Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions

Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]

PENGARUH PENAMBAHAN SUPLEMEN HERBAL PADA PAKAN TERHADAP DIFERENSIASI LEUKOSIT IKAN DAN SINTASAN IKAN PATIN (Pangasionodon hypopthalmus)

The use of herbal supplements is an alternative to increase food security, because it can stimulate fish appetite and increase fish immunity against disease. The aims of this research to know the total leukocytes, leukocyte differentiation and survival rate of striped catfish fed with dosage fermented herbal supplements, and to obtain the best dosage. The implementation of research was from June until August 2019 at the Parasites and Fish Diseases Laboratory, Faculty of Fisheries and Marine, Riau University. The method used is a completely randomized design (CRD), with four treatments and three replications, namely P0 (without the addition of herbal supplements), P1 (herbal supplement dose 100 mL / kg of feed), P2 (200 mL / kg of feed), and P3 (300 mL / kg of feed). Maintenance of fish is carried out for 60 days, with a stocking density of 50 fish / m. The results showed that the herbal supplementation at a dose of 200 mL / kg of feed (P2) was the optimal dosage in stimulating total leukocytes and differentiation of catfish leukocytes. P2 treatment resulted in total leukocytes of 11.26 x 104 cells/mm3, further differentiation of leukocytes such as lymphocytes, monocytes, neutrophils and platelets of 81.67%, 6.33%, 5.67% and 6.33%. In addition it produces a survival rate of 100%. Key words : Fermented herbal supplement, striped catfish, total leukocytes

The effect of phytogenic feed additives on the performance, meat quality and coccidial infection rates of rabbits

The aim of the study was to evaluate the effect of herbal supplementation on rabbits’ health and production parameters. In experiment with herbal food additives, at 90 days of age animals fed with phytogenic additives (oregano, garlic and rosemary) had higher body weight compared to the group fed with coccidiostat. In experiment with herbal water additives (garlic extract or oregano) the phytobiotic supplementation had no effect on weight gains of animals. The highest body weight on slaughter day was obtained by rabbits drank water with garlic extract. Parasitological tests performed at 91 days of age showed that lowest average number of coccidia oocysts per gram of faeces (OPG) in “garlic” group (48.0 OPG) and the highest in control group (308.6 OPG). The research showed that feed with herbal supplementation is willingly eaten by rabbits, contributes to faster weight gains and has a positive effect on meat quality.