Iridium Oxide Nanoparticle–Protein Corona Neural Interfaces with Enhanced Electroactivity and Bioactivity Enable Electrically Manipulatable Physical and Chemical Neuronal Activation

2021 ◽  
pp. 2100694
Author(s):  
Fu‐Erh Chan ◽  
Huei‐Min Syu ◽  
Te‐Yi Wang ◽  
Zheng‐Ting Tang ◽  
Chih‐Ning Huang ◽  
...  
Author(s):  
Pranvera Breznica ◽  
Rozafa Koliqi ◽  
Arlinda Daka

Upon entering into the biological environments, the surface of the nanoparticles is immediately coated with proteins and form the so-called a protein corona due to which a nanoparticle changes its "synthetic" identity to a new "biological" identity. Different types of nanoparticles have different protein binding profiles, which is why they have different protein corona composition and therefore it cannot be said that there is a universal protein corona. The composition and amount of protein in the corona depends on the physical and chemical characteristics of the nanoparticles, the type of biological medium and the exposure time. Protein corona increases the diameter but also changes the composition of the surface of the nanoparticles and these changes affect biodistribution, efficacy, and toxicity of the nanoparticles.


Sensors ◽  
2018 ◽  
Vol 19 (1) ◽  
pp. 113 ◽  
Author(s):  
Juan Casanova-Cháfer ◽  
Eric Navarrete ◽  
Xavier Noirfalise ◽  
Polona Umek ◽  
Carla Bittencourt ◽  
...  

The properties of multi-wall carbon nanotubes decorated with iridium oxide nanoparticles (IrOx-MWCNTs) are studied to detect harmful gases such as nitrogen dioxide and ammonia. IrOx nanoparticles were synthetized using a two-step method, based on a hydrolysis and acid condensation growth mechanism. The metal oxide nanoparticles obtained were employed for decorating the sidewalls of carbon nanotubes. Iridium-oxide nanoparticle decorated carbon nanotube material showed higher and more stable responses towards NH3 and NO2 than bare carbon nanotubes under different experimental conditions, establishing the optimal operating temperatures and estimating the limits of detection and quantification. Furthermore, the nanomaterials employed were studied using different morphological and compositional characterization techniques and a gas sensing mechanism is proposed.


2015 ◽  
Vol 119 (29) ◽  
pp. 17023-17027 ◽  
Author(s):  
Katherine E. Michaux ◽  
Alessa A. Gambardella ◽  
Leila Alibabaei ◽  
Dennis L. Ashford ◽  
Benjamin D. Sherman ◽  
...  

2018 ◽  
Vol 85 (11) ◽  
pp. 27-35 ◽  
Author(s):  
Masanori Hara ◽  
Rajashekar Badam ◽  
Guan Jhong Wang ◽  
Hsin-Hui Huang ◽  
Masamichi Yoshimura

Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 874 ◽  
Author(s):  
Juan Casanova-Cháfer ◽  
Èric Navarrete ◽  
Eduard Llobet

The properties of Iridium oxide (IrO2) decorated Multi-Wall Carbon Nanotubes (IrO2-MWCNTs) are studied for detecting nitrogen dioxide and ammonia vapors. IrO2 nanoparticles were synthetized using a hydrolysis and acid condensation growth mechanism, and subsequently employed for decorating the sidewalls of carbon nanotubes. Decorated MWCNTs films were deposited onto SiO2/Si substrates for achieving chemoresistive gas sensors. NO2 and NH3 gases were detected under different experimental conditions. Higher and more stable responses towards NH3 and NO2 were observed for iridium-oxide nanoparticle decorated MWCNT material, compared to bare MWCNT material. Raman Spectroscopy was employed to study the nanomaterials and the optimal operating temperatures were determined.


2017 ◽  
Vol 19 (24) ◽  
pp. 16151-16158 ◽  
Author(s):  
Daniel Finkelstein-Shapiro ◽  
Maxime Fournier ◽  
Dalvin D. Méndez-Hernández ◽  
Chengchen Guo ◽  
Monica Calatayud ◽  
...  

We report the first method to quantitatively understand the optical and catalytic properties of IrOx nanoparticles.


2015 ◽  
Vol 3 (26) ◽  
pp. 5166-5171 ◽  
Author(s):  
Carmen C. Mayorga-Martinez ◽  
Alejandro Chamorro-García ◽  
Lorena Serrano ◽  
Lourdes Rivas ◽  
Daniel Quesada-Gonzalez ◽  
...  

A novel impedimetric label-free genosensor for highly sensitive DNA detection using a sensing platform based on thionine and iridium oxide nanoparticles.


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