Factors Associated With Changes In Bone-Mass Density In Post Menopause Female Patients With Osteopenia

Background: Many factors can cause changes in bone mass density (BMD) in women with postmenopausal osteopenia. Aim: Determine factors associated with changes in BMD in postmenopausal women with osteopenia with the most influential risk factors within 1 year. Methods: Survey was conducted on 38 patients who were included in the inclusion criteria with a cross-sectional study analysis and had BMD data for the last 2 years, body mass index, and conducted interviews for physical activity, age of menopause, and duration of menopause. Blood samples were also taken to check total calcium levels, vitamin D levels and estrogen levels. Finally, patients are followed for up to 1 week for daily nutrition records. The relationship between these factors and changes in BMD was analyzed using Pearson's or Spearman's test. The analysis result was considered significant if p<0.05. Results: There was no significant relationship between body mass index, menopause duration, physical activity, dietary calcium, serum calcium levels and serum estradiol levels on changes in BMD with p value > 0.05. However, there was a significant relationship between menopause onset and changes in ward mass density (r = 0,321, p = 0,04) and lumbal 1 (r = 0,333, p = 0,04), serum vitamin D levels and changes in great trochanter mass density (r = 0,336, p = 0,036), physical activity score and changes in ward mass density (r = -0,522, p < 0,01). Conclusion: menopause onset, vitamin D and physical activity are significantly associated with changes in BMD in female patients with postmenopausal osteopenia.

Effect of 12-Month Resistance Training on Quality of Life in Postmenopausal Women with Osteopenia or Osteoporosis: a Pilot Study

The impact of a resistance training program on improving the quality of life is not well established. The present study aimed to evaluate the effects of 12-month resistance training in quality of life in women with postmenopausal osteoporosis or osteopenia. Ten women with postmenopausal osteopenia/osteoporosis were divided into a exercise group and control group. The training program included exercises for upper and lower limb muscles with intensities of 50 –70% of 1RM over a period of 12 months. The quality of life was evaluated before and at the end of the study using the Quality of life questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41). A significant improvement was noted in the quality of life in four of the seven parameters for exercise group compared to control group: pain, social activities, general health and mental function. Resistance training program for women with postmenopausal osteopenia/osteoporosis provides quality of life improvement.