Communicating & Relating’s account of social systems defines “non-reductive interactionism” (versus “interactional reductionism”) because it rejects not only the common assumption that what is social is separate from what is individual, but also the assumptions that what is social and what is individual can be reduced to interaction. Non-reductive interactionism has implications for conceptualizing and for grounding accounts of human sociality, and for employing key concepts like communities of practice, accountability, choice, the moral order, artifacts, agency, and scripts. Conjoint co-constituting also has implications in choosing conversation analysis as a key conceptual framework, and in focusing on the participant’s perspective in accounting for human communicating. Chapter 6 offers an ethical basis for comparing conceptual frameworks, and employs it in select comparisons with prior accounts of communication.