8. Rule of law

This chapter assesses the rule of law. The rule of law is a constitutional value or principle which measures good governance, fair law-making, and applying law in a just way. It acts as a protecting mechanism by preventing state officials from acting unfairly, unlawfully, arbitrarily, or oppressively. These are also key terms in judicial review. The rule of law is also regarded as an external measure for what a state does; if the rule of law breaks down in a state, it will fail to function in an internationally acceptable way. Ultimately, the core meaning of the rule of law is that the law binds everyone. This includes those in government, who must obey the law. Moreover, any action taken by the government must be authorised by law, that is, government needs lawful authority to act.

Ayurvedic management of vatakantak-plantar fasciitis – a case study

This study reveals effect of lepa of Jatamayadi churna and marma gulika with lemon juice in vatakantak. Main aim of this study was to report the fast and external measure of treatment for vatakantak. A 45 years male patient was treated with lepa of Jatamayadi churna and marma gulika with lemon juice. This paste was applied on affected area of heel and then covered with Arka Patra. Lepa was done at night and removed in the morning. Treatment was given for 3 weeks. Patient was assessed on the basis of subjective parameters such as pain, exaggerating factors for pain, difficulty in walking after sleep in the morning and tenderness. This study shows that without any internal medicine only lepa (external treatment) helps to relieve stabbing pain of vatakantak.

Using Evidence Factors to Clarify Exposure Biomarkers

A study has 2 evidence factors if it permits 2 statistically independent inferences about 1 treatment effect such that each factor is immune to some bias that would invalidate the other factor. Because the 2 factors are statistically independent, the evidence they provide can be combined using methods associated with meta-analysis for independent studies, despite using the same data twice in different ways. We illustrate evidence factors, applying them in a new way in investigations that have both an exposure biomarker and a coarse external measure of exposure to a treatment. To illustrate, we consider the possible effects of cigarette smoking on homocysteine levels, with self-reported smoking and a cotinine biomarker. We examine joint sensitivity of 2 factors to bias from confounding, a central aspect of any observational study.

Patients with chronic diseases: tomorrow, all sentinels?

Very old studies and clinical experiences of physicians already signal the ability of some patients to feel subclinical signs. These patients are called sentinel patients because they can anticipate crisis very early and therefore intervene quickly to prevent them. Studies have shown that these patients develop these skills from their own experience, in steps which are similar to quasi-experimental research. They test and adjust their competence all the more easily as they have an objective external measure available. This faculty of patients suggests the possibility of using medical devices as a means of learning for patients to tutor themselves in support of this singular skill.

7. Rule of law

This chapter assesses the rule of law. The rule of law is a constitutional value or principle which measures good governance, fair law-making, and applying law in a just way. It acts as a protecting mechanism by preventing state officials from acting unfairly, unlawfully, arbitrarily, or oppressively. These are also key terms in judicial review. The rule of law is also regarded as an external measure for what a state does; if the rule of law breaks down in a state, it will fail to function in an internationally acceptable way. Ultimately, the core meaning of the rule of law is that the law binds everyone. This includes those in government, who must obey the law. Moreover, any action taken by the government must be authorised by law, that is, government needs lawful authority to act.

Validation of the Brief Developmental Assessment in pre-school children with heart disease

IntroductionThe objective of this study was to prospectively validate the “Brief Developmental Assessment”, which is a new early recognition tool for neurodevelopmental abnormalities in children with heart disease that was developed for use by cardiac teams.MethodsThis was a prospective validation study among a representative sample of 960 pre-school children with heart disease from three United Kingdom tertiary cardiac centres who were analysed grouped into five separate age bands.ResultsThe “Brief Developmental Assessment” was successfully validated in the older four age bands, but not in the youngest representing infants under the age of 4 months, as pre-set validation thresholds were met – lower 95% confidence limit for the correlation coefficient above 0.75 – in terms of agreement of scores between two raters and with an external measure the “Mullen Scales of Early Learning”. On the basis of American Association of Pediatrics Guidelines, which state that the sensitivity and specificity of a developmental screening tool should fall between 70 and 80%, “Brief Developmental Assessment” outcome of Red meets this threshold for detection of Mullen scores >2 standard deviations below the mean.ConclusionThe “Brief Developmental Assessment” may be used to improve the quality of assessment of children with heart disease. This will require a training package for users and a guide to action for abnormal results. Further research is needed to determine how best to deploy the “Brief Developmental Assessment” at different time points in children with heart disease and to determine the management strategy in infants younger than 4 months old.

The Prevalence and Severity of Underreporting Bias in Machine- and Human-Coded Data

Textual data are plagued by underreporting bias. For example, news sources often fail to report human rights violations. Cook et al. propose a multi-source estimator to gauge, and to account for, the underreporting of state repression events within human codings of news texts produced by the Agence France-Presse and Associated Press. We evaluate this estimator with Monte Carlo experiments, and then use it to compare the prevalence and seriousness of underreporting when comparable texts are machine coded and recorded in the World-Integrated Crisis Early Warning System dataset. We replicate Cook et al.’s investigation of human-coded state repression events with our machine-coded events, and validate both models against an external measure of human rights protections in Africa. We then use the Cook et al. estimator to gauge the seriousness and prevalence of underreporting in machine and human-coded event data on human rights violations in Colombia. We find in both applications that machine-coded data are as valid as human-coded data.

Correlation Between In Vivo Knee Contact Forces and External Measures During Gait

Researchers have sought to explain the development and progression of knee osteoarthritis using in vivo estimates of knee contact forces. Unfortunately, it is not possible to measure knee contact forces in a clinical environment. Thus, studies often estimate knee contact forces using a variety of external measures. For example, inverse dynamics knee loads such as the adduction moment and superior force are frequently used as surrogate measures of medial and total knee contact force, respectively. Contraction of muscles spanning the knee is believed to increase knee contact force, and hence muscle electromyographic (EMG) signals are another external measure that may be indicative of internal contact force. The recent development of instrumented knee implants, such as the eTibia design [1], has provided access to in vivo knee contact force data during gait and other activities. However, few studies have correlated inverse dynamics loads, and none have correlated EMG signals, with total, medial, and lateral in vivo knee contact forces.