White blood cells and platelet profiles of diabetic patients at University of Gondar specialized referral hospital: A comparative cross‐sectional study

BACKGROUND: Diabetic kidney disease is a common and severe microvascular complication of diabetes mellitus (DM). There are limited data regarding alteration of urine parameters other than proteinuria among DM patients.METHODS: Institution based cross-sectional study was conducted from February to May 2017 to assess alteration of urine parameters among DM patients at the University of Gondar Hospital, Northwest Ethiopia. A Systematic random sampling technique was used to recruit adult (≥18 years) diabetic participants. Data were collected after ethical requirements had been fulfilled. The degree of association between variables was evaluated through bivariable and multivariable logistic regression models.RESULTS: The majority (69.4%) of the study participants were type 2 DM patients. The prevalence of altered urine chemical parameters was 11.3% proteinuria, 4.5% ketonuria, 13.6% hematuria, 53.8% glucosuria, 24.9% leukocyturia and 1.7% positive for nitrite. Diastolic blood pressure and poor glycemic control were significantly associated with proteinuria. Male participants were 2.4 times more likely to have leukocyturia than female participants. The prevalence of abnormally increased microscopic findings was red blood cells 3.1%, white blood cells 12.5%, epithelial cells 27.5%, yeast cells 1.7%, bacteria 17.8%, casts 3.7% and crystals 29.2%.CONCLUSIONS: The prevalence of altered urine parameters among DM patients is found to be considerable. These increased prevalences of altered urine parameters are potential indicators for diabetic kidney disease.

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Hypertension among newly diagnosed diabetic patients at Mulago National Referral Hospital in Uganda: a cross sectional study

CardioVascular Journal of Africa ◽

10.5830/cvja-2018-015 ◽

2018 ◽

Vol 29 (4) ◽

pp. 218-224 ◽

Cited By ~ 5

Author(s):

Martin Muddu ◽

Edrisa Mutebi ◽

Isaac Ssinabulya ◽

Samuel Kizito ◽

Charles Kiiza Mondo

Keyword(s):

Cross Sectional Study ◽

Referral Hospital ◽

Diabetic Patients ◽

Newly Diagnosed ◽

Sectional Study ◽

Cross Sectional ◽

Mulago National Referral Hospital ◽

National Referral Hospital

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Associations between white blood cells count and obesity in apparently healthy young adults

Nutrition & Food Science ◽

10.1108/nfs-08-2019-0270 ◽

2020 ◽

Vol 50 (6) ◽

pp. 1013-1019

Author(s):

Fatemeh Ghannadiasl

Keyword(s):

Young Adults ◽

Cardiovascular Diseases ◽

Blood Cells ◽

White Blood Cells ◽

Cross Sectional Study ◽

The Body ◽

Sectional Study ◽

Cross Sectional ◽

Content Type ◽

Apparently Healthy

Purpose The elevated white blood cells (WBCs) count has been reported to be a predictor of cardiovascular diseases, diabetes, hypertension and metabolic syndrome. This study aims to determine the associations between WBCs count and obesity in apparently healthy young adults. Design/methodology/approach In this cross-sectional study, the authors evaluated the body mass index (BMI) in 392 apparently healthy young adults of both sexes. The WBCs count was measured using standard counter techniques. The inclusion criteria were the agreement to participate in the study, between 18 and 25 years of age, lack of self-reported diseases such as cardiovascular diseases, hypertension, kidney and infectious diseases. Findings According to the BMI classification, underweight and overweight or obesity were observed in 14.58 and 11.48 per cent of young adults, respectively. The mean WBC was 6.5 ± 1.5 (×10³ cells/µL). Higher values of WBCs were found in women than in men (p = 0.02). The young adults with higher BMI had a higher WBCs count. There was a positive correlation between WBCs count and weight and BMI (r = 0.19 and r = 0.22, p < 0.001, respectively). Research limitations/implications This research was a cross-sectional study. Future studies are suggested using longitudinal studies to examine more relationships between obesity and WBCs count in apparently healthy young adults. Practical implications The results of this study provide evidence for weight management in this age group to reduce diseases associated with increased WBCs count. Originality/value The WBCs count was related to increasing levels of BMI per cent 2 C even in the normal range.

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STAT3 methylation in white blood cells as a novel sensitive biomarker for the toxic effect of low-dose benzene exposure

Toxicology Research ◽

10.1039/c5tx00445d ◽

2016 ◽

Vol 5 (3) ◽

pp. 800-807 ◽

Cited By ~ 3

Author(s):

Di Liu ◽

Yujiao Chen ◽

Pengling Sun ◽

Wenlin Bai ◽

Ai Gao

Keyword(s):

Dna Methylation ◽

Toxic Effect ◽

Health Effects ◽

Blood Cells ◽

Low Dose ◽

White Blood Cells ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Benzene Exposure

A cross-sectional study was conducted in a sample of 571 workers to explore the toxic effect and early sensitive biomarker of the health effects of low-dose benzene exposure (LDBE), as well as the correlation between DNA methylation and the toxic effect of LDBE.

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