Gut Microbiota: A Key Regulator in the Effects of Environmental Hazards on Modulates Insulin Resistance

Insulin resistance is a hallmark of Alzheimer’s disease (AD), type II diabetes (T2D), and Parkinson’s disease (PD). Emerging evidence indicates that these disorders are typically characterized by alterations in the gut microbiota composition, diversity, and their metabolites. Currently, it is understood that environmental hazards including ionizing radiation, toxic heavy metals, pesticides, particle matter, and polycyclic aromatic hydrocarbons are capable of interacting with gut microbiota and have a non-beneficial health effect. Based on the current study, we propose the hypothesis of “gut microenvironment baseline drift”. According to this “baseline drift” theory, gut microbiota is a temporarily combined cluster of species sharing the same environmental stresses for a short period, which would change quickly under the influence of different environmental factors. This indicates that the microbial species in the gut do not have a long-term relationship; any split, division, or recombination may occur in different environments. Nonetheless, the “baseline drift” theory considers the critical role of the response of the whole gut microbiome. Undoubtedly, this hypothesis implies that the gut microbiota response is not merely a “cross junction” switch; in contrast, the human health or disease is a result of a rich palette of gut-microbiota-driven multiple-pathway responses. In summary, environmental factors, including hazardous and normal factors, are critical to the biological impact of the gut microbiota responses and the dual effect of the gut microbiota on the regulation of biological functions. Novel appreciation of the role of gut microbiota and environmental hazards in the insulin resistance would shed new light on insulin resistance and also promote the development of new research direction and new overcoming strategies for patients.

Environmental Hazards of an Unrecultivated Liquid Waste Disposal Site on Soil and Groundwater

Disposal sites without adequate engineering controls pose a significant risk to the environment. In the present study, the environmental hazards of an abandoned and unrecultivated liquid waste disposal are investigated with a special focus on soil and shallow groundwater contamination. After a period of operation from 1994 to 2010, when the wastewater collection of the municipality was regulated, the disposal site was subsequently decommissioned without further action. Eight monitoring wells have been established in the disposal basins and in the surrounding area to determine the contamination of the site. Sampling took place in the summers of 2020 and 2021. The results of the analysis of the soil and water samples collected showed a high level of contamination in the area. In the borehole profile of the infiltration basin, a well-developed leachate nitrate profile was observed, with a concentration above 3000 mg/kg NO3−. The soil phosphate content was also significant, with a value of over 1900 mg/kg in the upper 40 cm layer. Extremely high concentrations of ammonium (>45 mg/L) and organic matter (>90 mg/L) were detected in the groundwater of the basins, indicating that contaminated soil remains a major source of pollutants more than 10 years after closure. For all micro- and macroelements present in detectable concentrations, a significant increase was observed in the infiltration basin. Our results have revealed that the surroundings are also heavily contaminated. NO3− concentrations above the contamination limit were measured outside the basins. Recultivation of liquid waste disposal sites of similar characteristics is therefore strongly recommended.

Consistent Organochlorinated Pesticides (OPC) Residues Contamination in Beans Consumed in Gombe Metropolis Nigeria

Most of the locally consumed beans in our vicinity contain excess chemicals of pesticides residues which are harmful to humans and environmental hazards to ecosystem. Investigation of this study revealed contamination level of organochlorine pesticides residues in dried beans originating from Nigeria with a view to controlling them, it also studies crude fiber of beans showed that B4 has the highest fiber content, 27.85% and the order of decreasing value as B4, B5 , B1, B3 and B2. The least percentage of crude fiber was shown by B2 in all the beans samples analyzed. This study also investigated the pesticides residue components of the organochlorinated pesticides test. The presence of pesticide residues in all 14 types of organochlorine pesticides in beans is lower than a previously reported level. Despite this, the amount of organochlorine pesticides tested is more than the permitted levels of 0.01 to 0.2 mg/kg, indicating that the beans consumed in the Gombe metropolis included pesticide residues beyond the permissible limit.

Conflict of Interest Between Regulatory Agencies on Telecommunication Sector And Consequences of Improper Telecommunication Mast Installation in Nigeria

This paper examines various laws governing telecommunication installations in Nigeria with a view to addressing the perceived shortcomings in the laws. While the National Environmental Standards Regulatory and Enforcement Agency Act (NESREA Act) and the National Communications Commission (NCC Act) have been enacted to solve the problems associated with the effects of telecommunication mast installation in public places, the outcome of these laws seem inadequate for failure to provide effective means of enforcing same. The study considered the provisions of NESREA Act which is the principal Law enacted for ensuring that environ- mental standards are maintained and protected in Nigeria and the provisions of NCC Act which is the law that establishes the principal body which regulates telecommunication installations in Nigeria as well as other legislations. While NESREA in its Regulation provided for a setback of 10 metres, the NCC Act provided for a setback of 5 metres, which often conflicts and put victims at disadvantage and also conflict between the two regulatory bodies. It was observed that serious environmental hazards are linked to installation of tele- communication masts within/close to residential premises. Among these are leukemia, cancer, cracks on the buildings, pollution, such as water, land and air. The problems also include telecommunication masts falling on buildings and sometimes death due to sub- standard materials used in the installation as against the stated standard by the controlling regulatory bodies.

Technological and Economic Analysis of the Application of Surface Miner on the Example of a Limestone Deposit in Poland

Mining a deposit utilizing surface miner is very popular in many countries. Presently, a surfaceminer has also experimented with extracting different deposits: bauxite, hematite, sandstone, shale etc.Surface miners can completely eliminate drilling and blasting operation and primary crushing unit, thusreducing their associated environmental hazards. Apart from this, the sized excavated material increasestransport or conveying efficiency and saves the energy requirement in processing. So far, these machineshave not been used in Poland. To evaluate this technology, tests were carried out on one of the limestonedeposit in Poland. During these tests, basic parameters of efficiency, output quantity and mining costswere defined. The conducted tests have shown that this technology cannot be used in all geological andmining conditions. Therefore, the article presents the advantages and disadvantages of using surfaceminer, taking into account the Polish geological and mining conditions.