistics for processing the obtained experimental data. Analysis of the experimental study results allowed us to state the lack of older preschool children’s awareness with the category ‘sensitivity’ and its emotional and activity display. The vast majority of preschoolers understand the theoretical meaning of this category, however, they do not realize the need to be sensitive, can not explain the motives of their sensitive behavior, and are not able to name the sensitive actions of other people. Only a small number of children associate sensitive actions with care, protection, and help. We have noted the highest rate of the emotional and value component development because children tend to show moral feelings.

Analisis technology contribution coefficient (TCC) di UKM Gazal Makmur

Technology is an important aspect for the success of an industry. Gazal Makmur UKM is an UKM that processes cassava into chips in Gazal Hamlet, Kotaanyar Village, Kotaanyar District, Probolinggo Regency. This study aims to calculate the value of the technology component contribution coefficient (TCC) and determine the priority of technology component development in Gazal Makmur SMEs. The method used in this study is the technometric method, namely the technology assessment method used to evaluate the contribution of technology components and the pairwise comparison matrix approach. The measured technology components include technoware (production equipment), humanware (human resource capabilities), infoware (information tools), and orgaware (organizational tools). The results of this study indicate that the contribution of the Orgaware component is the highest in Gazal Makmur SMEs (0.578), then humanware (0.467), humanware (0.252), and the smallest is technoware (0.0.244). The TCC value for Gazal Makmur SMEs is 0.418. The results of this calculation show that these SMEs have a TCC value below 0.7 and above 0.3, meaning that it can be concluded that these SMEs are classified as having a semi-modern level of technology with a reasonable technology category for the SME scale. Improving the quality of Gazal Makmur cassava chips SMEs starts from the orgaware component then humanware, infoware and finally orgaware.