transgenic flax
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Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 767
Author(s):  
Kamar Hamade ◽  
Ophélie Fliniaux ◽  
Jean-Xavier Fontaine ◽  
Roland Molinié ◽  
Elvis Otogo Nnang ◽  
...  

Lignans, phenolic plant secondary metabolites, are derived from the phenylpropanoid biosynthetic pathway. Although, being investigated for their health benefits in terms of antioxidant, antitumor, anti-inflammatory and antiviral properties, the role of these molecules in plants remains incompletely elucidated; a potential role in stress response mechanisms has been, however, proposed. In this study, a non-targeted metabolomic analysis of the roots, stems, and leaves of wild-type and PLR1-RNAi transgenic flax, devoid of (+) secoisolariciresinol diglucoside ((+) SDG)—the main flaxseed lignan, was performed using 1H-NMR and LC-MS, in order to obtain further insight into the involvement of lignan in the response of plant to osmotic stress. Results showed that wild-type and lignan-deficient flax plants have different metabolic responses after being exposed to osmotic stress conditions, but they both showed the capacity to induce an adaptive response to osmotic stress. These findings suggest the indirect involvement of lignans in osmotic stress response.



2019 ◽  
Vol 28 (4) ◽  
pp. 431-438
Author(s):  
Kazimierz Gąsiorowski ◽  
Tomasz Gębarowski ◽  
Helena Moreira ◽  
Anna Kulma ◽  
Michał Szatkowski ◽  
...  
Keyword(s):  




2017 ◽  
Vol 55 ◽  
pp. 187-198 ◽  
Author(s):  
Wioleta Wojtasik ◽  
Magdalena Czemplik ◽  
Marta Preisner ◽  
Lucyna Dymińska ◽  
Guo Yuan ◽  
...  


2016 ◽  
Vol 231 ◽  
pp. S74
Author(s):  
Magdalena Wróbel-Kwiatkowska ◽  
Kamil Kostyn ◽  
Lucyna Dyminska ◽  
Jerzy Hanuza ◽  
Jan Szopa ◽  
...  




2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Katarzyna Skorkowska-Telichowska ◽  
Karolina Hasiewicz-Derkacz ◽  
Tomasz Gębarowski ◽  
Anna Kulma ◽  
Helena Moreira ◽  
...  

Polyunsaturated fatty acids, sterols, and hydrophilic phenolic compounds are components of flax oil that act as antioxidants. We investigated the impact of flax oil from transgenic flax in the form of emulsions on stressed Chinese hamster pulmonary fibroblasts. We found that the emulsions protect V79 cells against the H2O2and the effect is dose dependent. They reduced the level of intracellular reactive oxygen species and protected genomic DNA against damage. The rate of cell proliferation increased upon treatment with the emulsions at a low concentration, while at a high concentration it decreased significantly, accompanied by increased frequency of apoptotic cell death. Expression analysis of selected genes revealed the upregulatory impact of the emulsions on the histones, acetylases, and deacetylases. Expression of apoptotic, proinflammatory, and anti-inflammatory genes was also altered. It is thus suggested that flax oil emulsions might be useful as a basis for biomedical products that actively protect cells against inflammation and degeneration. The beneficial effect on fibroblast resistance to oxidative damage was superior in the emulsion made of oil from transgenic plants which was correlated with the quantity of antioxidants and squalene. The emulsions from transgenic flax are promising candidates for skin protection against oxidative damage.



2015 ◽  
Vol 14 ◽  
pp. 299-307 ◽  
Author(s):  
Magdalena Matusiewicz ◽  
Iwona Kosieradzka ◽  
Małgorzata Sobczak-Filipiak ◽  
Magdalena Zuk ◽  
Jan Szopa


2014 ◽  
Vol 45 (6) ◽  
pp. 337-341 ◽  
Author(s):  
V. A. Lemesh ◽  
T. E. Samatadze ◽  
E. V. Guzenko ◽  
E. V. Zheleznyakova ◽  
A. V. Amosova ◽  
...  
Keyword(s):  


2014 ◽  
Vol 34 (4) ◽  
pp. 1917-1932 ◽  
Author(s):  
Justyna Mierziak ◽  
Wioleta Wojtasik ◽  
Kamil Kostyn ◽  
Tadeusz Czuj ◽  
Jan Szopa ◽  
...  


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