scholarly journals The Effect of Orlistat-Induced Weight Loss, Without Concomitant Hypocaloric Diet, on Cardiovascular Risk Factors and Insulin Sensitivity in Young Obese Chinese Subjects With or Without Type 2 Diabetes

2002 ◽  
Vol 162 (21) ◽  
pp. 2428 ◽  
Author(s):  
Peter C. Y. Tong ◽  
Zoe S. K. Lee ◽  
Man-Mei Sea ◽  
Chun-Chung Chow ◽  
Gary T. C. Ko ◽  
...  
Diabetes Care ◽  
2011 ◽  
Vol 34 (7) ◽  
pp. 1481-1486 ◽  
Author(s):  
R. R. Wing ◽  
W. Lang ◽  
T. A. Wadden ◽  
M. Safford ◽  
W. C. Knowler ◽  
...  

2012 ◽  
Vol 21 (5) ◽  
pp. 608-617 ◽  
Author(s):  
Bethany Barone Gibbs ◽  
Frederick L Brancati ◽  
Haiying Chen ◽  
Mace Coday ◽  
John M Jakicic ◽  
...  

2000 ◽  
Vol 25 (6) ◽  
pp. 466-491 ◽  
Author(s):  
Catrine E. Tudor-Locke ◽  
Rhonda C. Bell ◽  
Anita M. Myers

There is tremendous potential for improving glycemic control, insulin sensitivity, and cardiovascular risk factors through increased physical activity in individuals with Type 2 diabetes. The demonstrated effects of structured endurance exercise on select outcomes compare favourably with those of typical pharmacological treatment modalities. Adherence to these types of program is problematic, however. We know less about the expected effects of lifestyle-based physical activity. Preliminary results require further investigation, given the apparent acceptability of these programs in this population, however. The effects of resistance training on cardiovascular risk factors to date likely limit its application as an adjunctive therapy for individuals with Type 2 diabetes. The question is no longer "can exercise/physical activity benefit the individual with Type 2 diabetes?" The answer is yes. Future research needs to refine questions regarding type, dose, and magnitude of effects of physical activity (and its subcategory exercise) on glycemic control, insulin sensitivity, and on risk factors for cardiovascular disease within the context of program acceptability and feasibility. Key words: walking, obesity, glycemic control, insulin sensitivity, hypertension


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