scholarly journals Injectable Granular Hydrogels with Multifunctional Properties for Biomedical Applications

2018 ◽  
Vol 30 (20) ◽  
pp. 1705912 ◽  
Author(s):  
Joshua E. Mealy ◽  
Jennifer J. Chung ◽  
Heon-Ho Jeong ◽  
David Issadore ◽  
Daeyeon Lee ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Multifunctional Properties

scholarly journals Gold coated magnetic nanoparticles: from preparation to surface modification for analytical and biomedical applications

2016 ◽  
Vol 52 (48) ◽  
pp. 7528-7540 ◽  
Author(s):  
Saimon Moraes Silva ◽  
Roya Tavallaie ◽  
Lydia Sandiford ◽  
Richard D. Tilley ◽  
J. Justin Gooding
Keyword(s):  
Analytical Chemistry ◽  
Surface Modification ◽  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Multifunctional Properties

Gold coated magnetic nanoparticles (Au@MNPs) have become increasingly interesting to nanomaterial scientists due to their multifunctional properties and their potential in both analytical chemistry and nanomedicine.

scholarly journals Preparation and Properties of Magnetic Iron Oxide Nanoparticles for Biomedical Applications: A Brief Review

2020 ◽  
Vol 75 (1) ◽  
pp. 10-18
Author(s):  
Mostafa Yusefi ◽  
Kamyar Shameli ◽  
Ahmad Faris Jumaat
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Vital Role ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
Research Areas ◽  
Co Precipitation ◽  
Multifunctional Properties

Magnetic Iron oxide in nanostructure form with multifunctional properties may play a vital role in myriad biomedical applications. Iron oxide nanoparticles (IONPs) are fabricated via various methods, including thermal decomposition, co-precipitation, polyol, bio-mineralization, and green synthesis processes. Therefore, different researchers produced IONPs via various techniques to show better water permeability, antioxidant activity, biocompatibility, biodegradability, and lower or no toxicity, as advantages compared to commercial magnetic agents used in innovative applications for modern societies. This review explains various fabrication methods of IONPs and their multifunctional properties. Overall, the new advanced approaches, issues and main challenges, surface modification and modern applications of IONPs are considered. Lastly, some future developments and the views in these research areas are also discussed.

Preparation of fluorescent Au–SiO2 core–shell nanoparticles and nanorods with tunable silica shell thickness and surface modification for immunotargeting

2016 ◽  
Vol 4 (32) ◽  
pp. 5418-5428 ◽  
Author(s):  
Prakash D. Nallathamby ◽  
Juliane Hopf ◽  
Lisa E. Irimata ◽  
Tracie L. McGinnity ◽  
Ryan K. Roeder
Keyword(s):  
Biomedical Applications ◽  
Shell Thickness ◽  
Silica Shell ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Size Dependent ◽  
Scalable Methods ◽  
Core Shell Nanoparticles ◽  
Multifunctional Properties

Scalable methods for preparing and modifying Au–SiO2 core–shell nanoparticles provide a platform for engineering size-dependent multifunctional properties for in vivo biomedical applications.

In vitro and in vivo assessments of a 3-(3,4-dihydroxyphenyl)-2-propenoic acid bioconjugated gelatin-based injectable hydrogel for biomedical applications

2015 ◽  
Vol 3 (7) ◽  
pp. 1230-1244 ◽  
Author(s):  
S. Thirupathi Kumara Raja ◽  
T. Thiruselvi ◽  
R. Aravindhan ◽  
Asit Baran Mandal ◽  
A. Gnanamani
Keyword(s):  
Drug Delivery ◽  
Wound Healing ◽  
Biomedical Applications ◽  
Adhesive Material ◽  
Injectable Hydrogel ◽  
Propenoic Acid ◽  
Multifunctional Properties

A novel bioconjugated injectable hydrogel with multifunctional properties for wound healing and drug delivery: a biomimetic adhesive material.

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

How SIMS microscopy can be used in medicine

1992 ◽  
Vol 50 (2) ◽  
pp. 1602-1603
Author(s):  
Philippe Fragu
Keyword(s):  
Mass Spectrometry ◽  
Biomedical Applications ◽  
Secondary Ion Mass Spectrometry ◽  
Chemical Elements ◽  
Biological Applications ◽  
The Past ◽  
Potential Source ◽  
Secondary Ion ◽  
Chemical Integrity ◽  
Scientific Endeavour

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.

Biomedical applications: Pitfalls in the practice

1994 ◽  
Vol 52 ◽  
pp. 378-379
Author(s):  
J. D. Shelburne ◽  
Peter Ingram ◽  
Victor L. Roggli ◽  
Ann LeFurgey
Keyword(s):  
Operating Room ◽  
Liquid Nitrogen ◽  
Lung Tissue ◽  
Biomedical Applications ◽  
Microprobe Analysis ◽  
Tissue Sample ◽  
Cellular Level ◽  
Tissue Samples ◽  
Asbestos Fibers

At present most medical microprobe analysis is conducted on insoluble particulates such as asbestos fibers in lung tissue. Cryotechniques are not necessary for this type of specimen. Insoluble particulates can be processed conventionally. Nevertheless, it is important to emphasize that conventional processing is unacceptable for specimens in which electrolyte distributions in tissues are sought. It is necessary to flash-freeze in order to preserve the integrity of electrolyte distributions at the subcellular and cellular level. Ideally, biopsies should be flash-frozen in the operating room rather than being frozen several minutes later in a histology laboratory. Electrolytes will move during such a long delay. While flammable cryogens such as propane obviously cannot be used in an operating room, liquid nitrogen-cooled slam-freezing devices or guns may be permitted, and are the best way to achieve an artifact-free, accurate tissue sample which truly reflects the in vivo state. Unfortunately, the importance of cryofixation is often not understood. Investigators bring tissue samples fixed in glutaraldehyde to a microprobe laboratory with a request for microprobe analysis for electrolytes.

Biological and biomedical applications of collagenous biomaterials

1990 ◽  
Vol 48 (3) ◽  
pp. 856-857
Author(s):  
Yasushi P. Kato ◽  
Michael G. Dunn ◽  
Frederick H. Silver ◽  
Arthur J. Wasserman
Keyword(s):  
Biomedical Applications ◽  
Soft Tissues ◽  
Collagen Fibers ◽  
Bone Collagen ◽  
Cover Slip ◽  
Fibroblast Migration ◽  
Cellular Expression ◽  
Defect Repair

Collagenous biomaterials have been used for growing cells in vitro as well as for augmentation and replacement of hard and soft tissues. The substratum used for culturing cells is implicated in the modulation of phenotypic cellular expression, cellular orientation and adhesion. Collagen may have a strong influence on these cellular parameters when used as a substrate in vitro. Clinically, collagen has many applications to wound healing including, skin and bone substitution, tendon, ligament, and nerve replacement. In this report we demonstrate two uses of collagen. First as a fiber to support fibroblast growth in vitro, and second as a demineralized bone/collagen sponge for radial bone defect repair in vivo.For the in vitro study, collagen fibers were prepared as described previously. Primary rat tendon fibroblasts (1° RTF) were isolated and cultured for 5 days on 1 X 15 mm sterile cover slips. Six to seven collagen fibers, were glued parallel to each other onto a circular cover slip (D=18mm) and the 1 X 15mm cover slip populated with 1° RTF was placed at the center perpendicular to the collagen fibers. Fibroblast migration from the 1 x 15mm cover slip onto and along the collagen fibers was measured daily using a phase contrast microscope (Olympus CK-2) with a calibrated eyepiece. Migratory rates for fibroblasts were determined from 36 fibers over 4 days.

Multifunctional metal–organic framework heterostructures for enhanced cancer therapy

2021 ◽  
Author(s):  
Jintong Liu ◽  
Jing Huang ◽  
Lei Zhang ◽  
Jianping Lei
Keyword(s):  
Cancer Therapy ◽  
General Principle ◽  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Functional Modulation ◽  
Organic Framework

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.

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