Evaluating Post-COVID-19 Conditions

2021 ◽  
Vol 26 (6) ◽  
pp. 3-14
Author(s):  
Garson M. Caruso ◽  
Les Kertay ◽  
Christopher R. Brigham
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Management Strategies ◽  
Significant Problem ◽  
Test Results ◽  
Subjective Symptoms ◽  
Persistent Symptoms ◽  
Disability Status

Abstract Persistent symptoms, physical signs, and abnormal test results after acute coronavirus disease 2019 (COVID-19) illness have emerged as a significant problem in the current and ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus pandemic. Finding a rational balance between compelling subjective symptoms and limited objective findings in patients with post-COVID-19 conditions is challenging. We advise caution in adopting attributions, explanations, and management strategies, and especially in conferring formal disability status, for these disorders until we understand them more completely. The prevalent uncertainties threaten both overevaluation and overtreatment, with substantial personal and societal consequences, and all stakeholders need to be both intellectually open and cautious going forward. This article highlights several concerns in evaluating and treating patients with enduring COVID-19-related illness.

scholarly journals Thoracic surgery during the coronavirus disease 2019 (COVID-19) pandemic in Madrid, Spain: single-centre report

2020 ◽  
Vol 58 (5) ◽  
pp. 991-996
Author(s):  
Lucas Hoyos Mejía ◽  
Alejandra Romero Román ◽  
Mariana Gil Barturen ◽  
Maria del Mar Córdoba Pelaez ◽  
José Luis Campo-Cañaveral de la Cruz ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Infection Control ◽  
Thoracic Surgery ◽  
Hospital Care ◽  
Test Results ◽  
Single Centre ◽  
Emergency Procedures ◽  
Related Symptom ◽  
Hospital Stays ◽  
Lung Transplants

Abstract OBJECTIVES We reviewed the incidence of coronavirus disease 2019 cases and the postoperative outcomes of patients who had thoracic surgery during the beginning and at the highest point of transmission in our community. METHODS We retrospectively reviewed patients who had undergone elective thoracic surgery from 12 February 2020 to 30 April 2020 and were symptomatic or tested positive for severe acute respiratory syndrome coronavirus 2 infection within 14 days after surgery, with a focus on their complications and potential deaths. RESULTS Out of 101 surgical procedures, including 57 primary oncological resections, 6 lung transplants and 18 emergency procedures, only 5 cases of coronavirus disease 2019 were identified, 3 in the immediate postoperative period and 2 as outpatients. All 5 patients had cancer; the median age was 64 years. The main virus-related symptom was fever (80%), and the median onset of coronavirus disease 2019 was 3 days. Although 80% of the patients who had positive test results for severe acute respiratory syndrome coronavirus 2 required in-hospital care, none of them were considered severe or critical and none died. CONCLUSIONS These results indicate that, in properly selected cases, with short preoperative in-hospital stays, strict isolation and infection control protocols, managed by a dedicated multidisciplinary team, a surgical procedure could be performed with a relatively low risk for the patient.

scholarly journals Understanding the SARS-CoV-2 to Manage COVID-19

2020 ◽  
Vol 5 (03) ◽  
pp. 285-293
Author(s):  
Somdatta Karak ◽  
Vegesna Radha
Keyword(s):  
Disease Management ◽  
Nutritional Status ◽  
Scientific Community ◽  
Management Strategies ◽  
Treatment Strategies ◽  
The Novel ◽  
Test Results ◽  
Specific Data ◽  
Population Groups

AbstractThe entire scientific community have come together in the last eight months to understand the details of the novel SARS-CoV-2 virus that has caused the COVID-19 pandemic. We now have a fair idea of the main targets that should be looked into in depth to fight the virus. However, the data from different population groups on the different testing or treatment strategies is still largely lacking. Populations are diverse in terms of their genetics, nutritional status, microbiota, access to facilities, among many other factors. This article makes a case for looking into women-specific data on test results, response to disease management strategies, as well as mortality due to COVID-19, otherwise currently missing.

scholarly journals Updated Approaches against SARS-CoV-2

2020 ◽  
Vol 64 (6) ◽  
Author(s):  
Haiou Li ◽  
Yunjiao Zhou ◽  
Meng Zhang ◽  
Haizhou Wang ◽  
Qiu Zhao ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Severe Acute Respiratory Syndrome ◽  
Clinical Management ◽  
Management Strategies ◽  
Therapeutic Options ◽  
Preclinical Models ◽  
Adequate Evidence

ABSTRACT Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). There is a growing understanding of SARS-CoV-2 in virology, epidemiology, and clinical management strategies. However, no anti-SARS-CoV-2 drug or vaccine has been officially approved due to the absence of adequate evidence. Scientists are racing to develop a treatment for COVID-19. Recent studies have revealed many attractive therapeutic options, even if some of them remain to be further confirmed in rigorous preclinical models and clinical trials. In this minireview, we aim to summarize the updated potential approaches against SARS-CoV-2. We emphasize that further efforts are warranted to develop the safest and most effective approach.

scholarly journals Evolution of severe acute respiratory syndrome coronavirus 2 RNA test results in a patient with fatal coronavirus disease 2019: a case report

2020 ◽  
Vol 101 ◽  
pp. 82-88 ◽  
Author(s):  
Chen Shao ◽  
Hui Liu ◽  
Lingjia Meng ◽  
Lin Sun ◽  
Yankun Wang ◽  
...  
Keyword(s):  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Test Results

Top ten research priorities for problematic knee arthroplasty

2020 ◽  
Vol 102-B (9) ◽  
pp. 1176-1182
Author(s):  
John A. Mathews ◽  
Nicholas S. Kalson ◽  
Polly M. Tarrant ◽  
Andrew D. Toms ◽  
Keyword(s):  
Knee Arthroplasty ◽  
Healthcare Professionals ◽  
Management Strategies ◽  
Research Priorities ◽  
Persistent Symptoms ◽  
Relevant Evidence ◽  
Independent Information ◽  
James Lind Alliance ◽  
Initial Survey ◽  
The Uk

Aims The James Lind Alliance aims to bring patients, carers, and clinicians together to identify uncertainties regarding care. A Priority Setting Partnership was established by the British Association for Surgery of the Knee in conjunction with the James Lind Alliance to identify research priorities related to the assessment, management, and rehabilitation of patients with persistent symptoms after knee arthroplasty. Methods The project was conducted using the James Lind Alliance protocol. A steering group was convened including patients, surgeons, anaesthetists, nurses, physiotherapists, and researchers. Partner organizations were recruited. A survey was conducted on a national scale through which patients, carers, and healthcare professionals submitted key unanswered questions relating to problematic knee arthroplasties. These were analyzed, aggregated, and synthesized into summary questions and the relevant evidence was checked. After confirming that these were not answered in the current literature, 32 questions were taken forward to an interim prioritization survey. Data from this survey informed a shortlist taken to a final consensus meeting. Results A total of 769 questions were received during the initial survey with national reach across the UK. These were refined into 32 unique questions by an independent information specialist. The interim prioritization survey was completed by 201 respondents and 25 questions were taken to a final consensus group meeting between patients, carers, and healthcare professionals. Consensus was reached for ranking the top ten questions for publication and dissemination. Conclusions The top ten research priorities focused on pain, infection, stiffness, health service configuration, surgical and non-surgical management strategies, and outcome measures. This list will guide funders and help focus research efforts within the knee arthroplasty community. Cite this article: Bone Joint J 2020;102-B(9):1176–1182.

scholarly journals Sistem Informasi Stok Gudang Koperasi Menggunakan Supply Chain Management

2018 ◽  
Vol 8 (2) ◽  
pp. 203
Author(s):  
Arfiani Nur Khusna ◽  
Fahmi Ardhi Nugraha
Keyword(s):  
Supply Chain ◽  
Supply Chain Management ◽  
Management Strategies ◽  
Management Approach ◽  
Accurate Information ◽  
Test Results ◽  
Chain Management ◽  
Abc Classification ◽  
Management Flow

The cooperative is faced with the problem of how to keep the availability of goods in the warehouse sufficient, not experiencing upperstock or understock in the stock inventory system. The Supply Chain Management approach can help overcome the problem of availability of goods by integrating suppliers efficiently. The study aims to produce information about the stock of goods and the number of orders for the next period so that it can make a suitable budget plan. Collecting data is the first step and then designing the pattern of supply chain management flow, supply chain management strategies include the use of pareto ABC classification to give priority to supervision of inventory and determination of purchase points by calculating Economy Order Quantity (EOQ), process flow, implementation and testing. The system produces goods stock information that is able to provide accurate information about the remaining stock of goods in the warehouse along with calculation calculations for the purchase of each item at an economical price and amount, for the determination of product reorder time (Reorder Point), the average product lead time is 2 days, the usage rate per day for rice is 0.34 and the safety stock of rice is 20 sacks so that if the rice has reached the 3 point sack then the cooperative must re-order. The test results using usability test showed that 66.66% of the questions were able to be answered by the respondents and the test results between 65-84% were declared good so that the application was feasible and usable.

scholarly journals LETTER TO THE EDITOR: COVID-19 AND THE CHALLENGES OF FRAILTY SCREENING IN OLDER ADULTS

2020 ◽  
pp. 1-2 ◽  
Author(s):  
R. O’Caoimh ◽  
S. Kennelly ◽  
E. Ahern ◽  
S. O’Keeffe ◽  
R.R. Ortuño
Keyword(s):  
Older Adults ◽  
Severe Acute Respiratory Syndrome ◽  
Healthcare Professionals ◽  
Management Strategies ◽  
Careful Examination ◽  
Geriatric Syndromes ◽  
Clinical Frailty Scale ◽  
The Impact ◽  
Recent Editorial ◽  
The Relationship

We read with interest the recent editorial examining the relationship between geriatric syndromes and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of Covid-19 (1), particularly the authors recognition of the need to identify frailty among older adults presenting with suspected symptoms and the importance of mobilising a range of healthcare professionals to tackle this disease (1). However, the identification of frailty and the utilisation of screening instruments by those without geriatric training and especially in acute care is challenging. Frailty is a complex condition. While age-associated, it is multi-dimensional and remains difficult to define (2). Although the Covid-19 pandemic has disproportionately affected older adults (1), data are lacking and pathophysiological mechanisms and the impact of differential management strategies on the course of the disease among older adults is uncertain (1). Further, the prevalence of frailty among those diagnosed, admitted or dying is not clearly reported at present. Nevertheless, the rationale for using frailty to identify those at risk and to allocate care has been correctly highlighted (1). We suggest however, that the use of instruments such as the Clinical Frailty Scale (CFS) (3) and particularly by non-specialised staff in this setting warrants more careful examination.

scholarly journals Nightlife clusters of coronavirus disease in Tokyo between March and April 2020

2020 ◽  
Vol 148 ◽  
Author(s):  
S. Takaya ◽  
S. Tsuzuki ◽  
K. Hayakawa ◽  
A. Kawashima ◽  
A. Okuhama ◽  
...  
Keyword(s):  
Propensity Score ◽  
Severe Acute Respiratory Syndrome ◽  
Propensity Score Matching ◽  
Tertiary Hospital ◽  
Test Results ◽  
Inclusive Approach ◽  
Pcr Test

Abstract We analysed associations between exposure to nightlife businesses and severe acute respiratory syndrome coronavirus 2 PCR test results at a tertiary hospital in Tokyo between March and April 2020. A nightlife group was defined as those who had worked at or visited the businesses. We included 1517 individuals; 196 (12.9%) were categorised as the nightlife group. After propensity score matching, the proportion of positive PCR tests in the nightlife group was significantly higher than that in the non-nightlife group (nightlife, 63.8%; non-nightlife, 23.0%; P < 0.001). An inclusive approach to mitigate risks related to the businesses needs to be identified.

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