scholarly journals Connective-Tissue Fibroblasts Established on Micropillar Interfaces are Pivotal for Epithelial-Tissue Morphogenesis

2008 ◽  
Vol 18 (21) ◽  
pp. NA-NA
Author(s):  
Eva Mussig ◽  
Thorsten Steinberg ◽  
Simon Schulz ◽  
Joachim P. Spatz ◽  
Jens Ulmer ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Epithelial Tissue ◽  
Tissue Morphogenesis

Connective-Tissue Fibroblasts Established on Micropillar Interfaces are Pivotal for Epithelial-Tissue Morphogenesis

2008 ◽  
Vol 18 (19) ◽  
pp. 2919-2929 ◽  
Author(s):  
Eva Mussig ◽  
Thorsten Steinberg ◽  
Simon Schulz ◽  
Joachim P. Spatz ◽  
Jens Ulmer ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Epithelial Tissue ◽  
Tissue Morphogenesis

scholarly journals Segmentation and Tracking of Adherens Junctions in 3D for the Analysis of Epithelial Tissue Morphogenesis

2015 ◽  
Vol 11 (4) ◽  
pp. e1004124 ◽  
Author(s):  
Rodrigo Cilla ◽  
Vinodh Mechery ◽  
Beatriz Hernandez de Madrid ◽  
Steven Del Signore ◽  
Ivan Dotu ◽  
...  
Keyword(s):  
Adherens Junctions ◽  
Epithelial Tissue ◽  
Tissue Morphogenesis ◽  
Segmentation And Tracking

Migration and development of the blood fluke Sanguinicola inermis Plehn, 1905 (Trematoda: Sanguinicolidae) in carp, Cyprinus carpio L

Parasitology ◽  
1996 ◽  
Vol 113 (3) ◽  
pp. 279-285 ◽  
Author(s):  
R. S. Kirk ◽  
J. W. Lewis
Keyword(s):  
Quantitative Analysis ◽  
Connective Tissue ◽  
Cyprinus Carpio ◽  
Egg Production ◽  
Blood System ◽  
Epithelial Tissue ◽  
Serial Sections ◽  
Maximum Life Span ◽  
Carp Cyprinus Carpio ◽  
Migration And Development

SUMMARYThe migration and development of Sanguinicola inermis in carp fingerlings were investigated by quantitative analysis of serial sections of fish and examination of flukes from hosts up to 90 days p.i. Cercariae penetrated through the epidermis and migrated through connective tissue and muscle to establish in the blood system and commence egg production within 28 days p.i. Most flukes established in the ventral blood system and released eggs which accumulated in gill epithelial tissue. A minority of flukes inhabited dorsal blood vessels and shed eggs which lodged in connective tissue and visceral sites. Maximum life-span of the parasite is between 56 and 70 days p.i. and egg production peaked at day 42 p.i.

Pressure-Tuning FT-IR Study of Human Cervical Tissues

1993 ◽  
Vol 47 (7) ◽  
pp. 1058-1063 ◽  
Author(s):  
Patrick T. T. Wong ◽  
Rita K. Wong ◽  
Michael Fung Kee Fung
Keyword(s):  
Connective Tissue ◽  
Infrared Spectra ◽  
Frequency Region ◽  
Epithelial Tissue ◽  
Malignant Tissue ◽  
Tissue Samples ◽  
Pressure Tuning ◽  
Exfoliated Cells ◽  
Ft Ir ◽  
Ir Study

Infrared spectra of the normal connective, the normal epithelial, and the malignant epithelial tissues of cervix from seven patients have been measured as a function of pressure. Extremely high quality spectra of these tissue samples have been obtained. Consequently, structural differences at the molecular level among these three types of cervical tissues have been extracted from their pressure-tuning infrared spectra in the regions of the symmetric and antisymmetric stretching modes of phosphodiester groups, the C-O stretching mode, the CH2 bending mode, and the amide I mode. Significant differences in many features between the infrared spectra of the normal and the malignant cervical tissues and cells suggest that the infrared spectra of exfoliated cells and the biopsy of cervical tissues may be used in rapid evaluation of cervical cancer or in screening of large-volume normal cervical specimens. The infrared spectrum of the normal connective tissue of cervix in the frequency region 950 to 1100 cm−1 is similar to that of the malignant cervical tissue and cells. Therefore, if only this region of the spectrum is examined, the normal connective tissue will be misinterpreted as malignant tissue. However, the normal connective tissue can be differentiated unambiguously from the malignant tissue or the normal epithelial tissue by the infrared spectra in the frequency region 1200 to 1500 cm−1, where several well-defined sharp bands are unique for the normal connective tissue.

scholarly journals Unified quantitative characterization of epithelial tissue development

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Boris Guirao ◽  
Stéphane U Rigaud ◽  
Floris Bosveld ◽  
Anaïs Bailles ◽  
Jesús López-Gay ◽  
...  
Keyword(s):  
Cell Shape ◽  
Tissue Growth ◽  
Epithelial Tissue ◽  
Tissue Development ◽  
Tissue Morphogenesis ◽  
Quantitative Characterization ◽  
Cell Shape Changes ◽  
The Impact ◽  
Shape Changes

Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses. We developed a multiscale formalism that relates the characterizations of each cell process to tissue growth and morphogenesis. Having validated the formalism on computer simulations, we quantified separately all morphogenetic events in the Drosophila dorsal thorax and wing pupal epithelia to obtain comprehensive statistical maps linking cell and tissue scale dynamics. While globally cell shape changes, rearrangements and divisions all significantly participate in tissue morphogenesis, locally, their relative participations display major variations in space and time. By blocking division we analyzed the impact of division on rearrangements, cell shape changes and tissue morphogenesis. Finally, by combining the formalism with mechanical stress measurement, we evidenced unexpected interplays between patterns of tissue elongation, cell division and stress. Our formalism provides a novel and rigorous approach to uncover mechanisms governing tissue development.

scholarly journals Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Lucie E. Charrier ◽  
Elise Loie ◽  
Patrick Laprise
Keyword(s):  
Epithelial Tissue ◽  
Tissue Morphogenesis

scholarly journals Effect of Hyaluronic Acid Filler Injection on the Interdental Papilla in a Mouse Model of Open Gingival Embrasure

2020 ◽  
Vol 17 (14) ◽  
pp. 4956
Author(s):  
Soo-Bin Kim ◽  
Jaehun Cho ◽  
Seong-Suk Jue ◽  
Jae Hyun Park ◽  
Ji- Youn Kim
Keyword(s):  
Hyaluronic Acid ◽  
Connective Tissue ◽  
Mouse Model ◽  
Epithelial Tissue ◽  
Post Injection ◽  
Histological Changes ◽  
Filler Injection ◽  
Injection Group ◽  
Tnf Α ◽  
Interdental Papilla

The black triangle resulting from interdental papilla (IDP) loss is associated with poor aesthetics and difficulty in pronunciation and food impaction. There is limited knowledge of gingival tissue inflammatory response to hyaluronic acid (HA) filler injection, a minimally invasive IDP reconstruction method. This study aimed to examine the morphological and histological changes in IDP and the inflammatory cytokine localization to the IDP post-HA filler injection using an open gingival embrasure (OGE) mouse model. Mice from the control, sham, and OGE groups were attached with reference, inactive, and activated wires for 5 days, respectively. The degree of IDP loss was determined based on the spring-papilla distance (SPD). Morphological and histological changes in the OGE group injected with phosphate-buffered saline (PBS) or HA fillers were examined on days 2 and 7 post-injection. Immunohistochemical analysis was performed to determine the localization patterns of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, myeloperoxidase (MPO), and Ki67. Five days post-wire attachment, the control and OGE groups exhibited a significantly higher SPD than the sham group (p < 0.0167). The SPD of the HA filler injection group was significantly lower than that of the PBS injection group on days 2, 4, and 7 post-injection (p < 0.05). The IDP of the OGE group was wide and flat. HA filler was stable in the connective tissue underlying the epithelial tissue even on day 7 post-injection. TNF-α, IL-1β, IL-6, MPO, and Ki67 were highly localized to the connective tissue surrounding the filler on day 2, which decreased on day 7 post-injection. Thus, HA filler can safely and successfully reconstruct the IDP in cases of OGE.

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