Penerapan Kompres Jahe Untuk Mengurangi Nyeri Pada Lansia Penderita Asam Urat

Gout is a disease that attacks the joint area, caused by consuming too many foods with high purine content, and sufferers feel pain and swelling in the joints. One ofthe ways to reduce pain by compressing with ginger. This study aims to apply the way in order to reduce on the elderly with gout. The result stated both have decreased pain scale. The first patients has decreased the scalen from 5 to 2, and the latter had decreased the scale from 4 to 2, Furthermore, the patients and the family finally have understood the treatment of gout. Therefore, it can be concluded that compressing theraphy with ginger can reduce pain in the joints of eldery patients with gout. Thus, it is expected for the nursing staff to teach the theraphy on the patient and the familyKeywords : gout; compressing with ginger; elderly AbstrakAsam urat merupakan penyakit yang menyerang pada area sendi yang disebabkan banyaknya mengonsumsi makanan dengan kandungan purin tinggi dengan keluhan nyeri dan bengkak pada sendi. Tindakan untuk mengurangi nyeri salah satunya adalah kompres jahe. Tujuan dari studi kasus ini adalah menerapkan kompres jahe untuk mengurangi nyeri pada lansia penderita asam urat.Metode yang digunakan adalah metode deskriptif, yaitu metode yang digunakan untuk menganalisis data dengan cara mendeskripsikan atau menggambarkan data yang telah terkumpul. Hasil studi kasus ini pasien I dan II terjadi penurunan skala nyeri pasien I dari skala 5 menjadi 2 dan pasien II dari skala 4 menjadi 2, serta memahami perawatan pada asam urat. Kesimpulan studi kasus ini bahwa terapi kompres jahe dapat menurunkan nyeri pada persendian pasien lansia penderita asam urat. Saran untuk perawat diharapkan mengajarkan cara mengatasi penyakit asam urat dengan menggunakan terapi kompres jahe.Kata kunci : Asam urat;, kompres jahe; lansia

The transcriptional elongation rate regulates alternative polyadenylation in yeast

Yeast cells undergoing the diauxic response show a striking upstream shift in poly(A) site utilization, with increased use of ORF-proximal poly(A) sites resulting in shorter 3’ mRNA isoforms for most genes. This altered poly(A) pattern is extremely similar to that observed in cells containing Pol II derivatives with slow elongation rates. Conversely, cells containing derivatives with fast elongation rates show a subtle downstream shift in poly(A) sites. Polyadenylation patterns of many genes are sensitive to both fast and slow elongation rates, and a global shift of poly(A) utilization is strongly linked to increased purine content of sequences flanking poly(A) sites. Pol II processivity is impaired in diauxic cells, but strains with reduced processivity and normal Pol II elongation rates have normal polyadenylation profiles. Thus, Pol II elongation speed is important for poly(A) site selection and for regulating poly(A) patterns in response to environmental conditions.

The Factors Affecting The Incidence Of Hyperuricemia On The Rejang Tribe In Bengkulu

The Rejang tribe is partly living on the lowland and coastal coastline, the typical Rejang cooking tradition has been assimilated into the Minang and Malay cooking traditions. Malay people like to consume foods that are fatty, dining, oily and salty. Fish, beef, shrimp and nuts have purine content of 9-100 mg of purin/100 g of foodstuffs. One of the factors affecting hyperuricemia is the habit of consuming purine eating, it will result in gout disease. The purpose of this research is to determine the factors that influence the incidence of hyperuricemia on the Rejang tribe in Bengkulu. Design research is cross sectional. Rejang Group's research samples numbered 64 respondents. Data collected is the result of uric acid examination, gender, age, knowledge, consumption pattern, liquid consumption, BMI. The instruments used are questionnaires, eating consumption patterns using FFQ form, weight gained by weighing with digital scales. Data analysis using Chi-Square and multivariate tests using logistic regression test

Purine and uric acid contents of common edible insects in Southwest China

Edible insects have recently been considered as a potential food source that may solve problems of malnutrition and starvation worldwide. However, studies exploring insects as food sources are mainly focused on entomophagy and nutrition rather than the potential risks of excessive metabolite contents, such as purine and uric acid. In this study, we analysed guanine, hypoxanthine, xanthine, adenine and uric acid concentrations in 11 species of edible insects from Yunnan and Guizhou provinces in Southwest China, including 5 species of dragonfly, 3 species of wasp and a single species of locust, mealworm and silkworm. Purine and uric acid contents differed distinctly between these insects, and guanine and xanthine were the dominant purines in all samples. The proportions of 4 purines in the total purine content of these insects differed markedly from those in meat samples from poultry and livestock, and uric acid contents varied significantly between aquatic insects and terricolous insects, such as silkworm pupa. Taken together, the present data show that most edible insects are potent food sources of purine.