Rare Metachronous Multiple Carcinoma of Ear, Nose and Throat: A Case Report: Metachronous Multiple Carcinoma of Bilateral Maxillary Sinus and Lung

BackegroundTo report a rare case of metachronous multiple carcinoma of bilateral maxillary sinus and lung.MethodsThe clinical manifestations, pathological results, endoscopic findings and imaging features of the patient were collected and summarized.ResultsThe patient, male, 58 years old, came to our department in 2010 for "left exophthalmos and blood in snot". Combined with relevant examinations, it was diagnosed as malignant tumor of the left maxillary sinus. Postoperative radiotherapy and chemotherapy were performed. Ten years later, the patient developed right maxillary sinus cancer and left lung cancer. The postoperative pathological return of lung was lung adenocarcinoma,excluding the possibility of metastasis.ConclusionsFor otorhinolaryngology,this case of isochronous multiple lung cancer in bilateral maxillary sinuses is very rare, which also suggests that we should closely follow up tumor patients in clinical treatment.In addition to the primary site, we should also strengthen the monitoring of radiotherapy operation area and easily metastatic organs (such as lung, bone, liver, etc.), strengthening the popularization of relevant knowledge and improve patients' awareness of disease prevention, changing the bad lifestyle, further reducing the incidence of multiple primary cancer or early detection of cancer and improving the quality of life of patients.

Multiple Carcinoma injuries of squamous cells and Queratoacantoma on vitiligo patient

Vitiligo patients undergo a destruction of melanocytes. The melanin reduction inflicts as a risk factor for the development of skin neoplasia. Cases of malignant nonmelanocytic tumors and melanoma within the vitiligo patients is rare and isolated. This study reports the multiple injuries of the squamous cell carcinoma and keratoacanthoma within the intense vitiligo affected areas.