Determination of diabetic retinopathy prevalence and associated risk factors in Chinese diabetic and pre-diabetic subjects: Shanghai diabetic complications study

2012 ◽  
Vol 28 (3) ◽  
pp. 276-283 ◽  
Author(s):  
Can Pang ◽  
Lili Jia ◽  
Sunfang Jiang ◽  
Wei Liu ◽  
Xuhong Hou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Diabetic Retinopathy ◽  
Diabetic Complications ◽  
Associated Risk Factors

scholarly journals Delay in seeking medical care after the onset of symptoms in patients with sight-threatening diabetic retinopathy

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110132
Author(s):  
Yan Wei ◽  
Fenghua Mi ◽  
Yan Cui ◽  
Ying Li ◽  
Xinyi Wu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Diabetic Retinopathy ◽  
Medical Care ◽  
Diabetic Complications ◽  
Multivariate Logistic Regression Analysis ◽  
Routine Examination ◽  
Clinically Significant Macular Edema ◽  
Clinically Significant ◽  
Poor Outcomes ◽  
Associated Risk Factors

Objective To investigate the reasons for delays in seeking medical care in patients with diabetic retinopathy and associated risk factors. Methods We retrospectively reviewed data for patients with sight-threatening diabetic retinopathy (STDR) who attended a hospital in China. Various forms of STDR were identified, including severe non-proliferative DR, clinically significant macular edema and proliferative DR. Demographic, clinical and socioeconomic information was collected and the associated risk factors were evaluated. Results Of the 127 patients with STDR, 89.2% sought medical care within 1 month of developing symptoms. Those who sought treatment ≥6 months after symptoms developed had significantly lower income and less knowledge of diabetic complications than those who attended earlier. Multivariate logistic regression analysis showed that no or infrequent routine examination for diabetic complications were associated with long delays in seeking medical care (odds ratio (OR) 3.06, 95% confidence interval (CI) 1.05–9.19; and OR 2.91, 95% CI 1.04–8.40, respectively). Conclusions Most patients with STDR sought medical care within 1 month of symptoms developing, but no or infrequent routine examination for diabetic complications was associated with long delays. These results stress the importance of educational programs regarding diabetic complications to encourage timely medical care and prevent poor outcomes.

scholarly journals Prevalence and associated risk factors for diabetic retinopathy at first ophthalmological contact

2021 ◽  
Vol 12 (8) ◽  
pp. 118-124
Author(s):  
Bhavkaran Singh ◽  
Prempal Kaur ◽  
Jaspreet Singh ◽  
Parveen Grang
Keyword(s):  
Risk Factors ◽  
Diabetic Retinopathy ◽  
Observational Study ◽  
Health Concern ◽  
Accurate Estimation ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Screening Programs ◽  
Duration Of Diabetes ◽  
Associated Risk Factors

Background: Type 2 diabetes mellitus (DM) is now considered as a growing global public health concern due to cost associated with diabetic micro and macrovascular complications. Diabetic retinopathy (DR) is one of the leading causes of vision loss. Accurate estimation of prevalence of DR among diabetic patients and associated risk factors are of crucial importance to plan and execute preventive strategies in the community. Aims and Objectives: The present cross sectional hospital based observational study was undertaken to determine the prevalence of DR in diabetic patients at their first ophthalmological contact and toevaluate associated risk factors. Materials and Methods: In this cross sectional hospital based observational study, all diabetic patients visiting ophthalmology clinic for the first time after being diagnosed as diabetic were enrolled. After recording demographic data and biochemical findings, each patient was investigated for DR and correlated with associated risk factors. Results: Of 1699 patients, majority (68.9%) of them had come to ophthalmology clinic with complaint of decreased vision. Only 16.12 % (274) patients had been referred for retinal exam by treating physician. DR was prevalent in 242(16.98%) non-referred and 31(11.31%) referred patients. Mean age and mean duration of diabetes was significantly higher in non-referred patients. Vision threatening DR was also significantly higher in nonreferred patients. Prevalence of DR was significantly correlated with age at presentation, duration of diabetes, rural background, uncontrolled diabetes, systolic blood pressure and high BMI. Conclusion: Low referral by treating physician and lack of awareness among patient accounts for late presentation of diabetic patients to ophthalmologist. Beyond just developing strategies to promote screening programs for early detection and management of DR, education of the patients,comprehensive planning and coordination between ophthalmologist and physician can go a long way to decrease the economic and social burden of preventable blindness due to diabetic retinopathy.

scholarly journals Candida Isolates From Blood and Other Normally Sterile Foci From ICU Patients: Determination of Epidemiology, Antifungal Susceptibility Profile and Evaluation of Associated Risk Factors

2021 ◽  
Vol 9 ◽  
Author(s):  
Bo Wang ◽  
Xinlong He ◽  
Feng Lu ◽  
Yajuan Li ◽  
Yuerong Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Molecular Mechanisms ◽  
Antifungal Susceptibility ◽  
Resistance Mechanism ◽  
Lavage Fluid ◽  
Icu Patients ◽  
Multiple Risk Factors ◽  
Microdilution Method ◽  
Associated Risk Factors

Background: The clinical diagnosis and therapy for ICU patients with invasive candidiasis are challenged by the changes of Candida community composition and antimicrobial resistance. The epidemiology and drug sensitivity of candidiasis in ICU as well as its risk factors and drug resistance mechanism were investigated.Methods: In the present study, 115 patients in ICU were recruited from June 2019 through July 2020. Among them, 83 Candida isolates were identified with MALDI-TOF mass spectrometry. The susceptibility to antifungals was measured by microdilution method. The molecular mechanisms of azole-resistant Candida tropicalis were explored by sequencing, and their outcomes were explicitly documented.Results:Candida glabrata and C. tropicalis were the predominant non-C. albicans Candida. The specimen sources were mainly urine, bronchoalveolar lavage fluid and blood. The age, length of hospitalization, tracheotomy, diabetes and concomitant bacterial infection were the main risk factors for candidiasis. The majority of Candida species exhibited susceptibility to antifungals. However, certain C. tropicalis were frequently resistant to azoles. The polymorphism of the ERG11 in C. tropicalis was likely associated with azole resistance.Conclusion: The multiple risk factors for candidiasis in ICU patients need to be considered. Certain C. tropicalis exhibit resistance to azoles likely due to the ERG11 gene polymorphism.

Sign in / Sign up

Export Citation Format

Share Document