Influence of Cryogenic Treatment and Thermal Shock on Quenching Stresses and Properties of Alloy D16

This paper presents the results of heat treatment influence, including quenching in water, cooling of the alloy in liquid nitrogen, holding in it and thermal shock (heating in hot mineral oil) and also natural or artificial aging on the properties of wrought aluminum alloy D16 (2024). With the help of the hole-drilling strain-gage method the influence of heat treatment on residual stresses was determined and using tensile and indentation tests – specific elongation, reduction of area, yield strength, tensile strength and cracking resistance of alloy D16 (2024) were determined. Corrosion properties were studied with potentiodynamic method in 3% aqueous NaCl solution

Investigation of Plastic Properties of Ø8 Rod Made of Fire-Refined Copper of Kmor Grade

Results of the comparative ductility evaluation of Ø8 rods made of copper of the KM and KMor grades are discussed. It has been found out that plastic properties of KM and KMor grade rods at room temperature practically do not differ in their specific elongation and after-fracture contraction indices. At the same time, the ductility indices of KMor rod at temperature +850 °С became, practically, half-values. Increased spread of physical property values particularly the specific ohmic resistance of the rod KMor can be explained by the cumulative effect of variations of the chemical metal composition, and changes in process variables of the process (for example, unstable density of a cast bar), that initiate an occurrence of tension stresses during rolling. Calculation data of the limiting drawing ratio μr demonstrated that its value must not exceed 1.475.

Influence of thermal strengthening technology on variability of mechanical properties of rolled metal product

Rebars and coiled bar have a tendency to softening over time. After holding at the room temperature the ductility of the rolled products can be partially restored due to the processes of return and relaxation and also deposition of the diffusion-movable hydrogen from the steel. The reverse hydrogen brittleness and ageing are often observed, during production of the thermally strengthening rolled products. The variability of the mechanical properties of rebars and coiled bar of 25G2S, С70D and С82D steels with different diameters has been studied. It has been shown that tendency to softening is decreases during increasing of the strength class of the rebars (steel 25G2S) and it is related to deposition of the hydrogen in different quantities. Dynamics of increase of specific elongation for rebars turns out to be maximum in the first 30 days and growing rapidly (till 4,0…4,5 % abs.) over 90...120 days, then stabilizes and practically does not change over time. After use of the accelerated cooling at the final stage of the deformation heat treatment of the coiled bar of С70D high carbon steel the variability of specific elongation and reduction of area are characterized by a significant increase of ductility indexes within 3 days after primary testing. By research of variability of mechanical properties of coiled bar of С82D steel was established that during initial testing of samples (immediately after rolling) were recorded a low values of specific elongation and reduction of area (7,6…8,4 % and 15…24 % respectively) and while the progress of embrittlement have a tends to growth with increasing diameter. After holding of the coiled bar within 48...72 hours the parameters of the ductility for all diameters of rolled products are grow to 30...34% and stabilize over time. It has been shown that variability of the mechanical properties have a direct relations with the parameters of the structure, the initial hydrogen content in the steel and with degree of deformation processing of blank continuous casting.

Interkinetic nuclear movements promote apical expansion in pseudostratified epithelia at the expense of apicobasal elongation

Pseudostratified epithelia (PSE) are a common type of columnar epithelia found in a wealth of embryonic and adult tissues such as ectodermal placodes, the trachea, the ureter, the gut and the neuroepithelium. PSE are characterized by the choreographed displacement of cells’ nuclei along the apicobasal axis according to phases of their cell cycle. Such movements, called interkinetic movements (INM) have been proposed to influence tissue expansion and shape and suggested as culprit in several congenital diseases such as CAKUT and esophageal atresia. INM rely on cytoskeleton dynamics just as adhesion, contractility and mitosis do. Therefore, longer term impairment of INM without affecting proliferation and adhesion is currently technically unachievable. Here we bypassed this hurdle by generating a 2D agent-based model of a proliferating PSE and compared its output to the growth of the chick neuroepithelium to assess the interplay between INM and these other important cell processes during growth of a PSE. We found that INM directly generates apical expansion and apical nuclear crowding. In addition, our data strongly suggest that apicobasal elongation of cells is not an emerging property of a proliferative PSE but rather requires a specific elongation program. We then discuss how such program might functionally link INM, tissue growth and differentiation.Authors SummaryPseudostratified epithelia (PSE) are a common type of epithelia characterized by the choreographed displacement of cells’ nuclei along the apicobasal axis during proliferation. These so-called interkinetic movements (INM) were proposed to influence tissue expansion and suggested as culprit in several congenital diseases. INM rely on cytoskeleton dynamics. Therefore, longer term impairment of INM without affecting proliferation and adhesion is currently technically unachievable. We bypassed this hurdle by generating a mathematical model of PSE and compared it to the growth of an epithelium of reference. Our data show that INM drive expansion of the apical domain of the epithelium and suggest that apicobasal elongation of cells is not an emerging property of a proliferative PSE but might rather requires a specific elongation program.

Understanding biases in ribosome profiling experiments reveals signatures of translation dynamics in yeast

Ribosome profiling produces snapshots of the locations of actively translating ribosomes on messenger RNAs. These snapshots can be used to make inferences about translation dynamics. Recent ribosome profiling studies in yeast, however, have reached contradictory conclusions regarding the average translation rate of each codon. Some experiments have used cycloheximide (CHX) to stabilize ribosomes before measuring their positions, and these studies all counterintuitively report a weak negative correlation between the translation rate of a codon and the abundance of its cognate tRNA. In contrast, some experiments performed without CHX report strong positive correlations. To explain this contradiction, we identify unexpected patterns in ribosome density downstream of each type of codon in experiments that use CHX. These patterns are evidence that elongation continues to occur in the presence of CHX but with dramatically altered codon-specific elongation rates. The measured positions of ribosomes in these experiments therefore do not reflect the amounts of time ribosomes spend at each position in vivo. These results suggest that conclusions from experiments in yeast using CHX may need reexamination. In particular, we show that in all such experiments, codons decoded by less abundant tRNAs were in fact being translated more slowly before the addition of CHX disrupted these dynamics.