scholarly journals Facile preparation of tetra‐ polyethylene glycol hydrogel microspheres for drug delivery by cross‐flow membrane emulsification

2021 ◽  
Author(s):  
Jeff Henise ◽  
Brian Yao ◽  
Gary W. Ashley ◽  
Daniel V. Santi

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3067
Author(s):  
Mustafa A. Jihad ◽  
Farah T. M. Noori ◽  
Majid S. Jabir ◽  
Salim Albukhaty ◽  
Faizah A. AlMalki ◽  
...  

Flaky graphene oxide (GO) nanoparticles (NPs) were synthesized using Hummer’s method and then capped with polyethylene glycol (PEG) by an esterification reaction, then loaded with Nigella sativa (N. sativa) seed extract. Aiming to investigate their potential use as a smart drug delivery system against Staphylococcus aureus and Escherichia coli, the spectral and structural characteristics of GO-PEG NPs were comprehensively analyzed by XRD, AFM, TEM, FTIR, and UV- Vis. XRD patterns revealed that GO-PEG had different crystalline structures and defects, as well as a higher interlayer spacing. AFM results showed GONPs with the main grain size of 24.41 nm, while GONPs–PEG revealed graphene oxide aggregation with the main grain size of 287.04 nm after loading N. sativa seed extract, which was verified by TEM examination. A strong OH bond appeared in FTIR spectra. Furthermore, UV- Vis absorbance peaks at (275, 284, 324, and 327) nm seemed to be correlated with GONPs, GO–PEG, N. sativa seed extract, and GO –PEG- N. sativa extract. The drug delivery system was observed to destroy the bacteria by permeating the bacterial nucleic acid and cytoplasmic membrane, resulting in the loss of cell wall integrity, nucleic acid damage, and increased cell-wall permeability.



2021 ◽  
Vol 1 (3) ◽  
pp. 2170033
Author(s):  
Bat-hen Eylon ◽  
Alona Shagan ◽  
Ayelet Shabtay-Orbach ◽  
Adi Gross ◽  
Boaz Mizrahi




2016 ◽  
Vol 133 (36) ◽  
Author(s):  
Jiangquan Liu ◽  
Xiaoguang Ying ◽  
Hongxun Wang ◽  
Xiao Li ◽  
Weiying Zhang


2016 ◽  
Vol 18 (20) ◽  
pp. 5607-5620 ◽  
Author(s):  
Xiaoping Shen ◽  
Paula Berton ◽  
Julia L. Shamshina ◽  
Robin D. Rogers

Lignin-based hydrogels in both bulk and membrane forms for potential drug delivery, food packaging, and wound dressing applications have been designed by crosslinking ionic-liquid-isolated lignin with epoxide-terminated polyethylene glycol (ETPEG) in alkaline solution.



2013 ◽  
Vol 456 (2) ◽  
pp. 536-544 ◽  
Author(s):  
Laurent Bédouet ◽  
Florentina Pascale ◽  
Laurence Moine ◽  
Michel Wassef ◽  
Saïda H. Ghegediban ◽  
...  


2016 ◽  
Vol 4 (13) ◽  
pp. 2338-2350 ◽  
Author(s):  
Yuanyuan Guo ◽  
Boning Niu ◽  
Qingle Song ◽  
Yongdan Zhao ◽  
Yuling Bao ◽  
...  

A novel kind of copolymer, TPGS-SS-PLA, was successfully synthesized and applied in targeted drug delivery.





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