Emergency Action Plan for Flash Flood Due to Dambreak - Case study: Shahrchai Dam, Urmia (Iran)

2020 ◽  
Author(s):  
Seyed Mohammadreza Heidari ◽  
Seyed Jalal Heidari
Keyword(s):  
Flash Flood ◽  
Action Plan

Si Crans-Montana meurt. Soigner le corps malade d’une station

ARCHALP ◽  
2020 ◽  
Vol 2020 (N. 4 / 2020) ◽  
Author(s):  
Patrick Giromini
Keyword(s):  
Social Context ◽  
Alpine Meadow ◽  
Action Plan ◽  
Geographic Location ◽  
Built Heritage ◽  
Environment And Health ◽  
Health Action ◽  
The Relationship ◽  
Health Action Plan

New Alpine companies, like Crans-Montana on the Haut-Plateau, remain, more often than not, trapped in representative logic opposing the clan of modernists to that of defenders of values anchored in an ideal-typical tradition. The Haut-Plateau territory, so named due to its geographic location and topographic conformation – not for the morphology of the soil – was still a space free of any construction in the mid-nineteenth century. This vast alpine meadow was marked by a few utility buildings for sheltering cattle and hay during the intermediate seasons that precede the full summer. At the turn of the 3rd millennium, the built heritage, essentially consisting of hotel structures and holiday residences, is no longer able to welcome the new socio-economic dynamics linked to the mono-culture of skiing. This crisis calls habits, both old and new, into question, given the youth of the tourist resort. In June 2000, a Federal programme selected Crans-Montana as a case study for testing an Environment and Health Action Plan. This provided an opportunity for a group of architects to formulate an inter-municipal blueprint that activated a series of urban renewal projects. The new architectural formulae that emerge try to go beyond stylistic modernism by reinterpreting the relationship with the built environment and its social context.

scholarly journals The Biosimilar Landscape: An Overview of Regulatory Approvals by the EMA and FDA

Pharmaceutics ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 48
Author(s):  
Ioana Gherghescu ◽  
M. Begoña Delgado-Charro
Keyword(s):  
Drug Administration ◽  
Action Plan ◽  
European Medicines Agency ◽  
Patient Access ◽  
Clinical Evaluations ◽  
The Past ◽  
The Us ◽  
Improve Patient ◽  
The Eu

Biosimilar medicines expand the biotherapeutic market and improve patient access. This work looked into the landscape of the European and US biosimilar products, their regulatory authorization, market availability, and clinical evaluation undergone prior to the regulatory approval. European Medicines Agency (EMEA, currently EMA) and Food and Drug Administration (FDA) repositories were searched to identify all biosimilar medicines approved before December 2019. Adalimumab biosimilars, and particularly their clinical evaluations, were used as a case study. In the past 13 years, the EMA has received 65 marketing authorization applications for biosimilar medicines with 55 approved biosimilars available in the EU market. Since the first biosimilar approval in 2015, the FDA has granted 26 approvals for biosimilars with only 11 being currently on the US market. Five adalimumab biosimilars have been approved in the EU and commercialized as eight different medicines through duplicate marketing authorizations. Whilst three of these are FDA-approved, the first adalimumab biosimilar will not be marketed in the US until 2023 due to Humira’s exclusivity period. The EU biosimilar market has developed faster than its US counterpart, as the latter is probably challenged by a series of patents and exclusivity periods protecting the bio-originator medicines, an issue addressed by the US’s latest ‘Biosimilar Action Plan’.

scholarly journals Rainfall Threshold for Flash Flood Warning Based on Model Output of Soil Moisture: Case Study Wernersbach, Germany

Water ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1061
Author(s):  
Thanh Thi Luong ◽  
Judith Pöschmann ◽  
Rico Kronenberg ◽  
Christian Bernhofer
Keyword(s):  
Soil Moisture ◽  
Flash Flood ◽  
Rainfall Threshold ◽  
Probability Of Detection ◽  
Water Levels ◽  
Critical Success ◽  
Flood Warning ◽  
Critical Discharge ◽  
Critical Success Index

Convective rainfall can cause dangerous flash floods within less than six hours. Thus, simple approaches are required for issuing quick warnings. The flash flood guidance (FFG) approach pre-calculates rainfall levels (thresholds) potentially causing critical water levels for a specific catchment. Afterwards, only rainfall and soil moisture information are required to issue warnings. This study applied the principle of FFG to the Wernersbach Catchment (Germany) with excellent data coverage using the BROOK90 water budget model. The rainfall thresholds were determined for durations of 1 to 24 h, by running BROOK90 in “inverse” mode, identifying rainfall values for each duration that led to exceedance of critical discharge (fixed value). After calibrating the model based on its runoff, we ran it in hourly mode with four precipitation types and various levels of initial soil moisture for the period 1996–2010. The rainfall threshold curves showed a very high probability of detection (POD) of 91% for the 40 extracted flash flood events in the study period, however, the false alarm rate (FAR) of 56% and the critical success index (CSI) of 42% should be improved in further studies. The proposed adjusted FFG approach has the potential to provide reliable support in flash flood forecasting.

scholarly journals Action plan for hit identification (APHID): KAT6A as a case study

2020 ◽  
Vol 12 (5) ◽  
pp. 423-437 ◽  
Author(s):  
Xiangyan Yi ◽  
Lian Xue ◽  
Tim Thomas ◽  
Jonathan B Baell
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Action Plan ◽  
Hit Identification

Here, we describe our action plan for hit identification (APHID) that guides the process of hit triage, with elimination of less tractable hits and retention of more tractable hits. We exemplify the process with reference to our high-throughput screening (HTS) campaign against the enzyme, KAT6A, that resulted in successful identification of a tractable hit. We hope that APHID could serve as a useful, concise and digestible guide for those involved in HTS and hit triage, especially those that are relatively new to this exciting and continually evolving technology.

scholarly journals Using BAD for good: how best available data facilitated a precautionary policy change to improve protection of the prey of the tiger Panthera tigris in Malaysia

Oryx ◽  
2013 ◽  
Vol 47 (3) ◽  
pp. 420-426 ◽  
Author(s):  
Kae Kawanishi ◽  
Gopalasamy Reuben Clements ◽  
Melvin Gumal ◽  
Gareth Goldthorpe ◽  
Mohd Nawayai Yasak ◽  
...  
Keyword(s):  
Prey Species ◽  
Action Plan ◽  
Legal Protection ◽  
Camera Trapping ◽  
Panthera Tigris ◽  
Policy Changes ◽  
Illegal Hunting ◽  
Tapirus Indicus ◽  
Prey Populations

AbstractTiger Panthera tigris populations are under threat from poaching and depletion of their prey populations. The National Tiger Action Plan for Malaysia contains several actions addressing the threat of legal and illegal hunting of tiger prey species. One action in this plan required an investigation of whether urgent policy changes were needed to improve the protection of the prey of tigers, based on existing data. As the lack of reliable baseline data prevented us from determining population trends accurately, we compiled camera-trapping data from 23 studies conducted between 1997 and 2008 on four principal tiger prey species (sambar Rusa unicolor, barking deer Muntiacus muntjac, wild boar Sus scrofa and bearded pig S. barbatus) and two potential prey species (gaur Bos gaurus and Malayan tapir Tapirus indicus) and compared their distributions and relative abundances. From 10,145 wildlife photographs spanning 40,303 trap-nights, sambar, bearded pig and gaur appeared to be most threatened given their restricted distribution and low relative abundance. Among these, the gaur has full legal protection and has received more conservation attention than the other two species. Following our assessment and advocacy a 6-year moratorium on hunting both sambar and barking deer was imposed by the Malaysian government and the highest protection status possible was afforded the bearded pig. This case study illustrates how best available data (BAD), in this case from camera-trapping studies, can be harnessed to effect precautionary policy changes to curb the impacts of hunting on threatened predator and prey populations that could crash well before resources would otherwise be available for rigorous scientific assessments.

scholarly journals A Salutogenic Approach to Disaster Recovery: The Case of the Lac-Mégantic Rail Disaster

2020 ◽  
Vol 17 (5) ◽  
pp. 1463
Author(s):  
Mélissa Généreux ◽  
Mathieu Roy ◽  
Tracey O’Sullivan ◽  
Danielle Maltais
Keyword(s):  
Public Health ◽  
Health Promotion ◽  
Action Plan ◽  
Health Protection ◽  
Community Members ◽  
Community Recovery ◽  
Community Assets ◽  
Challenging Situation ◽  
Quantitative And Qualitative Methods

In July 2013, a train carrying crude oil derailed in Lac-Mégantic (Canada). This disaster provoked a major fire, 47 deaths, the destruction of 44 buildings, a massive evacuation, and an unparalleled oil spill. Since 2013, Public Health has undertaken several actions to address this challenging situation, using both quantitative and qualitative methods. Community-based surveys were conducted in Lac-Mégantic in 2014, 2015 and 2018. The first two surveys showed persistent and widespread health needs. Inspired by a salutogenic approach, Public Health has shifted its focus from health protection to health promotion. In 2016, a Day of Reflection was organized during which a map of community assets and an action plan for the community recovery were co-constructed with local stakeholders. The creation of an Outreach Team is an important outcome of this collective reflection. This team aims to enhance resilience and adaptive capacity. Several promising initiatives arose from the action plan—all of which greatly contributed to mobilize the community. Interestingly, the 2018 survey suggests that the situation is now evolving positively. This case study stresses the importance of recognizing community members as assets, rather than victims, and seeking a better balance between health protection and health promotion approaches.

scholarly journals Analysis of Catania Flash Flood Case Study by Using Combined Microwave and Infrared Technique

2014 ◽  
Vol 15 (5) ◽  
pp. 1989-1998 ◽  
Author(s):  
Francesco Di Paola ◽  
Elisabetta Ricciardelli ◽  
Domenico Cimini ◽  
Filomena Romano ◽  
Mariassunta Viggiano ◽  
...  
Keyword(s):  
Real Time ◽  
Flash Flood ◽  
Weather Prediction ◽  
Rapid Evolution ◽  
Cell Formation ◽  
Winter Season ◽  
National Research Council ◽  
Severe Weather ◽  
Synoptic Situation

Abstract In this paper, the analysis of an extreme convective event atypical for the winter season, which occurred on 21 February 2013 on the east coast of Sicily and caused a flash flood over Catania, is presented. In just 1 h, more than 50 mm of precipitation was recorded, but it was not forecast by numerical weather prediction (NWP) models and, consequently, no severe weather warnings were sent to the population. The case study proposed is first examined with respect to the synoptic situation and then analyzed by means of two algorithms based on satellite observations: the Cloud Mask Coupling of Statistical and Physical Methods (MACSP) and the Precipitation Evolving Technique (PET), developed at the National Research Council of Italy. Both of the algorithms show their ability in the near-real-time monitoring of convective cell formation and their rapid evolution. As quantitative precipitation forecasts by NWP could fail, especially for atypical convective events like in Catania, tools like MACSP and PET shall be adopted by civil protection centers to monitor the real-time evolution of deep convection events in aid to the severe weather warning service.

Remedial Action Plan Case Study

Great Lakes ◽  
2012 ◽  
pp. 268-292 ◽  
Author(s):  
John Hall ◽  
Kristin O'Connor
Keyword(s):  
Action Plan ◽  
Remedial Action ◽  
Remedial Action Plan
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