Bovicin HC5 and nisin reduce cell viability and the thermal resistance of Alicyclobacillus acidoterrestris endospores in fruit juices

2022 ◽  
Author(s):  
Aryádina Mara Ribeiro ◽  
Aline Dias Paiva ◽  
Alexandra Manoela Oliveira Cruz ◽  
Maria Cristina Dantas Vanetti ◽  
Sukarno Olavo Ferreira ◽  
...  
Keyword(s):  
Thermal Resistance ◽  
Cell Viability ◽  
Fruit Juices ◽  
Alicyclobacillus Acidoterrestris ◽  
Bovicin Hc5 ◽  
Reduce Cell Viability

scholarly journals Bovicin HC5 reduces thermal resistance of Alicyclobacillus acidoterrestris in acidic mango pulp

2008 ◽  
Vol 104 (6) ◽  
pp. 1685-1691 ◽  
Author(s):  
A.A.T. de Carvalho ◽  
M.C.D. Vanetti ◽  
H.C. Mantovani
Keyword(s):  
Thermal Resistance ◽  
Alicyclobacillus Acidoterrestris ◽  
Bovicin Hc5 ◽  
Mango Pulp

scholarly journals Synthesis and Cytotoxic Activity of Chiral Sulfonamides Based on the 2-Azabicycloalkane Skeleton

Molecules ◽  
2020 ◽  
Vol 25 (10) ◽  
pp. 2355 ◽  
Author(s):  
Mahzeiar Samadaei ◽  
Matthias Pinter ◽  
Daniel Senfter ◽  
Sibylle Madlener ◽  
Nataliya Rohr-Udilova ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Viability ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Diels Alder ◽  
Human Hepatocellular Carcinoma ◽  
Sulfonyl Chlorides ◽  
Reduce Cell Viability

A series of chiral sulfonamides containing the 2-azabicycloalkane scaffold were prepared from aza-Diels–Alder cycloadducts through their conversion to amines based on 2-azanorbornane or the bridged azepane skeleton, followed by the reaction with sulfonyl chlorides. The cytotoxic activity of the obtained bicyclic derivatives was evaluated using human hepatocellular carcinoma (HCC), medulloblastoma (MB), and glioblastoma (GBM) cell lines. Chosen compounds were shown to notably reduce cell viability as compared to nonmalignant cells.

scholarly journals Comparison on the Cancer Specific Cytotoxicity of Three Gingers (Zingiber officinale Rosc) Leaves Varieties from Indonesia

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Susanti S. ◽  
Kumoro C. A. ◽  
Santoso I. S. ◽  
Murwanti R. ◽  
Suzery M. ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cancer Cell ◽  
Detrimental Effect ◽  
Zingiber Officinale ◽  
Assay Method ◽  
Human Breast ◽  
Normal Cells ◽  
Specific Cytotoxicity ◽  
Reduce Cell Viability ◽  
Mcf 7

This study was performed to get more insight the cancer specific cytotoxicity of ginger leaf (GL). Three GL varieties (Gajah, Emprit, and Red) were extracted and fractionated. Each etyl acetate fraction in concentration of 200 µg/ml was tested about specific cytotoxicity toward cancer dan normal cells. Cancer cell lines used in this study were human colorectal (HCT116) and human breast (MCF-7 and T47D) cancer while normal cell line was human fibroblast (KMST-6). Based MTS assay method, the results showed Gajah and Emprit GL more significantly reduce cell viability of HCT116 and T47D than Red GL although there was no difference on the efficacy of both varieties. All varieties of GL also significantly reduce cell viability of MCF-7 compare to PBS control. However, there were not significant differences between those GL varieties on their effectiveness against MCF-7. In contrast, there were no effects on the KMST-6 due to all GL varieties treatment compare with PBS control. All data suggested that GL treatment only inhibited in the cancer cells without detrimental effect in the normal cells. Effectiveness of GL against cancer cell varies depend on the varieties. Gajah and Emprit GL are better varieties possess the cancer specific cytotoxicity that merits to be developed as promising chemo preventive agent in the future.

scholarly journals Differential responses of pancreatic β-cells to ROS and RNS

2013 ◽  
Vol 304 (6) ◽  
pp. E614-E622 ◽  
Author(s):  
Gordon P. Meares ◽  
Dominique Fontanilla ◽  
Katarzyna A. Broniowska ◽  
Teresa Andreone ◽  
Jack R. Lancaster ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Dna Damage ◽  
Cell Death ◽  
Cell Viability ◽  
Cell Fate ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Unfolded Protein ◽  
Heat Shock Responses ◽  
Reduce Cell Viability

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) direct the activation of distinct signaling pathways that determine cell fate. In this study, the pathways activated and the mechanisms by which ROS and RNS control the viability of pancreatic β-cells were examined. Although both nitric oxide and hydrogen peroxide (H2O2) induce DNA damage, reduce cell viability, and activate AMPK, the mechanisms of AMPK activation and cell death induction differ between each reactive species. Nitric oxide activates the unfolded protein and heat shock responses and MAPK kinase signaling, whereas H2O2 stimulates p53 stabilization and poly(ADP-ribose) polymerase (PARP) activation but fails to induce the unfolded protein or heat shock responses or MAPK activation. The control of cell fate decisions is selective for the form of stress. H2O2-mediated reduction in β-cell viability is controlled by PARP, whereas cell death in response to nitric oxide is PARP independent but associated with the nuclear localization of GAPDH. These findings show that both ROS and RNS activate AMPK, induce DNA damage, and reduce cell viability; however, the pathways controlling the responses of β-cells are selective for the type of reactive species.

scholarly journals P54 * THE USE OF FOLATE TO REDUCE CELL VIABILITY IN GLIOMA CELLS

2014 ◽  
Vol 16 (suppl 6) ◽  
pp. vi9-vi9
Author(s):  
M. Rudd ◽  
R. Lea ◽  
W. Goodwin
Keyword(s):  
Cell Viability ◽  
Glioma Cells ◽  
Reduce Cell Viability

scholarly journals Polyphenols of selected peach and plum genotypes reduce cell viability and inhibit proliferation of breast cancer cells while not affecting normal cells

2014 ◽  
Vol 164 ◽  
pp. 363-370 ◽  
Author(s):  
Marcia Vizzotto ◽  
Weston Porter ◽  
David Byrne ◽  
Luis Cisneros-Zevallos
Keyword(s):  
Breast Cancer ◽  
Cell Viability ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Normal Cells ◽  
Reduce Cell Viability

scholarly journals Alicyclobacillus acidoterrestris in pasteurized exotic Brazilian fruit juices: Isolation, genotypic characterization and heat resistance

2010 ◽  
Vol 27 (8) ◽  
pp. 1016-1022 ◽  
Author(s):  
I.C. McKnight ◽  
M.N.U. Eiroa ◽  
A.S. Sant’Ana ◽  
P.R. Massaguer
Keyword(s):  
Heat Resistance ◽  
Fruit Juices ◽  
Alicyclobacillus Acidoterrestris ◽  
Genotypic Characterization
Sign in / Sign up

Export Citation Format

Share Document