Low-dose (2 μg) hepatitis B vaccination in medical students: Comparable immunogenicity for intramuscular and intradermal routes

AbstractIntroductionMedical students are mainly exposed to needle stick and sharp object injuries in the course of their clinical activities during studying. They are at high risk due to their undeveloped skills, restricted clinical experience, lack of knowledge and risk perception. The objectives of this study were to determine the prevalence of needle stick injuries of the fourth and final year medical students, and to estimate their knowledge about blood-borne pathogens disease transmission and standard precautions.MethodsThis cross-sectional study was conducted at the Faculty of Medicine, in February 2014. The students were invited to self-administer a questionnaire of 26 closed questions prepared for this study.ResultsThe questionnaire was filled in and returned by 637 students. The prevalence of needle sticks and sharp object injuries was 29.5%. Needle stick injuries were the most common type of accidents, more frequent among the fourth compared to the sixth year students (p=0.002). The majority of accidents occurred in patient rooms (53%) and the emergency department (15%). 54% of participants reported an accident to the responsible person. Students without accidents had a significantly better perception of risk (3.79 vs. 3.35; p<0.05). Out of the total participating students, only 16.6% (106/637) received all three doses of Hepatitis B vaccination, while 16.2% were partially vaccinated.ConclusionsThere is a need for additional theoretical and practical education of our students on blood exposure via accidents, raising the awareness of the necessity of hepatitis B vaccination, and introducing the unique/comprehensive procedure for accident reporting for students and healthcare workers in the entire country.

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Hepatitis B Awareness Among Medical Students And Their Vaccination Status In A Medical College In Western UP.

10.36106/ijsr/0601604 ◽

2019 ◽

pp. 57-59

Author(s):

Rajni Dawar ◽

Tabassum Yasmin ◽

Ajay Kumar Jha

Keyword(s):

Medical Students ◽

High Risk ◽

Data Collection ◽

Hepatitis B ◽

Health Care Professionals ◽

Hepatitis B Surface Antigen ◽

Vaccination Status ◽

Hepatitis B Vaccination ◽

Universal Precautions ◽

Medical College

Background: India is in the intermediate hepatitis B virus endemicity zone with hepatitis B surface antigen prevalence among the general population ranging from 2% to 8%.Health care professionals are at a high risk of getting .Hep B infection which can be prevented by strategies like vaccination, increasing awareness and following universal precautions. The present study was conducted on medical students (3rd Semester) to evaluate their knowledge regarding HBV and to know their vaccination status. Also along with data collection, students were educated about hepatitis B vaccine and about universal precautions before they start with their clinical postings. Methods: Cross sectional study was carried out on 3rd semester MBBS students (batch 2012-2013). All the students present on the day of data collection were included in the study and interviewed using pretested questionnaire. Data was analyzed using percentages. Results: Most of the students had good knowledge about disease and modes of transmission & prevention. Surprisingly only 56.6 percent were aware of high risk of transmission to health professional and doctors. Main source of information was media (85.4percent).Nearly 82% of the students were immunized and main reason among those unimmunized was unawareness about vaccine availability. Conclusions: It is recommended that Hepatitis B vaccination should be made available for all unimmunized students who enter medical profession. The orientation and sensitization programm should be held to create awareness regarding HBV infection preferably at the time of admission into medical college ,else no later than start of their clinical posting.

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A STUDY TO ASSESS THE SEROPREVALENCE OF HEPATITIS B AND ANTI HBS ANTIBODY LEVELS AMONGST HEALTH CARE WORKERS AND MEDICAL STUDENTS.

10.36106/ijsr/8002609 ◽

2021 ◽

pp. 84-85

Author(s):

Aditya Rana ◽

Anuradha Sood

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Healthcare Workers ◽

Base Material ◽

Hepatitis B Vaccination ◽

Continuous Exposure ◽

Cross Sectional ◽

Antibody Titres ◽

Antibody Titers ◽

Antibody Levels

Background: Hepatitis B(HBV) is a blood borne virus and it is one of the most important occupational hazards among healthcare workers (HCWs) & Medical students. This study aimed to measure the anti-HBs titres and to assess the seroprevalence of Hepatitis B in HCW and medical students. It was a prospective,descriptive and cross sectional hospital base Material and method: d study. Medical students and healthcare workers who had received all three doses of hepatitis B vaccination were included in the study. A total of 200 subjects , aged between 18 and Result: 62 years were taken. 182 were vaccinated and 18 were unvaccinated. 85 were males and 115 females. Seroprevalence of Hepatitis B was nil. Antibody titres were >100mIU/ml in 51.6% , 10-100mIU/ml in 16.4% & <10 mIU/ml in 31.8% respectively.Negative correlation of decreasing antibiotic titer and age was seen. HCW and medical students are at hi Conclusion: gher risk due to their continuous exposure to blood products. Vaccination should be compulsory to the HCW and medical workers in the institution as Hepatitis B is a preventable disease. Monitoring of antibody titers should be done from time to time to see waning off antibody titers after vaccination

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Hepatitis B Vaccination in Hospital Personnel and Medical Students

Journal of Clinical Gastroenterology ◽

10.1097/00004836-199906000-00007 ◽

1999 ◽

Vol 28 (4) ◽

pp. 317-322 ◽

Cited By ~ 9

Author(s):

Rui T. Marinho ◽

Miguel C. Moura ◽

Marília Pedro ◽

Fernando J. Ramalho ◽

José F. Velosa

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Hepatitis B Vaccination ◽

Hospital Personnel

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Low Dose Intradermal Versus High Dose Intramuscular Hepatitis B Vaccination in Patients on Chronic Hemodialysis

ASAIO Journal ◽

10.1097/01.mat.0000161935.66158.97 ◽

2005 ◽

Vol 51 (3) ◽

pp. 242-245 ◽

Cited By ~ 18

Author(s):

Jamshid Roozbeh ◽

Maryam Moini ◽

Kamran Bagheri Lankarani ◽

Mohamad Medhi Sagheb ◽

Sedigheh Shahpoori ◽

...

Keyword(s):

Hepatitis B ◽

Low Dose ◽

Chronic Hemodialysis ◽

Hepatitis B Vaccination ◽

High Dose

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Hepatitis B vaccination programmes for medical students and other health care workers are needed

Inpharma Weekly ◽

10.2165/00128413-199007540-00008 ◽

1990 ◽

Vol &NA; (754) ◽

pp. 4

Author(s):

&NA;

Keyword(s):

Health Care ◽

Medical Students ◽

Hepatitis B ◽

Health Care Workers ◽

Hepatitis B Vaccination ◽

Care Workers

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Efficacy of hepatitis B vaccination: knowledge among clinical medical students.

BMJ ◽

10.1136/bmj.307.6899.301 ◽

1993 ◽

Vol 307 (6899) ◽

pp. 301-301 ◽

Cited By ~ 9

Author(s):

B C Oates ◽

A J Sidebottom ◽

S R Maxwell

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Hepatitis B Vaccination ◽

Vaccination Knowledge

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Hepatitis B vaccination status and knowledge, attitude, and practice regarding Hepatitis B among preclinical medical students of a medical college in Nepal

PLoS ONE ◽

10.1371/journal.pone.0242658 ◽

2020 ◽

Vol 15 (11) ◽

pp. e0242658

Author(s):

Dhan Bahadur Shrestha ◽

Manita Khadka ◽

Manoj Khadka ◽

Prarthana Subedi ◽

Subashchandra Pokharel ◽

...

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Vaccination Status ◽

Hepatitis B Vaccination ◽

Vaccination Programs ◽

Medical College ◽

Attitude And Practice ◽

Preclinical Medical Students ◽

Study Participants ◽

Knowledge Attitude And Practice

Background Hepatitis B imposes a major public health problem with an increased risk of occupational exposure among unvaccinated health care workers. This study was conducted to determine the Hepatitis B vaccination status, along with the knowledge, attitude, and practice regarding Hepatitis B, among preclinical medical students of a medical college in Nepal. Materials and methods This descriptive study was conducted among preclinical students of a medical college in Kathmandu, Nepal from 6th July to 14th July 2020. The whole sampling technique was used. Data were collected using a pretested, self-administered questionnaire which was emailed to individuals and analyzed with the statistical package for social sciences version-22. Results A total of 181 students participated in the study out of 198, giving a response rate of 91.4%. Among the study participants, only 67 (37%) were fully vaccinated against Hepatitis B while 71 (39.2%) were never vaccinated. For the majority (74.6%) of the non-vaccinated participants, the main reason for not getting vaccination was a lack of vaccination programs. Half the study participants (n = 92, 50.8%) had good knowledge, attitude and practice regarding hepatitis B. The median knowledge, attitude and practice scores towards Hepatitis B were 61.00 (57.00–66.00), 20(18.00–21.00) and 21(19.00–23.00) respectively. Conclusions The majority of preclinical medical students were not fully vaccinated against Hepatitis B and only half of them had acceptable knowledge, attitude and practice towards Hepatitis B, which makes them vulnerable to the infection. This might represent the situation of not only Nepal, but also all South Asian countries, and creates concern about whether students take the vaccination programs seriously. Since unavailability of vaccination program is the main cause of non-vaccination, we strongly recommend the provision of the Hepatitis B vaccination program to the preclinical medical students.

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