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2021 ◽  
Vol 3 (2) ◽  
pp. 120
Author(s):  
Fatihatul Hayati

Complementary therapy in health care is a non-conventional treatment aimed at increasing the degree of public health. The terpi includes promotional, preventive, curative, and rehabilitative efforts that have proven their quality of safety, and effectiveness based on research and science (Evidence Based Medicine). In complementary therapy, the therapist treats various diseases or complaints using traditional techniques and is not done by surgery and drugs or pharmaceutical products, but by utilizing various types of therapy and herbs.The use of complementary therapies in the field of midwifery must be proven safe by research. Pregnant women are a group that is recommended to take advantage of complementary therapy or medicine in dealing with perceived complaints, because complementary therapy can avoid the side effects of conventional medicine and have great control over their own health. Although traditional / complementary medicine is relatively safer, it does not mean that it does not pose a risk, therefore pregnant women must have adequate knowledge about the use of safe complementary therapies during pregnancy.Health education on complementary therapies in pregnancy is provided by extension methods when pregnant women carry out motherhood classes in the working area of Puskesmas Putri Ayu, Jambi City. This activity was carried out in conjunction with the clinical practice of students of D III Midwifery Stikes Baiturrahim Jambi. 


2021 ◽  
Author(s):  
Molly Kozminsky ◽  
Thomas Carey ◽  
Lydia L. Sohn

Lipid-based nanoparticles have risen to the forefront of the COVID-19 pandemic—from encapsulation of vaccine components to modeling the virus, itself. Their rapid development in the face of the volatile nature of the pandemic requires high-throughput, highly flexible methods for characterization. DNA-directed patterning is a versatile method to immobilize and segregate lipid-based nanoparticles for subsequent analysis. DNA-directed patterning selectively conjugates oligonucleotides onto a glass substrate and then hybridizes them to complementary oligonucleotides tagged to the liposomes, thereby patterning them with great control and precision. The power of this method is demonstrated by characterizing a novel recapitulative lipid-based nanoparticle model of SARS-CoV-2 —S-liposomes— which present the SARS-CoV-2 spike (S) protein on their surfaces. Patterning of a mixture of S-liposomes and liposomes that display the tetraspanin CD63 into discrete regions of a substrate is used to show that ACE2 specifically binds to S-liposomes. Importantly, DNA-directed patterning of S-liposomes is used to verify the performance of a commercially available neutralizing antibody against the S protein. Ultimately, the introduction of S-liposomes to ACE2-expressing cells demonstrates the biological relevance of DNA-directed patterning. Overall, DNA-directed patterning enables a wide variety of custom assays for the characterization of any lipid-based nanoparticle.


2021 ◽  
Author(s):  
Molly Kozminsky ◽  
Thomas Carey ◽  
Lydia L. Sohn

Lipid-based nanoparticles have risen to the forefront of the COVID-19 pandemic—from encapsulation of vaccine components to modeling the virus, itself. Their rapid development in the face of the volatile nature of the pandemic requires high-throughput, highly flexible methods for characterization. DNA-directed patterning is a versatile method to immobilize and segregate lipid-based nanoparticles for subsequent analysis. DNA-directed patterning selectively conjugates oligonucleotides onto a glass substrate and then hybridizes them to complementary oligonucleotides tagged to the liposomes, thereby patterning them with great control and precision. The power of this method is demonstrated by characterizing a novel recapitulative lipid-based nanoparticle model of SARS-CoV-2 —S-liposomes— which present the SARS-CoV-2 spike (S) protein on their surfaces. Patterning of a mixture of S-liposomes and liposomes that display the tetraspanin CD63 into discrete regions of a substrate is used to show that ACE2 specifically binds to S-liposomes. Importantly, DNA-directed patterning of S-liposomes is used to verify the performance of a commercially available neutralizing antibody against the S protein. Ultimately, the introduction of S-liposomes to ACE2-expressing cells demonstrates the biological relevance of DNA-directed patterning. Overall, DNA-directed patterning enables a wide variety of custom assays for the characterization of any lipid-based nanoparticle.


2020 ◽  
Vol 38 (3) ◽  
pp. 350-356
Author(s):  
Alfredo Junior Paiola Albrecht ◽  
Leandro Paiola Albrecht ◽  
André Felipe Moreira Silva ◽  
Romulo Augusto Ramos ◽  
Everson Pedro Zeny ◽  
...  

Herbicide mixtures, use of multiple sites of action, and other weed management practices are necessary to avoid cases of biotype resistance. The aim of this study was to evaluate the efficiency of imazapic/imazapyr and other herbicides in mixtures to control Digitaria insularis at burndown before soybean sowing. This field research was conducted in Umuarama, State of Parana (PR), Brazil, in the 2018/19 soybean season. The experiment was conducted in a randomized block experimental design with four replications and 11 treatments composed of the application of glyphosate, clethodim, haloxyfop, imazapic/imazapyr, glufosinate, 2,4-dichlorophenoxyacetic acid (2,4-D), dicamba, triclopyr, and saflufenacil, in mixtures. Weed control was evaluated as well as soybean injury and yield. An analysis of variance and F-test were performed, and the treatment means were compared by the Scott-Knott test. All treatments showed great control over the weed and low crop injury rate while maintaining soybean yield. The application of imazapic/imazapyr in mixtures with other herbicides was effective in controlling glyphosate-resistant D. insularis in burndown before soybean sowing and with sequential application of haloxyfop + glyphosate at V3 stage of soybean. This chemical management was also selective for soybean.


2020 ◽  
Vol 9 (1) ◽  
pp. 26
Author(s):  
Rina Wahyu Setyaningrum ◽  
Fabiola Dharmawanti Kurnia ◽  
Ali Mustofa

Racism and Injustice have put Jefferson, a poor young black man, into an electrocution for murder and burglary that he has never done. As a coloured, he cannot do anything than accept the defense attorney verdict – white American Supreme Court’s desegregation – who addresses him as a “hog.” It leaves an inferior feeling that he is nothing but a hog.  Comparing him to a hog attracts Miss Emma’s protest that she would like him walking to the electric chair as a human. Therefore, to get Jefferson understands that he is worth a man, she asks Grant Wiggins – an educated black teacher to educate him so he could die a man. In fact, the biggest challenge Grant faces when he looks at Jefferson is his feeling of looking at himself as a man experiencing the same type of racism and discrimination at the oppressive white community. Whereas, educating Jefferson to be a man is difficult as he has to make himself confident with his existence before determining ways of assuring Jefferson as an existing man who will walk to the electric chair on two feet, not a hog. Educating is underpinning people to have great control over lives and surroundings. Its importance deals with functioning the knowledge significant to empower. This is convincing that Jefferson should be educated so that he will not degrade himself as coloured because of his inability to say even a word to defend himself. Using the existentialism philosophy, Grant and Jefferson’s educational commitment in A Lesson Before Dying is discussed based on five themes of Sartre’s existentialism. It reveals that Grant does not get any positive response once he starts teaching. Gradually, Jefferson speaks to him after being attracted by his personal feelings. Grant’s ultimate achievement is when he can make Jefferson writes a diary, to portray some individual matters. What Grant has accomplished is his ability to link the themes, relevant to the philosophy of education. Grant succeeds in transforming Jefferson as a man who has dignity. 


2020 ◽  
Vol 16 (2) ◽  
Author(s):  
Iván Fernando Vargas Ochoa ◽  
Richard Camilo Bravo Angarita ◽  
César Augusto Peña Cortes

Introduction: The present article is the product of the research "Advances in the mental control of a robotic hand", developed at the University of Pamplona in the year 2019. Problem: Currently one of the main problems presented by robotic hand prostheses is the way in which the user indicates the movements to be performed. Given this, the best results have been obtained using invasive systems. Objective: The main objective of the system is to allow a person to control the movements and / or gestures of a robotic hand using their thoughts, in such a way that the control is as natural and precise as possible. Methodology: Use is made of a non-invasive, low-cost brain-computer interface (BCI) for the generation of control system references. Results: The performance of the system is directly subject to the user's ability to recreate actions or movements in their mind; the more defined your thinking, the better the control response. Conclusion: Mind control represents a new challenge for users, but as it is used, it becomes a more natural and precise control method, offering great control possibilities to people who make daily use of robotic hand prostheses. Originality: Through this research, an alternative is formulated for the control of hand prostheses, which does not require invasive systems and has the advantage of being low cost. Limitations: Frustration, stress and external noise are factors that directly affect the performance of the system.


2020 ◽  
Vol 982 ◽  
pp. 51-58
Author(s):  
Fu Liang Jiang ◽  
Hong Bo Zhang ◽  
Wen Jun Zhang

Microfluidics has great control over the size and uniformity of microspheres, which has been widely used in fabrication of different types of microspheres such as core-shell microbubbles. Gelatin Methacrylate (GelMa) as a biodegradable material that is closely resemble to native extracellular matrix (ECM). Photocrosslinked GelMa microspheres have gained numerous concerns in biomedical applications especially in three-dimensional cell culture and tissue engineering. In this article, we presented a suitable core-shell cell carrier based on biocompatible GelMa microbubbles. Highly monodispersed microbubbles were fabricated using a non-planar flow focusing microfluidic device. Both intact and collapsed microbubbles morphology were characterized through scanning electron microscopy (SEM), where clear hollow structures were found resulting from the gas core collapsing during the manipulation process. Furthermore, human umbilical vein endothelial cells (HUVEC) were seeded in the existence of microbubbles. Cells adhesion, migration and proliferation were observed in one week. It was notable that cells maintained high level of cell viability throughout the experiment. GelMa microbubble surface was also covered with cells, which became a facile carrier for cell culturing and targeted cell delivery.


2019 ◽  
Vol 11 (2) ◽  
pp. 402
Author(s):  
Isabel Antón Juárez

Resumen: La pertenencia a una red de distribución selectiva puede ser muy positivo para un dis­tribuidor oficial. Esto es así porque puede beneficiarse del prestigio de la marca que comercializa. Este beneficio tiene su contrapartida y es que el distribuidor oficial debe acatar las reglas que el titular de la red le impone contractualmente. Uno de los aspectos en los que se puede ver condicionado y afectar a su actividad empresarial es en lo relativo a la venta on line. El titular de la red va a poder justificar restric­ciones en las ventas on line de sus distribuidores oficiales en aras de proteger el prestigio de la marca sin vulnerar las normas europeas de competencia. Esto se traduce en que al distribuidor oficial se le podría prohibir la venta en determinadas plataformas de comercio electrónico. Se podría decir que la situación actual beneficia a los titulares de las redes oficiales de distribución, ya que amparados en las normas europeas de competencia pueden incorporar cláusulas en los contratos de distribución selectiva que les permitan un gran control sobre la venta on line de sus distribuidores oficiales.Palabras clave: producto de lujo, marca, distribución selectiva, venta on line.Abstract: Being a member to a selective distribution network can be very positive for an official distributor. This is because the distributor can benefit from the prestige of the brand. This benefit has its opposite side because the official distributor must abide the rules that the owner of the network impo­ses contractually. One of the aspects in which the official distributor can see conditioned and affect its business activity is in relation to online sales. This is so because the owner of the network will be able to justify restrictions on the online sales of their official distributors in order to protect the prestige of the brand without violating European competition rules. This means that the official distributor could be prohibited from selling on certain e-commerce platforms. It could be said that the current situation benefits the holders of the official distribution networks, since covered by the European competition rules may incorporate clauses in the selective distribution contracts that allow them a great control over the online sale of their official distributors.Keywords: luxury product, trademark, selective distribution, ecommerce.


2018 ◽  
pp. 178-213
Author(s):  
Sujata S. Mody

Chapter 4 provides an overview and history of the modern Hindi short story as it developed in Sarasvatī from 1900 to 1920, under Dwivedi’s direction. Dwivedi did not explicitly articulate his vision for short fiction; however, as editor of a journal that pioneered the modern genre in Hindi, he exerted great control over its development. Drawing inspiration from Shakespeare, Poe, and Verne to Shriharsh and Tagore, among other influences, short story writers in Hindi experimented with adventure-romance, science fiction, horror, and historical fiction but eventually settled on subject matter that was more mundane than spectacular, as per Dwivedi’s agenda for language, literature, and nation.


2018 ◽  
Vol 8 (2) ◽  
pp. 5271-5274

GTAW well known as tungsten inert gas welding (TIG) commonly used to join thin sections of nonferrous metals like magnesium, copper and aluminium alloys. Allowing for stronger, higher quality welds the welding operator need great control on welding process. Because of short arc length, contact gap of filler electrode have to be maintain in a even way to maintain equal speed and depositing methods. Present work focuses on the TIG welding process and microstructure analysis of flaws in welding; also evaluate the mechanical properties of welded joints. The samples prepared as per ASTM weld samples, the extracted samples tested for microstructure, penetration and other mechanical tests. The results are showing good at the area of weld.


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