Levels of antibody to Staphylococcus epidermidis in patients with acne vulgaris

1965 ◽  
Vol 92 (1) ◽  
pp. 88-90 ◽  
Author(s):  
S. M. Puhvel
2019 ◽  
Vol 46 (9) ◽  
pp. 782-786
Author(s):  
Keisuke Nakase ◽  
Aoi Yoshida ◽  
Hikaru Saita ◽  
Nobukazu Hayashi ◽  
Setsuko Nishijima ◽  
...  

Author(s):  
Abdul Hafeez ◽  
Shmmon Ahmad ◽  
Anmar Al- Taie

Acne vulgaris is most common dermatological condition that affects more than 70% of teenagers and more than 10% of adults. The moisture content of human skin makes it appear young and primary function of moisturizer is to avoid the dehydration by preventing the moisture loss. Natural therapies are more suitable and they are more reliable with less or no side effects. The current research focused on the use of herbs for treating acne vulgaris as a moisturizer. This research focused on the use of Azadirachta indica, Curcuma longa, and Ocimum sanctum to prepare the formulation, Azadiracta indica, Ocimum sanctum and Curcuma longa possessed the significant capability for inhibiting acne. The antimicrobial activity was evaluated against the Staphylococcus aureus, Staphylococcus epidermidis and Propionibacterium by disc diffusion method. Prepared formulations were tested for physical parameters such as pH, spreadability, viscosity and color. Formulation studies was found to optimum for all parameters. The study showed the anti-acne moisturizer was significantly effective in controlling the bacteria which cause acne, i.e. Staphylococcus aureus, Staphylococcus epidermidis and Propionibacterium. From this research, can be inferred that formulated herbal anti-acne moisturizer was related with a substantial decrease in the growth of microbes that causes acne.


2020 ◽  
Vol 3 (1) ◽  
pp. 42-50
Author(s):  
Wahyudi ◽  
Ayu Syahfitri ◽  
Syukur Berkat Waruwu ◽  
Dian Ika Perbina

Acne is one problem in adolescents and adults who can reduce self-confidence. This study aimed to formulate the combination cream of African leaf extract and palm oil leaves to determine the antibacterial activity of African leaf extract against several acne-causing bacteria (Propionibacterium acne and Staphylococcus epidermidis). Test antibacterial activity of extracts and cream with disc diffusion method. The cream is made with concentration of 5, 10 and 20% w/w. The evaluation results of cream with concentration of 5, 10 and 20% were physically stable for 4 weeks of storage at temperature room, homogeneous, pH and it did not cause irritation. Based on the test results, a combination of African leaf extract with concentration of 5% effectively inhibited bacterial growth with an average inhibition zone diameter of 12.06 mm for Propionibacterium acne bacteria and 13.63 mm for Staphylococcus epidermidis bacteria. The result of this study suggest that combination of African leaf extract and palm leaves posses potent anti-bacterial activity against Propionibacterium acne and Staphylococcus epidermidis.


2009 ◽  
Vol 55 ◽  
pp. 3-22 ◽  
Author(s):  
Marija Glavas Dodov ◽  
Svetlana Kulevanova

Acne vulgaris (acne) is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules) and non-inflammatory (comedones, open and closed) lesions. Propionibacterium acnes and Staphylococcus epidermidis are common pus-forming microbes responsible for the development of various forms of acne. This disease remains a common condition in industrialized societies, with many mainstream treatment options available. There are many acne products on the market, and making an appropriate selection can be daunting. Common therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy. Topically used agents are benzoyl peroxide, antibiotics and retinoid. Systemically used agents are antibiotics and isotretinoin. However, all such treatments carry risks and none is completely satisfactory. Natural alternatives are gaining greater research support, and have much to offer clinically in this disorder. This review focuses primarily on herbal treatments for acne that show scientific evidence of clinical efficacy, as well as the more common herbs shown to be useful in the treatment of this dermatologic disorder.


2019 ◽  
Vol 28 (1) ◽  
pp. 21-7 ◽  
Author(s):  
Irma Bernadette Simbolon Sitohang ◽  
Hafizah Fathan ◽  
Evita Effendi ◽  
Mardiastuti Wahid

BACKGROUND Acne vulgaris is a pilosebaceous disorder. Bacterial activity and inflammation both influence acne formation. Antibiotics suppress the bacterial activities and elicit anti-inflammatory effects. The overuse of antibiotics may lead to resistance in bacteria. This study was aimed to provide an overview of bacteria that may cause acne and determine their susceptibility to antibiotics.METHODS This was a cross-sectional study sampling from 93 patients with acne in Ciptomangunkusumo Hospital. Comedones were extracted and cultured on Brucella blood agar, under aerobic and anaerobic conditions at 35oC for 24–48 hours. Bacterial identification was performed using Vitek®, and susceptibility test using E-test. Data interpretation was based on the Clinical and Laboratory Standards Institute 2015.RESULTS Staphylococcus epidermidis (50.5%), Propionibacterium acnes (11.0%), and Staphylococcus aureus (7.7%) were identified. Bacteria were not found in 69.2% and 1.1% of samples in anaerobic and aerobic cultures, respectively. P. acnes was susceptible to doxycycline (100%) and minocycline (100%), while 10% was resistant to erythromycin, clindamycin, and tetracycline. S. epidermidis was susceptible to minocycline (100%); but resistant to erythromycin (65.2%), clindamycin (52.2%) and tetracycline (32.6%). The susceptibility of S. epidermidis to doxycycline was 89.1%, which was lower than that of P. acnes (100%). S. aureus was found to be sensitive to minocycline (100%), doxycycline (71.4%), clindamycin (71.4%), and tetracycline (71.4%); but it was resistant to erythromycin (42.9%).CONCLUSIONS Doxycycline and minocycline showed 100% effectiveness for P. acnes. The isolated bacteria were more susceptible to doxycycline compared to tetracycline. The use of clindamycin and erythromycin needs to be limited as most S. epidermidis isolates were resistant to both.


1980 ◽  
Vol 14 (7-8) ◽  
pp. 498-506
Author(s):  
A.J.M. Vermorken ◽  
C.M.A.A. Goos

Acne vulgaris is a disorder of the skin which begins with the accumulation of sebum in the sebaceous duct. The pressure built up by the accumulated sebum can rupture the duct. Diffusion of the sebum, particularly of its fatty acids, into the skin brings about an inflammatory reaction often accompanied by an infection. Besides causing infection, the bacteria produce lipases that stimulate the inflammatory processes by hydrolyzing the sebum into fatty acids. These effects can be attributed to both Corynebacterium acnes and Staphylococcus epidermidis. The way in which both oral and topical antibiotics can be used in, the treatment of acne is reviewed. The possibility for combined local treatment with an antibiotic and an antiandrogen is discussed.


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