Metastatic gallbladder cancer to the ovary presenting as primary ovarian cancer: a case report

Background Krukenberg tumors are uncommon and are indicative of an ovarian metastatic carcinoma that originates from another site of primary malignancy. The majority of metastases to ovaries are derived from the stomach and colon. We present a rare case of a metastatic ovarian malignant tumor that originated from gallbladder adenocarcinoma. Case presentation A 45-year-old premenopausal Korean woman presented with abdominal distension. Bilateral multiseptated ovarian tumors and a wall-thickened gallbladder were found on abdominal computed tomography. The patient was diagnosed with metastatic ovarian carcinoma arising from gallbladder adenocarcinoma and was treated with adjuvant chemotherapy. Conclusions Metastases to the ovaries from other sites, including the gallbladder, are rare and usually resemble primary ovarian tumors. Therefore, potential metastatic ovarian tumors of newly diagnosed pelvic masses should be considered in differential diagnoses.

Les tumeurs de Krukenberg de l'ovaire d'origine rectale

Krukenberg tumors (TK) define themselves as ovarian metastases from cancer more often digestive. These are rare tumors that represent 1 to 2% of ovarian tumors. They are characterized by the presence of “kitten ring” cells filled with mucus and a pseudo-sarcomatous proliferation of the ovarian stroma. Their evolution is quickly fatal. We report 1 case of Krukenberg tumor observed and operated on in June 2020 at the surgery Department B CHU Constantine. The symptoms began with a rectal syndrome with transient episodes of pelvic pain. In this regard, we will recall the epidemiological, clinical, and evolutionary characteristics of this disease. Keywords: Krukenberg tumor, rectal cancer, ovarian metastases, synchronous tumors, posterior pelvectomy.

Krukenberg tumor in a young female arising from a primary adenocarcinoma of stomach: a case report

Krukenberg tumor is a malignancy of ovary that metastasizes from a primary site. Krukenberg tumors are uncommon and account for less than 2% of all ovarian tumors. It is usually a bilateral involvement of ovaries from the metastatic deposit from adenocarcinoma of the stomach. Krukenberg tumors mostly occur after 40 years. Metastatic ovarian tumors in young age are very rare. Here, we reported a very rare case of bilateral Krukenberg tumors of the ovaries arising from a primary adenocarcinoma of the stomach in a 20 year old Indian female.

Krukenberg Tumor: A Review of Prognostic Factors and Management

Aim: This review aims to summarize current evidence on Krukenberg Tumors (KT), addressing the main prognostic determinants and its’ management. Background: Krukenberg Tumors are rare metastatic tumors of the ovary. They were initially described by Friederich Ernst Krukenberg in 1896. They arise from extra-ovarian primary signet-ring cell carcinomas, being the gastrointestinal tract the most common site of origin. The most common clinical presentation of KT is an abdominal mass or discomfort in a premenopausal 40 to the 50-year-old woman. The prognosis is extremely poor compared to primary ovarian cancer. Results: Overall survival may vary significantly according to the choice and timing of treatment. The effective treatment strategies for KT are still controversial. However, therapeutic options include surgical resection as the mainstay of treatment when possible and the application of different Chemotherapy (CT) regimens. Conclusions: Several factors negatively affect prognosis: an incomplete metastasectomy, extensive disease at diagnosis and the origin of the tumor are the main factors that most authors agree incur in a worse prognosis. KT’s optimal therapeutic strategies are still a matter of debate, raising the need for more studies to achieve consensus.