scholarly journals Difference In The Lower Blood Pressure Of Primary Hypertension Patients Participating In Prolanis And Non Prolanis In The Cipayung District Health Center

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Alviani Latifah Fuat ◽  
Fajar Susanti ◽  
Erlin Ifadah
Keyword(s):  
Blood Pressure ◽  
Health Center ◽  
Blood Pressure Reduction ◽  
Primary Hypertension ◽  
Pressure Reduction ◽  
District Health ◽  
Comparison Research ◽  
Study Population ◽  
The Difference ◽  
The Government

Changes in human development at this time greatly affect lifestyles it is a cause of an increase in non- communicable diseases (PTM) one of which is hypertension. Hypertension control has been pursued by the government by implementing a chronic disease prevention program (PROLANIS) through collaboration with BPJS. This study aims to determine the difference in blood pressure reduction in primary hypertension patients who follow prolanis and non prolanis in the Cipayung District Health Center. Pre-experimental research design with static group comparison research. The study population was primary hypertension patients who followed prolanis and non prolanis in the Cipayung District Health Center. Samples were taken by purposive sampling and found 40 people. The collected data is tested statistically by T-test. The results of the study of primary hypertension patients who follow Prolanis have better blood pressure. Statistical test results showed there were differences in blood pressure reduction in primary hypertension patients who followed prolanis and non prolanis (p = 0,000, p <0.05). Nurses provide education to primary hypertension patients who have not yet joined the program to participate in the PROLANIS program.Keyword: Hypertension, Blood Pressure, PROLANIS

A prospective comparative study to examine the effects of oral diazepam on blood pressure and anxiety levels in patients with acute epistaxis

2006 ◽  
Vol 121 (2) ◽  
pp. 124-129 ◽  
Author(s):  
J F Thong ◽  
S Lo ◽  
R Houghton ◽  
V Moore-Gillon
Keyword(s):  
Blood Pressure ◽  
Comparative Study ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Reduction ◽  
Pressure Reduction ◽  
Elevated Blood ◽  
Prospective Comparative Study ◽  
The Difference ◽  
Oral Diazepam

Objective: To examine the effects of oral diazepam on blood pressure and anxiety in patients with acute epistaxis.Study design and setting: A prospective comparative study in an otorhinolaryngology tertiary referral centre.Participants: Patients with acute epistaxis requiring hospital admission.Intervention: Oral diazepam.Main outcome measures: Anxiety and blood pressure levels.Results: 32 patients received diazepam and 45 did not (control). On average, patients were hypertensive on admission (mean [standard deviation (SD)] systolic blood pressure diazepam group=157 mmHg [26], control=152 mmHg [23]; diastolic blood pressure diazepam group=87 mmHg [16], control=87 mmHg [18]). Both groups showed significant blood pressure reduction on discharge (p<0.0001) but the difference in mean blood pressure reduction between the two groups was insignificant (systolic blood pressure p=0.16, 95% confidence interval [CI]=–5 to +19 mmHg; diastolic blood pressure p=0.43, 95% CI=–8 to +10 mmHg). Anxiety was significantly lower on discharge (p<0.0001) but the difference in mean fall in anxiety scores between the two groups was insignificant (p=0.08, 95% CI=0 to +2). There was no significant correlation between total diazepam and changes in blood pressure (systolic blood pressure p=0.32; diastolic blood pressure p=0.65) or anxiety (p=0.73), nor between blood pressure and anxiety on admission (systolic blood pressure p=0.45; diastolic blood pressure p=0.72).Conclusions: Elevated blood pressure and anxiety in acute epistaxis patients reduced on epistaxis resolution irrespective of oral diazepam use. The elevated blood pressure does not appear to be directly related to anxiety.

Exercise training reduces the sympathetic component of the blood pressure-heart rate baroreflex in man

1992 ◽  
Vol 82 (4) ◽  
pp. 357-362 ◽  
Author(s):  
Bronwyn A. Kingwell ◽  
Anthony M. Dart ◽  
Garry L. Jennings ◽  
Paul I. Korner
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Exercise Training ◽  
Sympathetic Activity ◽  
Blood Pressure Reduction ◽  
Maximal Oxygen Consumption ◽  
Pressure Reduction ◽  
Blood Pressure Elevation ◽  
Reflex Gain ◽  
The Difference

1. Exercise training reduces resting sympathetic activity, but the effects on sympathetic activation or withdrawal during baroreflex responses to blood pressure perturbations are controversial. The purpose of this study was to investigate the effects of training on both the vagal and sympathetic reflex heart rate responses to blood pressure changes. 2. Using 10 healthy males in a randomized cross-over design, we examined the effects of three 30 min cycling sessions at 70% of maximal capacity for 4 weeks on the steady-state reflex heart rate responses to perturbations in mean arterial pressure induced with injections of nitroprusside and phenylephrine. The method provides a sigmoidal relationship between changes in heart rate and blood pressure. The upper plateau (maximum tachycardia in response to blood pressure reduction) and lower plateau (maximum bradycardia in response to blood pressure elevation) are mainly mediated by the cardiac sympathetics and vagus, respectively. The slope of the relationship is a measure of reflex gain. 3. Training, which increased maximal oxygen consumption by 13 ± 2% (mean ± standard error of the difference), reduced supine and standing blood pressures by 3 ± 1 / 3 ± 1 mmHg (P < 0.05) and 4 ± 1/2 ± 2 mmHg (P < 0.05 for systolic), respectively, whereas resting heart rate was lowered by 6 ± 1 beats/min (P < 0.05). Reflex sensitivity in the presence of functioning vagus and sympathetics was not altered with training, but the vagal component of sensitivity, as assessed after sympathetic blockade with propranolol, was significantly reduced. The maximal tachycardiac responses to blood pressure decreases were consistently reduced with training (sedentary, 106 beats/ min; trained, 97 ± 1 beats/min; P < 0.05). This attenuation was not evident in the presence of propranolol, suggesting a sympathetic origin. 4. Exercise training thus reduced the sympathetic contribution to reflex tachycardia induced by blood pressure reduction and diminished the vagal contribution to reflex sensitivity. These effects of training may be of relevance to individuals with elevated sympathetic activity who may be at risk of myocardial ischaemia, serious ventricular arrhythmias or sudden cardiac death.

Improvement of Insulin Sensitivity Contributes to Blood Pressure Reduction After Weight Loss in Hypertensive Subjects With Obesity

Hypertension ◽  
1996 ◽  
Vol 27 (5) ◽  
pp. 1180-1186 ◽  
Author(s):  
Toshio Ikeda ◽  
Tomoko Gomi ◽  
Nobuhito Hirawa ◽  
Jun Sakurai ◽  
Nori Yoshikawa
Keyword(s):  
Blood Pressure ◽  
Weight Loss ◽  
Insulin Sensitivity ◽  
Blood Pressure Reduction ◽  
Pressure Reduction

scholarly journals SGLT2 inhibitors and lower limb complications: an updated meta‐analysis

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Chu Lin ◽  
Xingyun Zhu ◽  
Xiaoling Cai ◽  
Wenjia Yang ◽  
Fang Lv ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Lower Limb ◽  
Blood Pressure Reduction ◽  
Random Effect Model ◽  
Diabetic Patients ◽  
Controlled Trials ◽  
Pressure Reduction ◽  
Effect Model ◽  
Meta Regression

Abstract Background To exam the associations between the use of sodium glucose co-transporter 2 inhibitor (SGLT2i) and the risk of lower limb complications, and to analyze the associated factors. Methods Pubmed, Medline, Embase, the Cochrane Center Register of Controlled Trials for Studies and Clinicaltrial.gov were searched from the inception to November 2020. Randomized controlled trials of SGLT2i conducted in population containing diabetic patients with reports of amputation, peripheral arterial disease (PAD) and diabetic foot (DF) events were included. Random-effect model, fixed-effect model and meta-regression analysis were accordingly used. Result The numbers of SGLT2i users versus non-SGLT2i users in the analyses of amputation, PAD and DF were 40,925/33,414, 36,446/28,685 and 31,907/25,570 respectively. Compared with non-SGLT2i users, the risks of amputation and PAD were slightly increased in patients with canagliflozin treatment (amputation: OR = 1.60, 95% CI 1.04 to 2.46; PAD: OR = 1.53, 95 % CI 1.14 to 2.05). Meta-regression analyses indicated that greater weight reduction in SGLT2i users was significantly associated with the increased risks of amputation (β = − 0.461, 95% CI − 0.726 to − 0.197), PAD (β = − 0.359, 95% CI − 0.545 to − 0.172) and DF (β = − 0.476, 95% CI − 0.836 to − 0.116). Lower baseline diastolic blood pressure (β = − 0.528, 95% CI − 0.852 to − 0.205), more systolic blood pressure reduction (β = − 0.207, 95% CI − 0.390 to − 0.023) and more diastolic blood pressure reduction (β = − 0.312, 95% CI − 0.610 to − 0.015) were significantly associated with the increased risks of amputation, PAD and DF respectively in patients with SGLT2i treatment. Conclusions The risks of amputation and PAD were slightly increased in patients with canagliflozin treatment. Reductions in body weight and blood pressure were associated with lower limb complications in patients with SGLT2i treatment.

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